A5070454479- Cytomegalovirus and herpesvirus research
- Pneumocystis jirovecii pneumonia detection and treatment
- Herpesvirus Infections and Treatments
- Pediatric health and respiratory diseases
- Immunodeficiency and Autoimmune Disorders
- HIV, TB, and STIs Epidemiology
- Respiratory and Cough-Related Research
- Respiratory viral infections research
- Parvovirus B19 Infection Studies
- Polyomavirus and related diseases
- Toxoplasma gondii Research Studies
- Viral Infections and Immunology Research
- Legionella and Acanthamoeba research
- Hepatitis Viruses Studies and Epidemiology
- Hepatitis C virus research
- Infectious Diseases and Tuberculosis
- T-cell and Retrovirus Studies
- Dermatological and COVID-19 studies
- Bartonella species infections research
- Yersinia bacterium, plague, ectoparasites research
- Bacillus and Francisella bacterial research
- Blood disorders and treatments
- Infectious Encephalopathies and Encephalitis
- Hepatitis B Virus Studies
- Hematological disorders and diagnostics
Gamalei Institute of Epidemiology and Microbiology
2015-2024
Ministry of Health of the Russian Federation
2019-2024
National Research Centre
2018
Institute of Epidemiology, Disease Control and Research
2015
Objective. The aim of the study is to investigate peculiarities changes in immune status individuals with active and latent forms herpesvirus infections. Herpesvirus infections are an urgent problem modern health care.
 Materials methods. prospective longitudinal cohort included 92 permanent blood donors who were examined twice at 6-month intervals for presence specific IgM IgG antibodies antigens herpes simplex viruses 1, 2, Epstein-Barr, cytomegalovirus, human type 6, as well humoral...
The article is devoted to study the etiological role of herpes viruses in infectious and somatic pathology children (n = 770) using complex methods laboratory diagnostics. Determined leading HSV with neuroinfections (12,7%) during primary infection intrauterine (29,0%) its reactivation. It shown that 50,9% cases, diagnosis «infectious mononucleosis» confirmed by detection markers acute EBV-infection, 20,0%, it was replaced mononucleotides syndrome discovered CMV-infection, 18,1% —...
The paper presents the results of comprehensive examination and treatment in 514 children who have developed a persistent cough lasting for more than 3 weeks after acute respiratory disease. cause coughing was concurrence infectious somatic diseases majority cases (62.8%). Among diseases, there were most common allergic organs (32.4%) ENT (27.4%). 311 (60.5%) found to markers Mycoplasma (43.9%), herpesvirus (42.2%), Pneumocystis (21.4%), Chlamydia (6.25%) infections as mono- or mixed...
The purpose of the study To estimate prevalence markers herpesvirus infections and pneumocystosis in patients hematological department. identify whether contamination with hepatitis B C (HBV, HCV) affects on activation opportunistic (OIs). Materials methods There were examined 94 department, including 48 HBV infection 46 cases without them. Obtained results Markers acute OIs (simple herpes virus type 1- 6,4%, EBV - 14,9%, CMV Human Herpesvirus 6- 13,8% 33,0% pneumocystosis) determined more...
The article presents the role of herpesviral infections caused by herpes simplex virus (HSV), Epstein-Barr (EBV), cytomegalovirus (CMV) and human herpesvirus type 6 (HHV-6) in 36 children with recurrent respiratory tract diseases at age from 1 to 18 years. Blood sera blood cells were studied using ELISA, Indirect reaction immunofluorescence Rapid culture method. It was found that all (100%) infected HSV, EBV, CMV HHV-6. Most often — 19 (52.8%) signs active HHV-6 revealed. In same number...
The article presents an interesting case of congenital infection pneumocystis conclusively proven and confirmed by various methods laboratory diagnostics, including morphological with a special color. In addition, parents were surveyed, which the source infection. Congenital pneumonia, especially in preterm infants, are direct threat to life. this regard, timely examination mother child, as well appointment etiotropic antibacterial drugs is important task prevent fatal outcome disease.
Human herpes virus type 6 (HHV-6) is the etiological agent of plenty diseases. The form developing pathology depends on localization in T-lymphocytes and type: HHV-6A or HHV-6B, but identification possible by nucleotide sequence only. In Russia, researching typing HHV-6 are conducted Moscow St. Petersburg mainly, results discordant. Also prevalence HHV-6B among various population groups particular interest.
