- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Hemodynamic Monitoring and Therapy
- Vitamin K Research Studies
- COVID-19 Impact on Reproduction
- Airway Management and Intubation Techniques
- Pharmacology and Obesity Treatment
- Vitamin C and Antioxidants Research
- COVID-19 and healthcare impacts
- Diet and metabolism studies
- Neuroscience of respiration and sleep
- Cardiac and Coronary Surgery Techniques
- Cardiac Ischemia and Reperfusion
- Healthcare cost, quality, practices
- Cardiac Arrhythmias and Treatments
- Electrolyte and hormonal disorders
- Adrenal Hormones and Disorders
- Mechanical Circulatory Support Devices
- Atrial Fibrillation Management and Outcomes
- COVID-19 and Mental Health
Ospedale San Carlo
2023
Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo
2023
Istituti di Ricovero e Cura a Carattere Scientifico
2017-2022
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2017-2022
Vita-Salute San Raffaele University
2017-2022
Aziende Socio Sanitarie Territoriale dei Sette Laghi
2022
Ospedale di Circolo e Fondazione Macchi
2022
IRCCS Ospedale San Raffaele
2020
Xavier Elharrar, MD; Youssef Trigui, Anne-Marie Dols, François Touchon, Stéphanie Martinez, Eloi Prud'homme, Laurent Papazian, MD, PhD
At the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak spread from China all around world, causing thousands deaths. In Italy, hardest hit region was Lombardy, with first reported case on 20 February 2020. San Raffaele Scientific Institute — a large tertiary hospital and research centre in Milan, Italy immediately involved management public health emergency. Since beginning outbreak, elective surgical activity rapidly reduced areas were simultaneously...
Non-intubated patients with acute respiratory failure due to COVID-19 could benefit from awake proning. Awake proning is an attractive intervention in settings limited resources, as it comes no additional costs. However, remains poorly used probably because of unfamiliarity and uncertainties regarding potential benefits practical application. To summarize evidence for develop a set pragmatic recommendations pneumonia, focusing on where resources are limited, international healthcare...
Background: In the first wave of novel coronavirus (severe acute respiratory syndrome 2) infections, Italy experienced a heavy burden hospital admissions for distress syndromes associated with disease (COVID-19). Early evidence suggested that females are less affected than males. Objective: This study aimed to assess gender-related differences in presentation and severity among COVID-19 patients admitted IRCCS San Raffaele Hospital, Milan, Italy. Materials Methods: prospective observational...
The coronavirus disease 2019 (COVID-19) pandemic has caused disruption in health systems all over the world. A considerable number of patients with COVID-19 need mechanical ventilation. It is therefore anticipated that there will be a surge requiring respiratory support and may shortfall devices available.
Objective: The use of angiotensin II in invasively ventilated patients with coronavirus disease 2019 (COVID-19) is controversial. Its effect on organ function unknown. Design: Prospective observational study. Setting: Intensive care unit (ICU) a tertiary academic hospital Milan, Italy. Participants: Adult receiving mechanical ventilation due to COVID-19. Interventions: Use either as rescue vasopressor agent or low dose support. Main outcome measures: Patients treated before was available an...
Background: Percutaneous left atrial appendage occlusion (LAAO) is indicated in subjects with fibrillation who cannot receive oral anticoagulants.This procedure requires transesophageal echocardiography guidance and usually performed under general anesthesia.The Janus Mask a new device designed to allow upper endoscopic procedures during noninvasive ventilation (NIV).Aims: This study aims assess the possibility of performing LAAO sedation NIV.Setting: Cardiac electrophysiology...
BACKGROUND: The aim of this study is to compare patients receiving continuous positive airway pressure through helmet and sedation in prone position outside the intensive care unit during first second outbreak waves Coronavirus disease 2019 (COVID-19).METHODS: Design: observational study. Setting: intermediate-care a teaching hospital. Patients: 17 consecutive affected by acute respiratory failure due COVID-19 distress syndrome. Intervention: was delivered non-intensive setting following...
Abstract Background: The use of angiotensin II (ANGII) in invasively ventilated COVID-19 patients is controversial. Its effect on markers organ function unknown. Methods : We used ANGII either as rescue vasopressor agent or low dose support. Patients treated before availability an adjacent ICU served controls. For data analysis, we applied Bayesian modelling appropriate. assessed the effects ANG function. Results compared 46 with 53 Compared controls, increased MAP (median difference, 9.05...