A5047736073- Opioid Use Disorder Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Patient Satisfaction in Healthcare
- Pain Management and Opioid Use
- Prenatal Substance Exposure Effects
- Substance Abuse Treatment and Outcomes
- Maternal Mental Health During Pregnancy and Postpartum
- Orthopaedic implants and arthroplasty
- Hormonal and reproductive studies
- Anesthesia and Pain Management
- Cannabis and Cannabinoid Research
- Peripheral Artery Disease Management
- Global Cancer Incidence and Screening
- Healthcare Policy and Management
- Pharmaceutical Economics and Policy
- Total Knee Arthroplasty Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Inflammatory mediators and NSAID effects
- Adrenal Hormones and Disorders
- Venous Thromboembolism Diagnosis and Management
- Diabetes Treatment and Management
- Statistical Methods in Clinical Trials
- Economic and Financial Impacts of Cancer
- Prostate Cancer Diagnosis and Treatment
- Musculoskeletal pain and rehabilitation
University of Arkansas for Medical Sciences
2016-2025
Center for Drug Evaluation and Research
2024
United States Food and Drug Administration
2021-2024
Center for Devices and Radiological Health
2021-2023
University of York
2023
University of Maryland, College Park
2023
University of Maryland, Baltimore
2018-2021
Central Arkansas Veterans Healthcare System
2017
Abstract Benzodiazepines and opioids are commonly used among veterans suffering from mental health disorders pain conditions. The objective of this study is to determine whether concomitant benzodiazepine-opioid use increases the incidence adverse outcomes above baseline risk nonacute opioid-only use. dataset contained all who filled at least 1 opioid prescription during years 2008 2012. Nonacute was defined as having prescriptions greater than or equal 20 days within a 60-day period....
Background: Oral NSAIDs are widely used analgesic medications for the treatment of musculoskeletal and inflammatory conditions. associated with adverse effects that arise from COX enzyme inhibition including cardiovascular events. The combined role patient prescription factors NSAID use on risk is not well characterized. Objective: purpose this study to identify events among users. Methods: This a retrospective, nested case–control study, within DAVINCI database, active-duty service members...
Introduction: This study aimed to analyze opioid prescribing behavior following surgical interventions for benign prostatic hyperplasia (BPH), focusing on differences in postoperative practices between patients who undergo procedures operative room (OR) settings vs. non-operative (non-OR) settings. Methods: A retrospective cohort was conducted using a 10% random sample of the IQVIA PharMetrics® Plus Academics database, including men underwent BPH from 2015–2020. Propensity score analysis and...
This study addresses the critical need for an evidence-based instrument to assess likelihood of NSAID-induced cardiovascular events, that provides clinicians with valuable decision support improve safety in their use pain management, especially patients vulnerable events. To develop a practical risk scoring tool, NSAID Induced Cardiovascular Events (NAÏVE), estimating serious events associated use. Retrospective nested case-control study. The leveraged data from DAVINCI database, integrating...
Inadequate treatment of opioid use disorder (OUD) in pregnant women increases the risk life-threatening consequences on maternal and fetal outcomes. Untreated OUD during pregnancy is associated with higher rates adverse outcomes among newborns.To examine variation prevalence medication-assisted commercially insured according to region state legislature.Cohort study which patient cohort used was derived from a 10% random sample enrollees within IQVIA PharMetrics Plus adjudicated claims...
These analyses examined opioid initiation and chronic use among Iraq (OIF) Afghanistan (OEF/OND) veterans with a new diagnosis of traumatic brain injury (TBI) in the Veterans Health Administration (VHA).Data were obtained from national VHA data repositories. Analyses included OEF/OIF/OND TBI 2010-2012 who used at least twice, had not received prescription 365 days before diagnosis, available after diagnosis.Analyses 35,621 veterans. Twenty-one percent initiated opioids; initiators, 23%...
