A5016093458- Neuroscience and Neuropharmacology Research
- Bioactive Compounds and Antitumor Agents
- Inflammatory mediators and NSAID effects
- Eicosanoids and Hypertension Pharmacology
- Ginseng Biological Effects and Applications
- Biological and pharmacological studies of plants
Xinjiang Medical University
2021
Fifth Affiliated Hospital of Xinjiang Medical University
2021
In this study, multivesicular liposomes (MVLs) were prepared by microfluidic technology and used for delivering gastrodin (GAS), a water-soluble drug, across the blood–brain barrier (BBB). The formulations preparation parameters in preparing (GAS-MVLs) both optimized. Some properties of GAS-MVLs including morphology, particle size, encapsulation efficiency, vitro release evaluated. An BBB model was established coculturing mouse brain endothelial cells (bEnd.3) astrocytes (C8-D1A)....
The present study was aimed to evaluate the chemopreventive potential of galangin against benzo(a)pyrene (BaP)-induced stomach carcinogenesis in Swiss albino mice. Stomach cancer induced experimental mice using BaP oral administration. were treated with (10 mg/kg b.wt.) before and during Oral administration at a dose 10 b.wt. significantly (p < 0.05) prevented tumor incidence, volume animals. Further, pretreatment prevents BaP-induced lipid peroxidation restores BaP-mediated loss cellular...