A5035172188- Cerebral Venous Sinus Thrombosis
- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Vascular Anomalies and Treatments
- Neurosurgical Procedures and Complications
- Extracellular vesicles in disease
- Vascular Malformations Diagnosis and Treatment
- Nanoplatforms for cancer theranostics
- Advanced Electron Microscopy Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Head and Neck Surgical Oncology
Chris O’Brien Lifehouse
2024
Royal Prince Alfred Hospital
2022-2024
Abstract Background Biomarkers that reflect glioblastoma tumour activity and treatment response are urgently needed to help guide clinical management, particularly for recurrent disease. As the urinary system is a major clearance route of circulating extracellular vesicles (EVs; 30–1000 nm nanoparticles) we explored whether sampling urinary-EVs could serve as simple non-invasive liquid biopsy approach measuring glioblastoma-associated biomarkers. Methods Fifty urine specimens (15–60 ml) were...
Background: Antiphospholipid syndrome is a complex autoimmune condition associated with the formation of recurrent thrombosis in any vascular bed throughout body. Jugular vein very rare only 0.9% occurrence and not typically cerebrospinal rhinorrhea as result raised intracranial pressure. Case Description: A 54-year-old patient presented 9-month history fluid (CSF) headache on background antiphospholipid syndrome. Investigations showed superior vena cava (SVC) right internal jugular (IJV)...
Dual antiplatelet therapy (DAPT) is standard treatment for endoluminal stent insertion, and complete resistance to DAPT rare. A case of in-stent thrombosis occurring 3 hours after stent-assisted coiling internal carotid artery aneurysm presented despite compliance with DAPT. Platelet function tests (PFTs) revealed clopidogrel prasugrel resistance.
Abstract BackgroundThere is increasing evidence to demonstrate the use and efficacy of venous sinus angioplasty in select patients with medically refractory idiopathic intracranial hypertension (IIH) stenosis. In challenging access, transcranial access may be required. MethodsWe describe novel technique open cranial for stenting that it safe effective appropriate candidate.Results ConclusionTranscranial IIH has not yet been described adult population. It utilises combined endovascular...