The study is devoted to the clinical examination of frequently ill children in North-Eastern regions Russia and laboratory detection markers herpesvirus infections, as well pneumocystosis establishment relationship with their immune status. 62 aged 8—15 years were examined. Samples serum blood cells, sputum on infections by ELISA, indirect immunofluorescence reaction rapid culture method studied. Assessment humoral immunity determination circulating complexes was performed solid-phase enzyme...
Aim . To investigate the species composition and frequency of opportunistic pathogens in cancer patients diagnosed with non-small cell lung (NSCLC) receiving chemotherapeutic treatment at Federal State Budgetary Institution National Medical Research Center Oncology named after N. Blokhin Russian Ministry Health. Materials methods A prospective open single-center study included a cohort locally advanced or metastatic NSCLC drug antitumor therapy, aged 18 years older. The was observational...
Objective. To evaluate the involvement of P. jirovecii in infectious and other diseases children adults with immunosuppression various origin. assess risk infection jirovecii, pneumocystosis its spread by healthcare workers. Materials Methods. An analysis results a study 1,446 samples peripheral blood sera from patients, both adults, who were treated hospitals profiles Moscow represented an increased group for pneumocystosis. IgM IgG class antibodies determined enzyme immunoassay (ELISA)....
The study showed a high prevalence of markers herpesvirus infections among mothers — from 71% to 98% HSV, EBV and CMV 29% 58% HHV-6 infection. HSV remains the most common etiological agent intrauterine herpesviruses active infection caused by this virus were found in 28.3% samples. difficulty determining source absence data early stages pregnancy is presented on 4 out 10 cases Markers pneumocystic detected only mothers: group with children under age 21 days 21—27% cases, aged 22 28 15—21%....
The value of human herpes virus type 6 (HHV-6) in the structure seizures 114 children three groups patients: with neuroinfections, epilepsy and febrile convulsions was studied. Determination HHV-6 by polymerase chain reaction acute period disease is a reliable sign (p < 0.001), most often diagnosed group (53.8%). Recovery caused HHV-6, observed only 28% cases,38.8% patients outcome expand epilepsy.
127 children with long subfebrile have been eхamined. The causative role of active herpes virus infection in the etiology states has proved 36,7% cases. frequency detection acute (6,3%), reactivaited (30,4%) and latend (63,3%) forms infections conditions demonstrated. Prevalence mixed (78%) over mono-infection (22%) etiological structure revealed.
This article covers the issues of pathogenesis, diagnostics, clinical manifestations and treatment CMV infections at perinatal infection
Convulsive disorder frequently poses a great danger. The authors distinguish three groups of children who most often have convulsions. Those are «febrile» convulsions, convulsions that accomapny neuroinfections and epilepsy. Male gender age under 1 year early predictors «Febrile» Convulsions accompanying epilepsy manifest later. In 64,6 % the main role belongs to herpesviruses, especially from group CMV G6 type. When child with is accepted in-patient hospital, complex comprehensive...
Objective. To determine the detection rates of HHV-6A and HHV-6B compared to other herpes viruses in children different age groups. Materials Methods. A total 128 patients with symptoms respiratory viral infections (RVI) aged from 1 16 years 101 otherwise healthy children. comprehensive examination patients, including ELISA, indirect immunofluorescence assay, rapid culture method, PCR, determination nucleotide sequences HHV-6 was performed. Children positive for markers (antibodies, early...
Infections occupy one of the central places among complications transplants. The frequency fatal infectious during first twelve months after transplantation ranges from 2.6 to 51.7%. Identifying markers opportunistic infections before will help reduce likelihood developing these induced immunosuppression. aim study was role herpesviruses and pneumocysts in occurrence children liver based on detection a number herpesvirus pneumocystosis. article presents results comprehensive examination for...
The paper presents the results of comprehensive examination and treatment in 514 children who have developed a persistent cough lasting for more than 3 weeks after acute respiratory disease. cause coughing was concurrence infectious somatic diseases majority cases (62.8%). Among diseases, there were most common allergic organs (32.4%) ENT (27.4%). 311 (60.5%) found to markers Mycoplasma (43.9%), herpesvirus (42.2%), Pneumocystis (21.4%), Chlamydia (6.25%) infections as mono- or mixed...