A5014216264- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Orthopedic Infections and Treatments
- Gout, Hyperuricemia, Uric Acid
- Meta-analysis and systematic reviews
- Osteoarthritis Treatment and Mechanisms
- Musculoskeletal pain and rehabilitation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Musculoskeletal synovial abnormalities and treatments
- Systemic Sclerosis and Related Diseases
- Bone and Joint Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Dupuytren's Contracture and Treatments
- Peripheral Neuropathies and Disorders
- French Urban and Social Studies
- Lipoproteins and Cardiovascular Health
- Hepatitis C virus research
- Infectious Diseases and Tuberculosis
- Pain Mechanisms and Treatments
- Chronic Lymphocytic Leukemia Research
- Bacterial Identification and Susceptibility Testing
- Delphi Technique in Research
- Psoriasis: Treatment and Pathogenesis
Centre Hospitalier Universitaire de Clermont-Ferrand
2016-2025
Université Clermont Auvergne
2011-2025
Inserm
2009-2025
Center for Rheumatology
2013-2023
Société Française de Rhumatologie
2017-2022
Université de Montpellier
2015-2021
Université de Lille
2021
Hôpital Beaujon
2021
Hôpital Européen Georges-Pompidou
2021
Centre Hospitalier Gabriel-Martin
2020-2021
As of 2005, the International Committee Medical Journal Editors required investigators to register their trials prior participant enrollment as a precondition for publishing trial's findings in member journals.To assess proportion registered with results recently published journals high impact factors; compare primary outcomes specified trial registries those reported articles; and determine whether outcome reporting bias favored significant outcomes.MEDLINE via PubMed was searched reports...
Abstract Background Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by increased mortality associated with cardiometabolic disorders including dyslipidaemia, insulin resistance, and cachectic obesity. Tumour necrosis factor inhibitors interleukin 6 receptor blocker licensed for the treatment of RA decrease inflammation could thus improve cardiovascular risk, but their effects on body composition metabolic profile need to be clarified. We investigated tocilizumab...
The SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis) is a rare disease and only few series have been published about it. We describe the experience of rheumatology department with focus on therapeutic aspects.All cases fulfilling Benhamou criteria seen between 1992 2013 in our unit were retrospectively included.Forty-one patients (11 men 30 women) included. average age was 45 years (20-80 yrs) at time diagnosis. Nineteen had palmoplantar 3 psoriasis vulgaris, severe 15 no...
Increased incidence of cardiovascular disease (CVD) has been observed in AS. The reasons this increase are not fully understood (greater prevalence traditional risks, consequences treatment (NSAID) or biological inflammation). objectives study to assess intima-media thickness (IMT) and arterial stiffness (i.e augmentation index AIx), markers sub-clinical atherosclerosis AS patients examine the effects TNF-alpha inhibitors on active patients.Sixty were enrolled with 60 healthy controls. Their...
BACKGROUND AND AIMS: Transient lower oesophageal sphincter relaxations (TLOSRs) has been found to be the main mechanism of gastro-oesophageal reflux. In dogs, cholecystokinin (CCK) is involved in their occurrence. The aim was evaluate role endogenous and exogenous CCK occurrence TLOSRs induced by gastric distension at constant pressure humans. METHODS: Ten healthy volunteers were studied. Lower monitored with a sleeve device performed via an intragastric bag barostat. During distensions,...
Evidence in the medical literature suggests that trial registration may not be preventing selective reporting of results. We wondered about place such information peer-review process.We asked 1,503 corresponding authors clinical trials and 1,733 reviewers to complete an online survey soliciting their views on use registry during process.1,136 (n = 713) 423) responded (37.5%); 676 (59.5%) had reviewed article a past 2 years. Among these, 232 (34.3%) examined registered registry. If one or...
Objective. The increased cardiovascular risk associated with AS is attributable to multiple factors: disease activity, systemic inflammation, traditional factors and NSAIDs. This study aimed investigate the effects of 24 52 weeks TNF-α inhibitor treatment on arterial stiffness factors.