A5044874544- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Radiation Detection and Scintillator Technologies
- Radiation Effects in Electronics
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Particle Detector Development and Performance
- Semiconductor materials and devices
- Plasma Diagnostics and Applications
- Calibration and Measurement Techniques
- Integrated Circuits and Semiconductor Failure Analysis
- Optical Systems and Laser Technology
- Ion-surface interactions and analysis
- Prostate Cancer Diagnosis and Treatment
- Nuclear Physics and Applications
- Advanced Optical Sensing Technologies
- Advanced MRI Techniques and Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Boron Compounds in Chemistry
- Semiconductor materials and interfaces
- CCD and CMOS Imaging Sensors
- Radiation Effects and Dosimetry
- Photonic and Optical Devices
- bioluminescence and chemiluminescence research
National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”
2016
Universitair Ziekenhuis Brussel
2015
Institute of Electrodynamics
2009-2013
University of Wollongong
2008
Institute for Single Crystals
2008
National Academy of Sciences of Ukraine
2008
Deutsches Elektronen-Synchrotron DESY
2007
Purpose: Intensity modulated radiation therapy (IMRT) utilizes the technology of multileaf collimators to deliver highly and complex treatment. Dosimetric verification IMRT treatment requires delivered dose distribution. Two dimensional ion chamber or diode arrays are gaining popularity as a dosimeter choice due their real time feedback compared film dosimetry. This paper describes characterization novel 2D array, which has been named “magic plate” (MP). It was designed function transmission...
This work aims to characterize a proton pencil beam scanning (PBS) and passive double scattering (DS) systems as well measure parameters relevant the relative biological effectiveness (RBE) of using silicon on insulator (SOI) microdosimeter with well-defined 3D sensitive volumes (SV). The dose equivalent downstream laterally outside clinical PBS treatment field was assessed compared that DS beam.A novel SVs used in this study. It connected low noise electronics, allowing for detection lineal...
Rectal balloons are used in external beam prostate radiotherapy to provide reproducible anatomy and rectal dose reductions. This is an investigation into the combination of a MOSFET radiation detector with balloon for real-time vivo wall dosimetry. The study that provides water equivalent depth measurement 70 µm. Two MOSFETs were combined face-to-face orientation. reproducibility, sensitivity angular dependence measured dual 6 MV photon beam. was irradiated hypothetical treatments phantom....
Purpose: Silicon diode arrays are commonly implemented in radiation therapy quality assurance applications as they have a number of advantages including: real time operation (compared to the film) and high spatial resolution, large dynamic range small size ionizing chambers). Most detector pitch that is too coarse for routine use field applications. The goal this work characterize two‐dimensional monolithic silicon array named “MagicPlate‐512” (MP512) designed QA stereotactic body (SBRT)...
Microbeam Radiation Therapy (MRT) is a radiation treatment technique under development for inoperable brain tumors. MRT based on the use of synchrotron generated X-ray beam with an extremely high dose rate ( ∼ 20 kGy/sec), striated into array micro-blades. In order to advance clinical trials, real-time dosimeter excellent spatial resolution must be developed absolute dosimetry. The design such scenario represents significant challenge due photon flux and vertically field, leading very steep...
The aim of this study was to measure the microdosimetric distributions a carbon pencil beam scanning (PBS) and passive scattering system as well evaluate relative biological effectiveness (RBE) different ions, namely 12 C, 14 N, 16 O, using silicon-on-insulator (SOI) microdosimeter with well-defined 3D-sensitive volumes (SV). Geant4 simulations were performed same experimental setup results compared for benchmarking.Two silicon microdosimeters rectangular parallelepiped cylindrical shaped...
Microdosimetry is an extremely useful technique, used for dosimetry in unknown mixed radiation fields typical of space and aviation, as well hadron therapy. A new silicon microdosimeter with 3D sensitive volumes has been proposed to overcome the shortcomings conventional Tissue Equivalent Proportional Counter. In this article, charge collection characteristics a mesa were investigated using ANSTO heavy ion microprobe utilizing 5.5 MeV He <sup xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Purpose Nowadays, there are many different applications that use small fields in radiotherapy treatments. The dosimetry of radiation is not trivial due to the problems associated with lateral disequilibrium and source occlusion requires reliable quality assurance ( QA ). Ideally such a tool should provide high spatial resolution, minimal beam perturbation real time fast measurements. Many types silicon diode arrays used for radiotherapy; however, their application filed limited, part, lack...
