K R Poskitt

ORCID: 0000-0003-2037-108X
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About
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Research Areas
  • Diagnosis and Treatment of Venous Diseases
  • Venous Thromboembolism Diagnosis and Management
  • Aortic aneurysm repair treatments
  • Peripheral Artery Disease Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Wound Healing and Treatments
  • Pressure Ulcer Prevention and Management
  • Diabetic Foot Ulcer Assessment and Management
  • Aortic Disease and Treatment Approaches
  • Central Venous Catheters and Hemodialysis
  • Global Health Care Issues
  • Cerebrovascular and Carotid Artery Diseases
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Renal and Vascular Pathologies
  • Abdominal Surgery and Complications
  • Cardiac and Coronary Surgery Techniques
  • Pulmonary Hypertension Research and Treatments
  • Atrial Fibrillation Management and Outcomes
  • Gallbladder and Bile Duct Disorders
  • Dermatologic Treatments and Research
  • Vascular anomalies and interventions
  • Hernia repair and management
  • Thermoregulation and physiological responses
  • Cardiovascular Health and Disease Prevention
  • Vascular Procedures and Complications

Cheltenham General Hospital
2008-2021

Gloucestershire Hospitals NHS Foundation Trust
2018-2021

National Health Service
2020

Cheltenham Festivals
2000-2019

Addenbrooke's Hospital
2010

Gloucestershire Royal Hospital
2000-2009

Southmead Hospital
2009

Northern General Hospital
2003

University Hospitals Coventry and Warwickshire NHS Trust
2003

Hull Royal Infirmary
2003

The aim of this study was to evaluate the anatomical and haemodynamic effects superficial venous surgery compression on legs with chronic ulceration.Legs open or recently healed ulceration saphenous reflux were treated multilayer bandaging plus as part a clinical trial. Venous duplex imaging performed before treatment at 1 year. Legs stratified having no deep reflux, segmental total reflux. refill times (VRTs) calculated year using photoplethysmography, without narrow below-knee cuff...

10.1002/bjs.4837 article EN British journal of surgery 2004-12-06

<b>Objective</b> To determine whether recurrence of leg ulcers may be prevented by surgical correction superficial venous reflux in addition to compression. <b>Design</b> Randomised controlled trial. <b>Setting</b> Specialist nurse led ulcer clinics three UK vascular centres. <b>Participants</b> 500 patients (500 legs) with open or recently healed and reflux. <b>Interventions</b> Compression alone compression plus saphenous surgery. <b>Main outcome measures</b> Primary outcomes were healing...

10.1136/bmj.39216.542442.be article EN BMJ 2007-06-01

Venous disease is the most common cause of leg ulceration. Although compression therapy improves venous ulcer healing, it does not treat underlying causes hypertension. Treatment superficial reflux has been shown to reduce rate recurrence, but effect early endovenous ablation on healing remains unclear.

10.1056/nejmoa1801214 article EN New England Journal of Medicine 2018-04-24

Incisional herniation is a common complication of abdominal aortic aneurysm (AAA) repair. This study investigated whether prophylactic mesh placement could reduce the rate postoperative incisional hernia after open repair AAA.This randomized clinical trial was undertaken in three hospitals. Patients undergoing elective AAA were to routine mass closure or polypropylene preperitoneal plane.Eighty-five patients with mean age 73 (range 59-89) years recruited, 77 (91 per cent) whom men. There...

10.1002/bjs.7137 article EN British journal of surgery 2010-07-05

The aim was to assess healing in patients with mixed arterial and venous leg ulcers after protocol-driven treatment a specialist ulcer clinic.The study included consecutive referred ulceration reflux over 6 years. Legs without disease (ankle : brachial pressure index (ABPI) above 0.85) were treated multilayer compression bandaging severe (ABPI 0.5 or less) considered for immediate revascularization. Those moderate compromise up initially managed supervised modified revascularization if their...

10.1002/bjs.5757 article EN British journal of surgery 2007-05-11

Introduction The ESCHAR trial showed that superficial venous surgery and compression in chronic ulceration achieved a 24-week healing rate of 65% 12-month recurrence 12%. Foam sclerotherapy treatment is an alternative to surgery. aim this study assess the effect foam on ulcer leg ulcers. Methods Chronic ulcers (CEAP [clinical, aetiological, anatomical pathological elements] 5 CEAP 6) with reflux were treated between March 2006 June 2011 ultrasound-guided compression. Venous duplex was...

10.1258/phleb.2011.011118 article EN Phlebology The Journal of Venous Disease 2012-03-16

One-year outcomes from the Early Venous Reflux Ablation (EVRA) randomized trial showed accelerated venous leg ulcer healing and greater ulcer-free time for participants who are treated with early endovenous ablation of lower extremity superficial reflux.To evaluate clinical cost-effectiveness reflux in patients ulceration.Between October 24, 2013, September 27, 2016, EVRA enrolled 450 (450 legs) ulceration less than 6 months' duration reflux. Initially, 6555 were assessed eligibility, 6105...

