A5043670511- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Radiation Dose and Imaging
- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Luminescence Properties of Advanced Materials
- Digital Radiography and Breast Imaging
- Prostate Cancer Treatment and Research
- Lung Cancer Treatments and Mutations
- Organic Light-Emitting Diodes Research
- Management of metastatic bone disease
- Radiopharmaceutical Chemistry and Applications
- Organic Electronics and Photovoltaics
- Colorectal Cancer Surgical Treatments
- Radiation Effects in Electronics
- Conducting polymers and applications
- Lung Cancer Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Head and Neck Cancer Studies
- Analytical Chemistry and Sensors
- Intraperitoneal and Appendiceal Malignancies
University of Wollongong
2008-2023
Wollongong Hospital
2017-2022
Illawarra Women's Health Centre
2021
Mount Vernon Hospital
2014-2016
Highland Hospital
1988
To report toxicity and early survival data for IDEAL-CRT, a trial of dose-escalated concurrent chemoradiotherapy (CRT) non-small cell lung cancer.
Abstract During the last 15 years, over 400 patients with adenocarcinoma of rectum have undergone a course endocavitary irradiation for cure or palliation Dukes' A and B disease. This treatment method makes use an unconventional fractionation scheme, by which tumour receives 10000–12000 cGy in approximately four fractions period about 60 days. The treatments are separated interval 2 3 weeks. definitive allows suitable to avoid abdominoperineal resection its drawbacks. Hospitalization is...
Abstract Purpose The PTW microDiamond has an enhanced spatial resolution when operated in edge‐on orientation but is not typically utilized this due to the specifications of IAEA TRS‐483 code practice for small field dosimetry. In work suitability and advantages over recommended face‐on will be presented. Methods both orientations was compared on a Varian TrueBeam linac for: machine output factor (OF), percentage depth dose (PDD), beam profile measurements from 10 × cm 2 0.5 size 6X 6FFF...
When treating prostate cancer using high dose rate (HDR) brachytherapy, overdosing the rectal wall may lead to post-treatment complications. An area of concern is related how calculated by treatment planning systems (TPSs). TPSs are used calculate delivered wall, but they assume that rectum a water-equivalent homogeneous medium infinite size and do not consider effect an air-filled "empty" cavity would have on absorbed along wall. The aim this research quantify air has dose, as its presence...
Four methodologies were evaluated for quantifying kilovoltage cone-beam computed tomography (CBCT) dose: the Cone-Beam Dose Index (CBDI), IAEA Report 5 recommended methodology (IAEA), AAPM Task Group 111 (TG111), and current dose metric; Computed Tomography (CTDI) on two commercial Varian CT imaging systems; Clinac iX On-Board Imager (OBI); TrueBeam X-ray Imaging system (XI). The TG111 measured highest overall (21.199 ± 0.035 mGy OBI 22.420 0.002 XI pelvis imaging) due to full scatter of...
Purpose The development of novel detectors for dosimetry in advanced radiotherapy modalities requires materials that have a water equivalent response to ionizing radiation such characterization beams can be performed without the need complex calibration procedures and correction factors. Organic semiconductors are potentially an ideal technology fabricating devices due tissue equivalence, mechanical flexibility, relatively cheap manufacturing cost. commercial organic photodetector (OPD),...
Measurement of dose delivery is essential to guarantee the safety patients undergoing medical radiation imaging or treatment procedures. This study aimed evaluate ability organic semiconductors, coupled with a plastic scintillator, measure photon in clinically relevant conditions, and establish its hardness. Thereby, proving devices are capable being water-equivalent, mechanically flexible, real-time dosimeter.The shelf-life an photodiode was analyzed 40 kGy by comparison...
Abstract A new printable organic semiconducting material combination as a tissue equivalent photodetector for indirect X‐ray detection is demonstrated in this work. The device exhibits higher optical‐to‐electrical conversion efficiency than any other reported systems photodetection while also operating efficiently with zero applied bias. Complete detectors fabricated by coupling the photodiode plastic scintillator are among first flexible and fully capable of without external response to...
Convolutional neural network (CNN) type artificial intelligences were trained to estimate the Cerenkov radiation present in temporal response of a LINAC irradiated scintillator-fiber optic dosimeter. The CNN is subtracted from combined scintillation and dosimeter, giving sole signal, which proportional scintillator dose. measured dose was compared background subtraction ionisation chamber discrepancy on average 1.4% with respect dose, matching developed CNNs had an time 3 ms calculate...
Purpose The removal of Cherenkov light in an optical dosimetry system is important process to ensure accurate without compromising spatial resolution. Many solutions have been presented the literature, each with advantages and disadvantages. We present a methodology remove from scintillator fiber optic dosimeter pulsed megavoltage x‐ray beam using temporal waveform across pulse. Methods A sample can be measured by exposing only beam. By assuming that closely matches intensity incident...
This study investigated the use of high spatial resolution solid-state detectors (DUO and Octa) combined with an inclinometer for machine-based quality assurance (QA) Volumetric Modulated Arc Therapy (VMAT) flattened flattening filter-free beams.The proposed system was inserted in accessory tray gantry head a Varian 21iX Clinac Truebeam linear accelerator. Mutual dependence dose rate (DR) speed (GS) assessed using standard customer acceptance plan (CAP). The multi-leaf collimator (MLC) leaf...
A large area pixelated silicon array detector named “MP987” has been developed for in vivo dosimetry. The was to overcome the non-water equivalent response of EPID (Electronic Portal Imaging Device) dosimetry systems, due shortfalls extensive corrections required. detector, readout system and software have all custom designed be operated independently from linac with secured directly above EPID, used combination 6 MV imaging system. Dosimetry characterisation measurements percentage depth...
Introduction There is no consensus as to what specifically constitutes head and neck cancer radiotherapy quality assurance (HNC RT QA). The aims of this study are (1) describe the QA processes used in TROG 12.01 study, (2) review undertaken for all patients with loco-regional failure (LRF), (3) provide prospective data propose a statement regarding minimal components optimal timing HNC QA. Materials methods All undergoing original were included substudy. participating sites completed IMRT...
Abstract Introduction: The Pinnacle 3 Auto-Planning (AP) package is an automated inverse planning tool employing a multi-sequence optimisation algorithm. nature of the aims to improve overall quality radiotherapy plans but at same time may produce higher modulation, increasing plan complexity and challenging linear accelerator delivery capability. Methods materials: Thirty patients previously treated with intensity-modulated (IMRT) prostate or without pelvic lymph node irradiation were...
Guidelines for clinical target volume (CTV) to planning (PTV) margins in post-prostatectomy radiation therapy (PPRT) are varied and often not clearly defined. Assessment of appropriateness is commonly measured on prevalence geographic miss.Cone-beam CT (CBCT) images (n = 92) 10 PPRT patients were incorporated provide on-treatment information the six different CTV expansion terms miss change dose-volume statistics CTV, rectum bladder. Uniform included mm, 5 mm + posteriorly 3 posteriorly. In...
Three alternative methodologies to the Computed-Tomography Dose Index for evaluation of Cone-Beam Computed Tomography dose are compared, Index, IAEA Human Health Report No. 5 recommended methodology and AAPM Task Group 111 methodology. The protocols were evaluated Pelvis Thorax scan modes on Varian® On-Board Imager Truebeam kV XI imaging systems. weighted planar average was highest across all scans, with CBDI being second overall. A 17.96% 1.14% decrease from TG-111 protocol mode 18.15%...