A5004239999- Melanoma and MAPK Pathways
- Magnolia and Illicium research
- Cell Image Analysis Techniques
- Cancer Genomics and Diagnostics
- melanin and skin pigmentation
- CRISPR and Genetic Engineering
- Immunotherapy and Immune Responses
- Cancer Cells and Metastasis
- Epigenetics and DNA Methylation
- Cancer Immunotherapy and Biomarkers
- 3D Printing in Biomedical Research
- Cell Adhesion Molecules Research
- Cutaneous Melanoma Detection and Management
- Inflammasome and immune disorders
- Computational Drug Discovery Methods
- Autophagy in Disease and Therapy
- Menopause: Health Impacts and Treatments
- Amino Acid Enzymes and Metabolism
- Protein Degradation and Inhibitors
- Biomarkers in Disease Mechanisms
- Piperaceae Chemical and Biological Studies
- Neonatal Health and Biochemistry
- Diabetes and associated disorders
- Cancer Risks and Factors
- Emergency and Acute Care Studies
Dana-Farber Brigham Cancer Center
2022-2024
Dana-Farber Cancer Institute
2022-2024
Brigham and Women's Hospital
2022-2024
Harvard University
2022-2024
Shaheed Suhrawardy Medical College
2022-2024
Ibrahim Cardiac Hospital & Research Institute
2022
The University of Sydney
2021
Royal Prince Alfred Hospital
2021
Melanoma Institute Australia
2021
Centenary Institute
2021
Nutritional anemia is one of India's major public health problems. The prevalence ranges from 33% to 89% among pregnant women and more than 60% adolescent girls. Under the prevention control program Government India, iron folic acid tablets are distributed women, but no such exists for girls.To assess status girls 16 districts 11 states India.A two-stage random sampling method was used select 30 clusters on basis probability proportional size. Anemia diagnosed by estimating hemoglobin...
The emergence of new pathogenic bacteria resistant to most, if not all, currently existing antimicrobial agents has become a serious problem in modern medicine, particularly because the affiliated increase immunosuppressed inhabitants worldwide.The recent surfacing E. coli O157:H7 as foremost food pathogen is lively reminder its dynamic character.Mounting concerns about drug-resistant have rekindled interest alternative treatments bacterial infections.Prominent among these alternatives phage...
Escherichia coli has eight genes predicted to encode sulfurtransferases having the active site consensus sequence Cys-Xaa-Xaa-Gly. One of these genes, ybbB, is frequently found within bacterial operons that contain selD, selenophosphate synthetase gene, suggesting a role in selenium metabolism. We show ybbB required vivo for specific substitution sulfur 2-thiouridine residues E. tRNA. This modified tRNA nucleoside, 5-methylaminomethyl-2-selenouridine (mnm(5)se(2)U), located at wobble...
Three-dimensional (3D) tumor spheroids are utilized in cancer research as a more accurate model of the vivo microenvironment, compared to traditional two-dimensional (2D) cell culture. The spheroid is able mimic effects cell-cell interaction, hypoxia and nutrient deprivation, drug penetration. One characteristic this development necrotic core, surrounded by ring G1 arrested cells, with proliferating cells on outer layers spheroid. Of interest field how different regions respond therapies...
Francisella tularensis is a zoonotic, Gram-negative coccobacillus that causes tularemia in humans and animals. F. subspecies (type A) holarctica B) are antigenically similar more virulent than novicida humans. The genetic locus encodes the LPS O antigen was found to be substantially different between type B live vaccine strain (LVS) novicida. One LVS-specific gene with homology galactosyl transferase selected for allelic replacement using sacB–chloramphenicol expression suicide plasmid,...
Every physical abnormal criterion has an impact on the health. Late menopause causes different physiological problems which alike early menopause. The research interest is associated with both and late menopausal women of Bangladesh as only few studies available in South East Asia especially Bangladesh. aims this study are not to assess symptoms abnormality but also determine these quality life (QOL) female society
Objectives:The aims of the research are to examine problems abnormal menopausal women: relationship between depression and menopausal-specific quality life (MENQOL)-symptoms among postmenopausal women; association MENQOL-symptoms pre-and female society in Bangladeshi real community.Methods: This cross sectional study was conducted on 435 women Tangail, aged (≥ 17) years, using a structured questionnaire where is inaacluded information MENQOL one main outcomes "depression" measured by beck...
