A5056225134- Ear Surgery and Otitis Media
- Head and Neck Surgical Oncology
- Head and Neck Cancer Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Tumors and Oncological Cases
- Hearing Loss and Rehabilitation
- Tracheal and airway disorders
- Vestibular and auditory disorders
- Ear and Head Tumors
- Prostate Cancer Diagnosis and Treatment
- Oral health in cancer treatment
- Cancer Immunotherapy and Biomarkers
- Oral and Maxillofacial Pathology
- Advanced MRI Techniques and Applications
- Sinusitis and nasal conditions
- Pituitary Gland Disorders and Treatments
- Synthesis of Organic Compounds
- Traumatic Brain Injury Research
- Advanced Radiotherapy Techniques
- Nasal Surgery and Airway Studies
- Virology and Viral Diseases
- Facial Nerve Paralysis Treatment and Research
- Adrenal Hormones and Disorders
- Chemokine receptors and signaling
- MRI in cancer diagnosis
Michigan Ear Institute
2022-2023
Baylor College of Medicine
2017-2021
The University of Texas MD Anderson Cancer Center
2009-2020
Audie L. Murphy Memorial VA Hospital
2014
The University of Texas Health Science Center at San Antonio
2014
Abstract Background Recurrent immunotherapy‐induced audiovestibular toxicity despite cessation of therapy has not been reported. Methods We report the first case recurrent following immune‐checkpoint inhibitor (ICI) therapy. The patient was seen with sudden bilateral hearing loss and disequilibrium. After ruling out other etiologies, he diagnosed neurological immune‐related adverse events (irAEs). He received systemic steroids, significant balance recovery. Over 4 months, experienced two...
Background Intranasal injection of epinephrine and placement topical pledgets are methods to improve visualization during endoscopic sinonasal surgery. Studies comparing the hemodynamic effects these vasoconstrictors using intraoperative arterial line monitoring lacking. Methods Twenty‐eight patients undergoing skull‐base surgery were enrolled in a prospective, randomized study. Patients have either 2 mL 1:100,000 or 1:200,000 injected intranasally. Hemodynamic parameters, including pulse,...
Ototoxicity is an important side effect of cisplatin. Recent animal and in vitro studies suggest metformin may protect hearing, though human are lacking. We report the first retrospective clinical study exploring effects on cisplatin-induced ototoxicity.
Abstract Objective This project compares the degree of tracheal collapse determined by rigid and flexible bronchoscopy in paediatric patients with tracheomalacia. Methods A total nine tracheomalacia underwent both video bronchoscopy. All were breathing spontaneously. Cross-sectional images airway processed using ImageJ program analysed via colour histogram mode technique order to delineate luminal area. Paired t -tests (conducted Stata software version 13.0) quantified differences between...
Objectives The aim of the study is to evaluate effect preoperative vascular embolization (PVE) on juvenile nasopharyngeal angiofibroma (JNA) surgical outcomes using a national pediatric hospitalization database. Methods health care cost and utilization project Kids' Inpatient Database was queried for all cases operative management JNA between years 1997 2016. Cases were stratified based whether patient received PVE. A multiple linear regression used predict PVE hospital length stay (LOS)...
Objective: To report trends in Juvenile Nasopharyngeal Angiofibroma (JNA) hospitalizations and identify key factors affecting treatment outcomes cost of care JNA patients. Methods: The Healthcare Cost Utilization Project (HCUP) Kids’ Inpatient Database was queried for all cases between the years 1997 2016. Key extracted were patient demographics, geographic region, hospital size, teaching status, elective admissions, number diagnoses procedures performed during hospitalization. These...
Objective: To investigate the evolving prevalence of otosclerosis in a large urban population. Methods: A retrospective review patients large, urban, public health system was conducted from January 2010 to August 2019 identify subjects with otosclerosis. Diagnostic testing included audiometry and computed tomography scans. Sex, age at diagnosis, treatment received, race, ethnicity, country birth were analyzed for each subject compared all eligible reference Results: total 134 population...
Objective Approximately 50 million US adults experience chronic tinnitus, yet search behaviors and topics of concern to these patients have not been investigated on a national level. Study Design Observational Setting Online database tertiary otology clinic Patients Nationwide institutional samples Interventions None Main Outcome Measure A engine optimization tool was utilized extract metadata “People Also Ask” (PAA) questions pertaining tinnitus. Website quality assessed using JAMA...
Objective Evaluate the safety and efficacy of exoscope-assisted stapedotomy. Study Design Retrospective chart review. Setting Tertiary care neurotology clinic. Patients Adult patients with otosclerosis undergoing Intervention(s) Primary Main Outcome Measure(s) Evaluation audiologic outcomes, including pure-tone average, bone-conduction thresholds, word recognition score, air-bone gap. Complications, need for scutum removal, length surgery were also evaluated. Results A total 47 identified,...
Objective: Temporal bone osteoradionecrosis (TBORN) is a rare, chronic complication of head and neck radiation. Initial treatment consists conservative management, with surgical resection necrotic indicated for cases severe, symptomatic, or progressive disease. Pentoxifylline-tocopherol (PENTO) has demonstrated usefulness other subsites. Herein, we report five TBORN utilizing this protocol. Study Design: Retrospective case series. Setting: Tertiary referral center. Patients: This series...
Objectives/Hypothesis To report the largest single‐institution review of temporal bone osteoradionecrosis (TBORN), and characterize disease's natural history, prognostic factors, management, outcomes. Study Design Retrospective chart review. Methods was conducted to identify patients with TBORN. Pertinent data were extracted. Descriptive statistics used summarize patient, tumor, treatment characteristics. Multivariable analyses explore associations between these characteristics time TBORN...
Objective To report on the novel use of simultaneous cochlear implantation (CI) during salvage translabyrinthine resection vestibular schwannoma (VS) after failed stereotactic radiosurgery (SRS). Patient A 52-year-old woman presented with a medium-sized right VS. She experienced continued tumor growth despite previous SRS, resulting in medial extension beyond internal auditory canal into cerebellopontine angle. Associated symptoms included asymmetrical moderate to severe sensorineural...
Abstract Objective To investigate the effect of body mass index on hearing outcomes, operative time and complication rates following stapes surgery. Method This is a five-year retrospective review 402 charts from single tertiary otology referral centre 2015 to 2020. Results When patient's shoulder was adjacent surgeon's dominant hand, average 40 minutes increased 70 because significant positive association between higher longer times (normal group (<25 kg/m 2 ) r = 0.273, p 0.032;...
Objectives: The aim is to evaluate the effect of preoperative vascular embolization (PVE) on juvenile nasopharyngeal angiofibroma (JNA) surgical outcomes using a national pediatric hospitalization database.
Abstract Background To evaluate the utilization of image guidance technology for pediatric transsphenoidal pituitary resection (TSPR) and analyze complication rates, length stay (LOS), total cost such surgeries as function time guidance. Methods The Healthcare Cost Utilization Project Kids' Inpatient Database (KID) was queried all cases TSPR between 1997 2016. Factors extracted included patient demographics, use guidance, LOS, cost, complications, including panhypopituitarism, diabetes...