A5048764693- Schizophrenia research and treatment
- Mental Health and Psychiatry
- Mental Health Research Topics
- Psychosomatic Disorders and Their Treatments
- Psychology of Moral and Emotional Judgment
- Misinformation and Its Impacts
- Tryptophan and brain disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Vaccine Coverage and Hesitancy
- Health Systems, Economic Evaluations, Quality of Life
- Digital Mental Health Interventions
- Stress Responses and Cortisol
- Child and Adolescent Psychosocial and Emotional Development
- Decision-Making and Behavioral Economics
- Personality Disorders and Psychopathology
- Functional Brain Connectivity Studies
- Autism Spectrum Disorder Research
- Mobile Health and mHealth Applications
- Psychotherapy Techniques and Applications
- Eating Disorders and Behaviors
- Clinical Reasoning and Diagnostic Skills
- Deception detection and forensic psychology
- Perfectionism, Procrastination, Anxiety Studies
- Mental Health Treatment and Access
- Menopause: Health Impacts and Treatments
Flinders University
2016-2025
Adelaide Institute for Sleep Health
2022-2025
ARC Centre of Excellence in Cognition and its Disorders
2016-2020
Macquarie University
2016-2020
The University of Adelaide
2012-2020
Abstract The kynurenine pathway (KP) of tryptophan (TRP) catabolism links immune system activation with neurotransmitter signaling. KP metabolite kynurenic acid (KYNA) is increased in the brains people schizophrenia. We tested extent to which: (1) brain enzyme mRNAs, (2) metabolites, and (3) plasma metabolites differed on basis elevated cytokines schizophrenia vs. control groups which were associated cognition volume patients displaying peripheral cytokines. mRNAs assayed two independent...
There is increasing clinical and molecular evidence for the role of hormones specifically estrogen its receptor in schizophrenia. A selective modulator, raloxifene, stimulates estrogen-like activity brain can improve cognition older adults. The present study tested extent to which adjunctive raloxifene treatment improved reduced symptoms young middle-age men women with Ninety-eight patients a diagnosis schizophrenia or schizoaffective disorder were recruited into dual-site, thirteen-week,...
Cognitively distinct subgroups of schizophrenia have been defined based on premorbid and current IQ, but little is known about the neuroanatomical differences among these cognitive subgroups.To confirm previous findings related to IQ-based patients with in an independent sample extend those determine extent which brain volumetric correspond subgroups.A total 183 participants were assessed at outpatient settings Neuroscience Research Australia Lyell McEwin Hospital from September 22, 2009,...
There is increasing evidence for the role of inflammation in schizophrenia, yet stability increased peripheral acute psychosis and degree to which relates cortical thickness, a measure neuropathology, are unknown. In independent samples, we assessed marker C-reactive protein (CRP) determine extent which: 1) CRP was elevated stable across admissions psychosis, 2) cognition, daily function symptom severity characteristic chronically ill patients with schizophrenia displaying CRP, 3) levels...
Objective: Previous research has consistently shown that individuals with delusions typically exhibit a jumping to conclusions (JTC) bias when administered the probabilistic reasoning ‘beads task’ (i.e. decisions made limited evidence or ‘premature decisions’ and over-adjusted in light of disconfirming ‘over-adjustment’). More recent work, however, also suggests these effects may be influenced by miscomprehension task. The current paper is an investigation into contributing on JTC bias....
It has been previously demonstrated that a cognitive bias against disconfirmatory evidence (BADE) is associated with delusions. However, small samples of delusional patients, reliance on difference scores and choice comparison groups may have hampered the reliability these results. In present study we aimed to improve this methodology recent version BADE task, compare larger schizophrenia patients with/without delusions obsessive-compulsive disorder (OCD) population persistent possibly...
Metacognitive training is an eight-module, group-based treatment programme for people with schizophrenia that targets the cognitive biases (i.e. problematic thinking styles) thought to contribute genesis and maintenance of delusions. The present article investigation into efficacy a shorter, more targeted, single-module metacognitive programme, administered individually, which focuses specifically on improving are be driven by 'hypersalience evidence-hypothesis matches' mechanism (e.g....
Hypersalience of evidence-hypothesis matches has recently been proposed as the cognitive mechanism responsible for biases, which, in turn, may contribute to formation and maintenance delusions. However, supporting evidence this construct is still required. Using two tasks designed elicit three core facets confirmation bias (i.e., biased search confirming evidence; interpretation recall evidence), article investigated possibility that individuals with delusions those identified delusion-prone...
Abstract Although many psychological and sociological factors have been implicated in the development of conspiracy theory (CT) beliefs, analytical thinking has considered a key protective factor. However, it is not clear if engaging systematic or rigorous information searching always protective, particularly this involves confirmation bias lack scientific reasoning. For example, higher scores on autistic traits, which are commonly associated with tendency to engage searching, found be...
There is widespread agreement that delusions in clinical populations and delusion-like beliefs the general population are, part, caused by cognitive biases. Much of evidence comes from two influential tasks: Beads Task Bias Against Disconfirmatory Evidence Task. However, research using these tasks has been hampered conceptual empirical inconsistencies. In an online study, we examined relationships between biases associated with tasks. Our study had four key strengths: A new animated designed...
Jumping to conclusions (JTC) distinguishes patients with schizophrenia from both healthy and psychiatric controls. JTC is typically assessed using the beads task, which, however, faces a number of limitations as its interpretability reliability. The present study set out validate new paradigm assess JTC: box task. We adopted psychometric psychosis proneness approach divided large population sample into participants who scored high versus low on scale tapping psychosis-like experiences....
Conspiracy theory (CT) beliefs are thought to be related a number of individual differences that make certain individuals more prone this style reasoning. In study, we investigate (a) the relationship between CT and standardized measure judgment (the Bias Against Disconfirmatory Evidence task or BADE) (b) extent which BADE scores specific measures psychopathology, including schizotypy delusion-proneness, as measured by Peters et al.’s Delusions Inventory. The is an evidence integration bias...
This study investigates the feasibility and preliminary evidence for efficacy of a single-session online metacognitive training (MCT-ED) among population considered to be at-risk developing an eating disorder. A total N = 95 participants with high weight concerns were randomised MCT-ED condition (n 43) or waitlist control 52). Participants completed measures body image flexibility, perfectionism, shape mood at baseline, post-treatment (one-week post-baseline), 3-months post-treatment. The...
People are exposed to misinformation about dieting practices every day on social media which can influence their health and wellbeing. While research has largely focused general vulnerabilities strategies counteract its spread, limited work examined how specific harmful content, such as dietary misinformation, influences vulnerable groups, particularly those at risk of eating disorders (EDs). This study investigated whether individuals an ED were more likely endorse Dietary Misinformation....