A5001513015- Cancer Research and Treatments
- Mesenchymal stem cell research
- Renal Transplantation Outcomes and Treatments
- Cancer Cells and Metastasis
- Pharmacological Effects and Toxicity Studies
- Pregnancy and preeclampsia studies
- Neurological Complications and Syndromes
- Tissue Engineering and Regenerative Medicine
- Wound Healing and Treatments
- Cancer-related gene regulation
- Trace Elements in Health
- Cancer Treatment and Pharmacology
- Ubiquitin and proteasome pathways
- Liver Disease and Transplantation
- Pregnancy and Medication Impact
- Gestational Diabetes Research and Management
- RNA modifications and cancer
- Congenital heart defects research
- Pharmacological Effects of Medicinal Plants
- Mechanisms of cancer metastasis
- Liver physiology and pathology
- Skin Protection and Aging
- Heat shock proteins research
- interferon and immune responses
- Blood Pressure and Hypertension Studies
Vietnam Military Medical University
2011-2022
Donghua University
2019
People's Liberation Army Air Force
2014
Air Force General Hospital PLA
2014
Institute for Transfusion Medicine
2014
Wuhan No.1 Hospital
2013
Qinhuangdao Second Hospital
2013
Breast cancer stem cells (BCSCs) are the source of breast tumors. Compared with other cells, show high resistance to both chemotherapy and radiotherapy. Targeting BCSCs is thus a potentially promising effective strategy for treatment. Differentiation therapy represents one type stem-cell-targeting therapy, aimed at attacking stemness reducing their chemo- radioresistance. In previous study, we showed that down-regulation CD44 sensitized anti-tumor agent doxorubicin. This study determine if...
Vascular endothelial growth factor (VEGF) is involved in the of new blood vessels that feed tumors and kinesin spindle protein (KSP) plays a critical role mitosis involving cell proliferation. Simultaneous silencing VEGF KSP, an attractive viable approach cancer, leads on restricting cancer progression. The purpose this study to examine therapeutic potential dual gene targeted siRNA cocktail human hepatocellular carcinoma Hep3B cells. predesigned siRNAs could inhibit KSP at mRNA level....
Stem cell therapy for the treatment of vascular-related diseases through functional revascularization is one most important research areas in tissue engineering. The aim this study was to investigate vitro differentiation umbilical CL-MSC into endothelial lineage cells.In study, isolated cells were characterized expression MSC-specific markers and osteogenic adipogenic differentiation. They induced differentiate endothelial-like then examined endothelial-specific markers, karyotype, behavior...
This study aims to investigate the anti-hypertensive effects of aqueous extract Callisia fragrans and their underlying mechanism using a two-kidney one-clip (2K1C) model reno-vascular hypertension in rats.The hypertensive rats were treated with C. leaf (100 500 mg/kg; p.o.) reference drug, captopril (20 p.o.), for 4 weeks. The blood pressure heart rate recorded tail-cuff. weight, left ventricular wall thickness, serum creatinine urea levels measured. A spectrophotometric assay was used...
Background . Mesenchymal stem cells (MSCs), isolated from bone marrow, adipose tissue, and umbilical cord have been known to differentiate into hepatocyte-like cells. MSCs can also be easily obtained lining membrane (CLMSCs). CLMSCs are more primitive than those other tissue sources. Objectives The aim of this study was investigate the in vitro differentiation hepatocyte lineage. Materials Methods In study, were through a attachment method. Cells characterized for expression MSC-specific...
For the surgical treatment of coronary artery disease, renal stenosis and other peripheral vascular there is a significant demand for small diameter (inner < 6 mm) grafts. However, autologous grafts are not always available when substitute severely diseased. In our previous work, hybrid small-diameter were successfully fabricated by combining electrospun polycaprolactone (PCL) decellularized rat aortas (DRA). histological assessments revealed development intimal hyperplasia, indicating...
Background: Kidney recipients often use a calcineurin inhibitor and proliferation after transplantation. The therapeutic drug monitoring for is more simple feasible in clinical than inhibitor. In Vietnam, mycophenolic acid popular used transplantation patients. Although so important treating kidney transplantation, the still difficult to execute Vietnam. Objectives: This study aimed determine MPA concentration on Vietnamese renal transplant recipients. Methods: observational was conducted 35...
Introduction : Immunological monitoring could indirectly measure the suppressive effects of drugs and provide early guidance on necessary preventive interventions in transplant recipients. Objectives Our goal was to determine whether mycophenolic acid (MPA) modulates peripheral blood lymphocyte T kidney Patients Methods We assessed lymphocytes CD3, CD4 CD8 30 donors 35 recipients one day before 10 days after transplantation using Becton Dickinson’s direct immune fluorescent light. Results...
Urease inhibition with oral antibodies is a promising strategy in the treatment of Helicobacter pylori infection.This study aimed to investigate advantages producing method anti-urease IgY and its inhibitory effect on H. infection experimental animal.We started process preparation Pylori's urease.Then eggs from hens that were immunized prepared urease collected be used for extraction.We divided 18 Swiss albino mice into 2 groups test IgY.One group was fed food containing other not.In end,...