A5001975585- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Peripheral Artery Disease Management
- Cardiovascular Health and Disease Prevention
- Cerebrovascular and Carotid Artery Diseases
- Aortic aneurysm repair treatments
- Infectious Aortic and Vascular Conditions
- Dermatologic Treatments and Research
- Central Venous Catheters and Hemodialysis
- Cardiac Imaging and Diagnostics
- Vascular Procedures and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Disease and Adiposity
- Abdominal vascular conditions and treatments
- Orthopedic Infections and Treatments
- Infective Endocarditis Diagnosis and Management
- Coronary Interventions and Diagnostics
- Connective tissue disorders research
- Cardiovascular Function and Risk Factors
- Diabetes Management and Research
- Patient Satisfaction in Healthcare
- Renal and Vascular Pathologies
- Acute Ischemic Stroke Management
- Pressure Ulcer Prevention and Management
Society for Vascular Surgery
2022-2023
Faculdade Novos Horizontes
2023
Ypsilanti District Library
2023
National Health Service
2020-2022
University of Padua
2022
Historical Society of Frankford
2022
Pallium India
2022
Northwick Park Hospital
2003-2020
London North West Healthcare NHS Trust
2003-2020
British Association of Urological Surgeons
2019
Venous disease is the most common cause of leg ulceration. Although compression therapy improves venous ulcer healing, it does not treat underlying causes hypertension. Treatment superficial reflux has been shown to reduce rate recurrence, but effect early endovenous ablation on healing remains unclear.
Topical oxygen has been used for the treatment of chronic wounds more than 50 years. Its effectiveness remains disputed due to limited number robust high-quality investigations. The aim this study was assess efficacy multimodality cyclical pressure Wound Oxygen (TWO2) home care therapy in healing refractory diabetic foot ulcers (DFUs) that had failed heal with standard (SOC) alone.Patients diabetes and DFUs were randomized (double-blind) either active TWO2 or sham control therapy-both...
Background Endovenous thermal ablation has revolutionised varicose vein treatment. New non-thermal techniques such as mechanical occlusion chemically assisted endovenous (MOCA) allow treatment of entire trunks with single anaesthetic injections. Previous non-randomised work shown reduced pain post-operatively MOCA. This study presents a multi-centre randomised controlled trial assessing the difference in during truncal using MOCA and radiofrequency (RFA) six months’ follow-up. Methods...
Objective Endovenous techniques are, at present, the recommended choice for truncal vein treatment. However, thermal require tumescent anaesthesia, which can be uncomfortable during administration. Non-tumescent, non-thermal would, therefore, have potential benefits. This randomised controlled trial is being carried out to compare degree of pain that patients experience while receiving mechanochemical ablation or radiofrequency ablation. The early results this are reported here. Methods...
Abstract Background Patients undergoing prolonged pelvic surgery may develop compartment syndrome of one or both lower limbs in the absence direct trauma pre-existing vascular disease (well leg syndrome). This condition have devastating consequences for postoperative recovery, including loss life limb, and irreversible disability. Methods These guidelines represent collaboration a multidisciplinary group colorectal, orthopaedic surgeons, acting on behalf their specialty associations UK...
One-year outcomes from the Early Venous Reflux Ablation (EVRA) randomized trial showed accelerated venous leg ulcer healing and greater ulcer-free time for participants who are treated with early endovenous ablation of lower extremity superficial reflux.To evaluate clinical cost-effectiveness reflux in patients ulceration.Between October 24, 2013, September 27, 2016, EVRA enrolled 450 (450 legs) ulceration less than 6 months' duration reflux. Initially, 6555 were assessed eligibility, 6105...
Abstract Plasmacytoid dendritic cells (PDC) constitute a distinct subset of DC found in human peripheral lymph nodes (LN), but little is known about their function. Cell suspensions were prepared from tumor draining LN (n=20) and control (n=11) women undergoing surgical resection for primary breast cancer elective surgery benign conditions, respectively. Using four-color flow cytometry, leukocyte antigen-DR+ subsets identified phenotypically. The proportions numbers innately producing...
Abstract Background Vascular surgical care has changed dramatically in recent years with little knowledge of the impact system failures on patient safety. The primary aim this multicentre observational study was to define landscape failures, errors and inefficiency (collectively termed failures) aortic surgery. Secondary aims were investigate determinants these their relationship outcomes. Methods Twenty vascular teams at ten English hospitals trained structured self-reporting intraoperative...
Background Venous ulceration is a common and costly health-care issue worldwide, with poor healing rates greatly affecting patient quality of life. Compression bandaging has been shown to improve reduce recurrence, but does not address the underlying cause, which often superficial venous reflux. Surgical correction reflux reduces ulcer recurrence; however, effect early endovenous ablation on unclear. Objectives To determine clinical effectiveness cost-effectiveness compression therapy...
Abstract Background Treatment of superficial venous reflux in addition to compression therapy accelerates leg ulcer healing and reduces recurrence. The aim this study was evaluate the costs cost-effectiveness early versus delayed endovenous treatment patients with ulcers. Methods This a within-trial cost-utility analysis 1-year time horizon using data from EVRA (Early Venous Reflux Ablation) trial. compared deferred ablation for truncal ulcer. outcome measure cost per quality-adjusted...
Arterial ultrasonic appearances using high resolution ultrasound were studied in 97 subjects with Type 2 diabetes and age‐ sex‐matched controls. The intima‐media thickness of both common carotid arteries was measured cm proximal to the bifurcation presence or absence plaque on femoral bifurcations recorded. mean 0.82 ± 0.22 mm while controls 0.66 0.13 ( p < 0.001). Multiple regression diabetic only showed no correlation between age, sex, body mass index, smoking, duration diabetes,...
The aim of this study was to demonstrate whether HR (Paroven-Venoruton; 0-(β-hydroxyethyl)-rutosides), effective in improving the microcirculation venous hypertension and microangiopathy. Sixty patients with severe due chronic insufficiency, ankle swelling, lipodermatosclerosis were included. After informed consent, randomized into a treatment group placebo group. Patients received oral (2 g/day for 8 weeks); those comparable placebo. Results: two groups age sex distribution. mean 45 years...
Noninvasive ultrasonic biopsy (UB) is a method of detecting early arteriosclerotic changes by high-resolution ultrasound scanning the carotid and femoral bifurcation. Six UB classes (scoring 0 to 10) have been identified in 2000 asymptomatic subjects 600 vascular patients followed up for four years. The incidence silent coronary ischemia (tested effort test) occurrence symptomatic events years are increased advanced with increasing score. rate progression (ROP) next class has defined normal...
Objectives: The aim of this study was to demonstrate whether and how HR (Venoruton 1000 , Paroven, 0-[beta-hydroxyethyl]-rutosides) Daflon (diosmin, 500 mg) were comparatively effective in improving the microcirculation venous hypertension microangiopathy. Methods: A group 90 patients with severe due chronic insufficiency, ankle swelling, lipodermatosclerosis included. After informed consent, randomized into a Venoruton (DF) group: received oral (2 g/day for 8 weeks); those three 500-mg...