Objectives: To identify and define potential positive negative factors in patient experiences patient-provider interactions that are associated with the pursuit maintenance of treatment by those suffering from substance use disorders (SUD).Methods: Two focus groups patients for SUD were performed. The focused on questions aimed at mapping initiating maintaining along transtheoretical model change. Four in-depth interviews healthcare providers involved also conducted to understand providers'...
The objective of this study was to identify the trajectories that patients take after initiating long-term opioid therapy (LTOT).Using a retrospective cohort design, veterans with chronic non-cancer pain (CNCP) LTOT were identified. Group-based trajectory models used based on days supply (primary outcome) and average daily morphine milligram equivalent dose (AMME; secondary in each 180-day period following initiation LTOT.A total 438,398 CNCP initiated LTOT. Nine identified: 33.7%...
Stakeholders increasingly expect research and care delivery to be guided by optimize patient experiences. However, standardized tools engage patients gather high-quality data about their experiences, priorities, desired outcomes are not publicly available. The objective of this study was develop test a Toolbox with disease-agnostic interview guide template accompanying resources assist researchers in engaging living chronic disease dialogue Guided multidisciplinary workgroup, targeted...
Medications play a critical role supporting the health of military service members. Little is known about broad use medications prescribed to this population. Active duty members (ADSMs), while often younger and having fewer diagnosed comorbid conditions, face unique challenges that benefit from pharmacotherapy. Understanding prescribing patterns instrumental illuminate potential areas for research guide education so care professionals can maintain competency, improve outcomes, support...
Introduction: The COVID-19 pandemic has led to the rapid and widespread adoption of telehealth services. Telehealth may aid in bridging gaps access care. specific impact on opioid use disorder (OUD) its treatment remains uncertain.
Abstract Purpose We identified associations between membership in seven group‐based trajectories based on supply of filled opioid prescriptions and potential opioid‐related adverse health events over a 720‐day window. Methods two veteran cohorts with chronic non‐cancer pain who initiated treatment long‐term therapy 2008 2015, excluding those prior substance use disorder ( n = 373 941) or non‐SUD, outcome 405 631) diagnoses. Outcomes interest included disorder, non‐opioid drug alcohol for the...
A multistakeholder expert group under the Women's Health Technology Coordinated Registry Network (WHT-CRN) was organized to develop foundation for national infrastructure capturing performance of long-acting and permanent contraceptives. The group, consisting representatives from professional societies, US Food Drug Administration, academia, industry patient community, assembled discuss role feasibility CRN identify core data elements needed assess contraceptive medical product technologies....
<h3>Importance</h3> The worldwide population is aging and includes more female individuals than male individuals, with higher rates of total hip arthroplasty (THA) among individuals. Although research on this topic has been limited to date, several studies are currently under way. <h3>Objectives</h3> To evaluate the association between sex 2-year revision after THA. <h3>Design, Setting, Participants</h3> This cohort study used data from statewide databases in New York California October 1,...
Conflicting reports from varying stakeholders related to prognosis and outcomes following placement of temporomandibular joint (TMJ) implants gave rise the development TMJ Patient-Led RoundTable initiative. Following an assessment current availability data, concluded that a strategically Coordinated Registry Network (CRN) is needed collect generate accessible data on disorder (TMD) its care. The aim this study was therefore advance clinical understanding, usage, adoption core minimum dataset...
Abstract Background The effectiveness of combined atherectomy and stenting relative to use each procedure alone for the treatment lower extremity peripheral artery disease has not been evaluated. Aims objective this study was evaluate short‐ long‐term major adverse limb event (MALE) following receipt stenting, atherectomy, combination stent atherectomy. Methods A retrospective cohort patients undergoing stent, derived from Vascular Quality Initiative (VQI) data set. primary outcome MALE...
This study aims to assess the patient-centeredness and psychometric properties of Defense Veterans Pain Rating Scale 2.0 (DVPRS) as a patient-reported outcome measure (PROM) for pain assessment in military population.