A5055405628- Physical Activity and Health
- Obesity, Physical Activity, Diet
- Gestational Diabetes Research and Management
- Mobile Health and mHealth Applications
- Child and Adolescent Health
- Behavioral Health and Interventions
- Exercise and Physiological Responses
- Bariatric Surgery and Outcomes
- Pregnancy-related medical research
- Cardiovascular Effects of Exercise
- Animal Disease Management and Epidemiology
- Injury Epidemiology and Prevention
- Veterinary Equine Medical Research
- Health and Lifestyle Studies
- Tendon Structure and Treatment
- Sports injuries and prevention
- Cardiovascular and exercise physiology
- Inclusion and Disability in Education and Sport
- Musculoskeletal Disorders and Rehabilitation
- ATP Synthase and ATPases Research
- Lower Extremity Biomechanics and Pathologies
- Delphi Technique in Research
- Plant Toxicity and Pharmacological Properties
- Clinical Laboratory Practices and Quality Control
- Geriatric Care and Nursing Homes
Auckland University of Technology
2025
Physiotherapy New Zealand
2025
Sheffield Hallam University
2021-2023
Nuffield Orthopaedic Centre
2000-2022
Oxford University Hospitals NHS Trust
2019-2022
University of Oxford
2015-2019
British Heart Foundation
2016
Oxford Brookes University
2016
University of Edinburgh
2016
Background Recent investigation of human tissue and cells from positional tendons such as the rotator cuff has clarified importance inflammation in development progression tendon disease. These mechanisms remain poorly understood disease energy-storing Achilles. Using biopsies patients, we investigated if is a feature Achilles tendinopathy rupture. Methods We studied symptomatic patients with either mid-portion or rupture for evidence abnormal inflammatory signatures. Tendon-derived stromal...
Introduction The benefits of physical activity for people living with long-term conditions (LTCs) are well established. However, the risks less documented. fear exacerbating symptoms and causing adverse events is a persuasive barrier to in this population. This work aimed agree clear statements use by healthcare professionals about medical LTCs through expert consensus. These addressed following questions: (1) Is increasing safe one or more LTC? (2) Are clinical syndromes associated common...
Background/Aim: Previous reports have associated the KMT2A-ELL fusion gene, generated by t(11;19)(q23;p13.1), with acute myeloid leukemia (AML). We herein report a and novel ZNF56-KMT2A genes in pediatric T-lineage lymphoblastic (T-ALL). Materials Methods: Genetic investigations were performed on bone marrow of 13-year-old boy diagnosed T-ALL. Results: A der(11)t(11;19)(q23;p13.1) der(19)t(11;19)(q23;p13.1), respectively. Exon 20 KMT2A fused to exon 2 ELL chimeric transcript whereas 1 ZNF56...
Physical activity (PA) interventions are an important but underutilised component in the management of gestational diabetes mellitus (GDM). The challenge remains how to deliver cost effective PA that have impact on individual behaviour. Digital technologies can support and promote remotely at scale. We describe development a behaviourally informed smartphone application (Stay-Active) for women attending NHS GDM clinic. Stay-Active will existing motivational interviewing intervention increase...
The WHO has called for action to integrate physical activity promotion into healthcare settings, yet there is a lack of consensus on the competencies required by health professionals deliver effective movement behaviour change support. objective this study was establish key relevant all support individuals their behaviours. Consensus obtained using three-phase Delphi process. Participants with expertise in and sedentary were asked report what knowledge, skills attributes they believed should...
Resolution of inflammation is poorly understood in Achilles tendon disorders. Herein, we investigated the bioactive lipid mediator profiles tendon-derived stromal cells isolated from patients with tendinopathy (AT) or rupture (AR) under baseline and IL-1β–stimulated conditions. We also determined whether incubating these 2 mediators produced by cells, 15-epi-Lipoxin A4 (15-epi-LXA4) maresin (MaR)-1, moderated their proinflammatory phenotype. Under conditions, AT showed concurrent increased...
Our recent BJSM editorial petitioned for ‘a time action’ regarding physical activity (PA) and pregnancy guidance in the UK.1 We highlighted that despite providing a unique opportunity to promote PA behaviour change,2 healthcare professionals (HPs) lack confidence, knowledge resources deliver appropriate advice. They feel under-resourced, uncertain safety concerns inadequately trained.3 Consequently, being receptive advice, pregnant women receive inconsistent, vague conflicting guidance.4...
Objectives Healthcare is a fundamental action area in population efforts to address the global disease burden from physical inactivity. However, healthcare professionals lack knowledge, skills and confidence have regular conversations about activity. This study aimed to: (1) understand requirements of patients resource support routine activity clinical consultations (2) develop such resource. Methods used codesign principles across two phases, actively involving relevant stakeholders an...
Background In 2017 Public Health England and Sport commissioned a Consultant-led Exercise Medicine (SEM) pilot to test the feasibility acceptability of embedding physical activity interventions in secondary care clinical pathways. The aim this paper is report qualitative findings exploring experience healthcare professionals (HCPs) patients involved Active Hospital pilot. Methods Qualitative data was collected by semi-structured interviews with SEM Consultants, staff three Interviews...
Regular physical activity improves glycaemic control in pregnant women with gestational diabetes. Motivational interviewing is an effective technique for increasing levels. This report evaluates a clinical pathway developed to integrate motivational into routine diabetes care. Women attending single-centre NHS clinic were invited engage activity-focused interview. The aerobic levels of 62 evaluated at baseline and 2-week telephone follow up, coded three categories by minutes moderate...