10.1001/jamasurg.2020.3845 article EN cc-by JAMA Surgery 2020-09-23

Abstract Background Rupture of an unsuspected abdominal aortic aneurysm is a major cause death in men over the age 65 years. A significant reduction deaths likely to result only from higher rates detection and increased numbers elective repairs. Screening reaching years has been taking place county Gloucestershire, UK since 1990 aim this study was investigate any change mortality rate screened portion population. Methods Total number all aneurysm-related causes county's population calculated...

10.1046/j.1365-2168.2000.01476.x article EN British journal of surgery 2000-06-01

Screening for abdominal aortic aneurysm (AAA) has been carried out in Gloucestershire since 1990. All men the county are offered ultrasonography their 65th year. Men with an diameter of less than 26 mm considered 'normal' and no follow-up is arranged. The aim this study was to ascertain if diameters at age 65 years ever develop a clinically significant aneurysm.A cohort performed on 223 65-year-old who had aorta 1988. These repeat 1993 2000. causes death died during interval were...

10.1046/j.0007-1323.2001.01822.x article EN British journal of surgery 2001-07-01

The aim was to determine the optimum rescreening interval for small abdominal aortic aneurysms (AAAs).Data from 12 years of population screening 65-year-old men were analysed and 1121 AAAs (less than 4.0 cm in initial diameter) divided into groups: group 1 (2.6-2.9 cm; n = 625), 2 (3.0-3.4 330) 3 (3.5-3.9 166). Expansion rate cumulative proportions expand over 5.5 cm, or require surgery, rupture calculated.Expansion related diameter: 0.09 per year 1, 0.16 0.32 (P < 0.001). Aneurysms 2.4 cent...

10.1002/bjs.4216 article EN British journal of surgery 2003-07-01

10.1016/s1078-5884(98)80056-7 article EN publisher-specific-oa European Journal of Vascular and Endovascular Surgery 1998-10-01

Chronic venous ulcers are common, and even with effective compression or elevation large may take months to heal. Pinch skin grafting allow healing from epithelial islands throughout the surface area of ulcer, a prospective randomised trial was therefore conducted comparing this treatment porcine dermis dressings. Most patients were treated as outpatients, 25 being pinch grafts 28 dermis. Though groups well matched, mean rate in first week 15 cm2 for compared 3.5 (p less than 0.02). By life...

10.1136/bmj.294.6573.674 article EN BMJ 1987-03-14

Colour duplex ultrasonographic imaging has largely replaced venography in the assessment of lower-limb venous disorders. This is a study use management patients with chronic ulceration community ulcer clinics. Patients leg and an ankle: brachial pressure index 0.85 or greater were studied. Assessment competence both deep superficial systems affected unaffected legs was performed using colour imaging. Reflux defined as reverse flow for than 1 s after manual calf compression. One hundred...

10.1002/bjs.1800831016 article EN British journal of surgery 1996-10-01

The organization of leg ulcer care is poorly defined in the community. This study assessed overall influence a specialized community service on management and outcome chronic ulcers, irrespective aetiology.Assessment ulcers were compared patient samples (n = 200) from East West Gloucestershire, before after introduction clinics into Gloucestershire. In clinics, vascular disease was routinely by duplex scanning determination ankle : brachial pressure index.There no coordinated structure for...

10.1046/j.1365-2168.2000.01491.x article EN British journal of surgery 2000-08-01

Gloucestershire's screening project shows the potential benefits of a national programme and how it could be run Every year about 6000 men die from ruptured abdominal aortic aneurysm in England Wales. 1 Although this represents only 2% all deaths men, condition is largely preventable.It also disease that seems to increasingly prevalent, at least Scotland, despite fact other atherosclerotic conditions are reducing. 2This article explores requirements for programme, using as model...

10.1136/bmj.328.7448.1122 article EN BMJ 2004-05-06

To assess the outcome after transthoracic endoscopic sympathectomy (TES) for upper limb hyperhidrosis.Prospective cohort study.District general hospital.Consecutive patients undergoing TES hyperhidrosis over a fifteen month period.One-stage bilateral TES.Change in quality of life as shown by Short Form-36 health assessment questionnaire.Sixteen (11 women and 5 men, median age 26 years) underwent operation without complications. At follow-up 6.2 months, symptomatic improvement was found 32...

10.1080/11024159850191139 article EN The European Journal of Surgery 2002-07-26

Background Venous ulceration is a common and costly health-care issue worldwide, with poor healing rates greatly affecting patient quality of life. Compression bandaging has been shown to improve reduce recurrence, but does not address the underlying cause, which often superficial venous reflux. Surgical correction reflux reduces ulcer recurrence; however, effect early endovenous ablation on unclear. Objectives To determine clinical effectiveness cost-effectiveness compression therapy...

10.3310/hta23240 article EN publisher-specific-oa Health Technology Assessment 2019-05-01
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