A5101635882- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Allelopathy and phytotoxic interactions
- Parasitic Infections and Diagnostics
- Microbial Natural Products and Biosynthesis
- RNA modifications and cancer
- Plant Stress Responses and Tolerance
- interferon and immune responses
- Plant responses to water stress
- Plant-Microbe Interactions and Immunity
- MicroRNA in disease regulation
- Galectins and Cancer Biology
- Helminth infection and control
- Polysaccharides Composition and Applications
- Carbohydrate Chemistry and Synthesis
- Plant Growth Enhancement Techniques
- Plant Pathogenic Bacteria Studies
- Click Chemistry and Applications
- Circular RNAs in diseases
- Amoebic Infections and Treatments
- Chemical Synthesis and Analysis
- Peroxisome Proliferator-Activated Receptors
- Land Use and Ecosystem Services
- Biochemical and Structural Characterization
- Agriculture, Soil, Plant Science
Jiangxi Academy of Agricultural Sciences
2020-2025
Henan Agricultural University
2014-2024
First Affiliated Hospital of Zhengzhou University
2021-2022
Shandong First Medical University
2022
Jiangsu University
2020-2021
Zhengzhou University
2021
N6 methyladenosine (m6A) modification serves as a novel epigenetic regulatory mechanism that is heavily implicated in the heredity of tumors. Meanwhile, fat mass and obesity-associated protein (FTO) has potential to affect regulation m6A mRNA key oncogenes well tumor suppressor genes facilitate progression. In our study, FTO was downregulated papillary thyroid carcinoma (PTC) tissues. The role PTC assessed by Cell Counting Kit-8 analysis, cell scratch, migration, invasion experiment, flow...
In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden and Egypt were subtyped by multilocus sequence typing (MLST). One to eleven subtypes detected at each the 12 microsatellite, minisatellite single nucleotide polymorphism (SNP) loci, forming 25 MLST subtypes. Host-adaptation significant geographical segregation both observed A clonal population structure was seen C. China Sweden. Three ancestral lineages same RPGR shared these examined....
Abstract Ranthipeptides, defined as radical non‐α thioether‐containing peptides, are a newly emerging class of natural products belonging to the ribosomally synthesized and post‐translationally modified peptide (RiPP) superfamily. Ranthipeptides shown be widespread in bacterial kingdom, whereas heretofore their biological functions remain completely elusive. In this work, putative ranthipeptides investigated from two solventogenic clostridia, Clostridium beijerinckii ljungdahlii , which...
Low temperature (LT) and low illumination (LI) are common meteorological factors posing a great risk to plants. This study aimed clarify quantify the effects of LT, LI, their combined stress (LTLI) on photosynthetic physiological processes strawberry plants during flowering stage. The results indicated that LI increased Chla b levels in while lowering chlorophyll a/b ratio. In contrast, LT LTLI reduced content. All conditions (LT, LTLI) decreased net rate, stomatal conductance, transpiration...
Background. Circular RNA circ_0004771 (termed circNRIP1) was identified by RNA-Seq previously and elevated in papillary thyroid carcinoma (PTC) tissues. A series of studies also showed that circNRIP1 upregulated some tumors could promote the malignant progression tumors. This research intended to focus on role PTC explore mechanisms underlying functions. Methods. RT-PCR or western blot determined circNRIP1, miR-653-5p, pre-B-cell leukemia homeobox 3 (PBX3) expression. EdU, CCK-8, Tunel,...
Waterlogging is a serious abiotic stressor that drastically hinders the growth and productivity of melon (Cucumis melo) around world, due to reduction in available oxygen levels waterlogged tissues. However, mechanism underlying responses waterlogging stress largely unknown. In this study, physiological transcriptome data waterlogging-sensitive accession ‘L39’ waterlogging-tolerant ‘L45’ were investigated under conditions normal water supply stress. The results showed exhibited higher...
Abstract Thyroid Carcinoma (THCA) is the most common endocrine tumor that mainly treated using surgery and radiotherapy. In addition, immunotherapy a recently developed treatment option has played an essential role in management of several types tumors. However, few reports exist on use to treat THCA. The study downloaded miRNA, mRNA lncRNA data for THCA patients from TCGA database ( https://portal.gdc.cancer.gov/ ). Thereafter, samples were divided into cold hot tumors, based immune score...
Osteosarcoma (OS) is a common malignant bone cancer in children and teenagers that originates from osteoblast cells. Although many biomarkers have been reported OS, they not improved the prognosis of this disease. This study sought to identify effective for early diagnosis OS using comprehensive bioinformatics analysis.OS-associated microRNAs (miRNAs) were screened Human microRNA Disease Database (HMDD). The differentially expressed genes (DEGs) related 3 data sets (GSE16088, GSE36001,...
Optimizing rural residential areas (RRAs) in environmentally fragile such as flood detention basins is of great significance for improving the human–land relationship and achieving sustainable development. This study took Xun County central China a case study, established dual minimum cumulative resistance model (DMCR) that considered factors natural attributes policy regulations to evaluate optimization RRAs determined directions strategies accordingly. The main results are: (1) are...
Natural resistance-associated macrophage proteins (NRAMPs) are able to transport various metal ions across cell membranes, which play an important role in plant growth and development. Here, a survey of cucumber (Cucumis sativus L.) watermelon [Citrullus lanatus (Thunb.) Matsum. & Nakai] genomes found total five CsNRAMPs four ClNRAMPs, respectively. Based on the phylogenetic relationships, ClNRAMPs were clustered into three groups (I, II, III). Five orthologous pairs identified between...
Hengshun aromatic vinegar (HSAV), produced by typical solid-state or liquid-state fermentation techniques, is consumed worldwide as a food condiment. HSAV shows multiple bioactivities, but its activity in type 2 diabetes mellitus (T2DM) and possible mechanisms have not been reported. In this study, the effects of against T2DM were evaluated insulin-induced HepG2 cells high-fat diet (HFD) streptozotocin (STZ) induced rats. Then, explored Real-time PCR, Western blot, immunofluorescence assays,...
Abstract Background : Thyroid cancer is the most common endocrine tumor, and papillary thyroid carcinoma common. Commonly used treatment methods include surgery radiotherapy. As an emerging option in recent years, immunotherapy has played essential role of many tumors, but there are few studies cancer. Method We first downloaded mRNA lncRNA data patients from TCGA official website https://portal.gdc.cancer.gov/, miRNA UCSC Xena https://xenabrowser.net/ data. Through tumor microenvironment's...
Abstract BackgroundHashimoto's thyroiditis (HT), also known as chronic lymphocytic thyroiditis, is a common autoimmune disease, which mainly occurs in women. The early manifestation was hyperthyroidism, however, hypothyroidism may occur if HT not controlled for long time. Numerous studies have shown that multiple factors, including genetic, environmental, and were involved the pathogenesis of but exact mechanisms yet clear. aim this study to identify differentially expressed genes (DEGs) by...