Abstract Most BRAF ‐mutant melanoma patients experience a fulminate relapse after several months of treatment with BRAF/MEK inhibitors. To improve therapeutic efficacy, natural plant‐derived compounds might be considered as potent additives. Here, we show that magnolol, constituent Magnolia officinalis , induced G1 arrest, apoptosis and cell death in BRAF‐ NRAS‐ mutant cells at low concentration, no effect NRAS wild‐type human keratinocytes. This was confirmed 3D spheroid model. The...
Aim: To investigate the integrated epigenetic regulation of acquired drug resistance in cancer. Materials & methods: Our gene expression data five induced drug-tolerant cell models, one resistant line and publicly available drug-resistant dataset were to identify common differentially expressed genes pathways. ChIP-seq DNA methylation by HM450K beadchip used study profile differential genes. Results conclusion: Integrated transcriptomic analysis identified a 'viral mimicry' related signature...
Abstract Azadirachta indica (Neem) is very useful traditional medicinal plant in the subcontinent. Each part of tree has some properties. In this present studies bioactivity and antimicrobial activity leaf extract was evaluated. For bioactivity, Brine shrimp lethality test done for A. ethanolic determined LC50 37.15 μg/ml indicating that prepared rich bioactive compounds. Ethanolic also used to evaluate antibacterial exhibited significant against tested bacterial strain. However, inhibitory...
Background: The problem of cancer, especially lung is very acute in Bangladesh. present study was conducted to evaluate the risk cancer among Bangladeshi people based on hereditary, socio-economic and demographic factors. Materials Methods: This carried out 208 (patients-104, controls-104) from January 2012 September 2013 using a structured questionnaire containing details factors including smoking, secondhand smoke, tobacco leaf intake, age, gender, family history, chronic diseases,...
Three-dimensional (3D) tumor spheroids are utilized in cancer research as a more accurate model of the vivo microenvironment, compared to traditional two-dimensional (2D) cell culture. The spheroid is able mimic effects cell-cell interaction, hypoxia and nutrient deprivation, drug penetration. One characteristic this development necrotic core, surrounded by ring G1 arrested cells, with proliferating cells on outer layers spheroid. Of interest field how different regions respond therapies...
Background: Poisoning is a significant global public health problem. In many countries acute poisoning one of the common scenarios in emergency department any general hospitals globally but it’s pattern may vary different parts world and even be regional variation same country.Objective: this study our main goal to evaluate Profile cases attending Emergency Department Khwaja Yunus Ali Medical College & Hospital (KYAMCH), Enayetpur, Sirajganj.Materials Methods: This cross-sectional was...
Abstract Background Detection of minor DNA allele alterations is becoming increasingly important for early detection and monitoring cancer. We describe a new method that uses ultraviolet light to eliminate wild-type alleles enables improved genetic or epigenetic changes. Methods Pyrimidine-dependent UV-based minor-allele enrichment (PD-UVME) employed oligonucleotide probes incorporated UVA-sensitive 3-cyanovinylcarbazole (CNVK), placed directly opposite interrogated pyrimidines, such as...
Keywords: ABO blood group; RhD groupIbrahim Card Med J 2011; 1(1):33-35
201 Background: Monocyte chemoattractant protein 1 (CCL2 or MCP-1), a chemokine secreted by monocytic cells, is critical in recruiting T reg and MDSCs into the tumor microenvironment regulating prostate cancer (PCa) migration proliferation. In this study, we examined circulating CCL2 levels healthy vs PCa patients used an vitro coculture model to identify source of elevated CCL2. Methods: Serum concentrations were evaluated via ELISA 59 (19 health controls, 20 “treatment naïve” PCa, mCRPC)....