A5101485881- Vitamin D Research Studies
- Magnesium in Health and Disease
- Renal Diseases and Glomerulopathies
- Biomedical Research and Pathophysiology
- Autophagy in Disease and Therapy
- Genetic and Kidney Cyst Diseases
- Pancreatic function and diabetes
- Parathyroid Disorders and Treatments
- Biochemical Analysis and Sensing Techniques
Wannan Medical College
2021
First Affiliated Hospital of Wannan Medical College
2021
Southern Illinois University School of Medicine
2008
Abstract The regulation and homeostasis of autophagy are essential for maintaining organ morphology function. As a lysosomal membrane protein, the effect Sidt2 on kidney structure renal is still unknown. In this study, we found that kidneys −/− mice showed changes in basement thickening, foot process fusion, mitochondrial swelling, suggesting was damaged. Increased urine protein at 24 h indicated function also At same time, absence caused decrease number acidic lysosomes, acid hydrolase...
Diabetic nephropathy (DN) is one of the most lethal complications diabetes mellitus with chronic inflammation. We have examined role inflammatory chemokine CCL24 in DN. observed that serum levels were significantly elevated patients Not only that, expression was increased kidneys DN mice. The kidney mice showed renal fibrosis and characterized an vitro podocyte cell model high glucose. Western blot analysis under high-glucose conditions. Stimulation glucose (35 mmol/L) resulted increase...