When treating prostate cancer using high dose rate (HDR) brachytherapy, overdosing the rectal wall may lead to post-treatment complications. An area of concern is related how calculated by treatment planning systems (TPSs). TPSs are used calculate delivered wall, but they assume that rectum a water-equivalent homogeneous medium infinite size and do not consider effect an air-filled "empty" cavity would have on absorbed along wall. The aim this research quantify air has dose, as its presence...
Purpose: Intensity modulated radiation therapy (IMRT) allows the delivery of escalated dose to tumor while sparing adjacent critical organs. In doing so, IMRT plans tend incorporate steep gradients at interfaces between target and organs risk. Current quality assurance (QA) verification tools such as 2D diode arrays, are limited by their spatial resolution conventional films nonreal time. this article, authors describe a novel silicon strip detector (CMRP DMG) high suitable for measuring in...
Purpose Microdosimetry is a vital tool for assessing the microscopic patterns of energy deposition by radiation, which ultimately govern biological effect. Solid‐state, silicon‐on‐insulator microdosimeters offer an approach making microdosimetric measurements with high spatial resolution (on order tens micrometers). These high‐resolution, solid‐state may therefore play useful role in characterizing proton radiotherapy fields, particularly highly resolved within Bragg peak region. In this...
Abstract Purpose The challenges of accurate dosimetry for stereotactic radiotherapy ( SRT ) with small unflattened radiation fields have been widely reported in the literature. In this case, suitable dosimeters would to offer a submillimeter spatial resolution. CyberKnife ® (Accuray Inc., Sunnyvale, CA , USA is an ‐dedicated linear accelerator (linac), which can deliver treatments positional accuracy using circular fields. Beams are delivered desired field size fixed cones, InCise™ multileaf...
Purpose: Stereotactic radiosurgery/therapy (SRS/SRT) is the use of radiation ablation in place conventional surgical excision to remove or create fibrous tissue small target volumes. The SRT/SRS treatment often located close proximity critical organs, hence requirement high geometric precision including a tight margin on planning volume and sharp dose fall off. One major problems with quality assurance (QA) availability suitable detectors required spatial resolution. authors present novel...
Purpose: Spatial and temporal resolutions are two of the most important features for quality assurance instrumentation motion adaptive radiotherapy modalities. The goal this work is to characterize performance 2D high spatial resolution monolithic silicon diode array named "MagicPlate-512" stereotactic body radiation therapy (SBRT) radiosurgery (SRS) combined with a dynamic multileaf collimator (MLC) tracking technique compensation. Methods: MagicPlate-512 used in combination movable...
In this work, the "edgeless" silicon detector technology is investigated, in combination with an innovative packaging solution, to manufacture detectors negligible angular response. The new diode also characterized as a dosimeter for radiotherapy aim verify its suitability single vivo dosimetry well large area 2D array that does not require correction their response.For characterisation of "edgeless-drop-in" technology, set samples have been manufactured different sensitive areas (1 × 1 and...
Due to the ever-increasing complexity of treatment modalities in radiation therapy, there has been a greater need for detectors perform quality assurance ensure patients are treated correctly and safely. Modern therapy techniques involve small field sizes, high dose gradients, varying intensity energy rate. The ideal dosimeter this should display spatial resolution, linearity, accuracy, hardness. Silicon have widely used radiotherapy measurements many attractive qualities as dosimeter;...
The Quality Assurance requirements of detectors for Synchrotron Micro-beam Radiation Therapy are such that there limited commercial systems available. high intensity and spatial fractionation synchrotron microbeams requires be radiation hard capable measuring dose gradients with resolution sensitivity. Silicon single strip a promising candidate applications. PNP detector is an alternative design already proven technology assessed on its contextual viability. In this study, the electrical...
Silicon microdosimeters for the characterisation of mixed radiation fields relevant to space environment have been under continual development at Centre Medical Radiation Physics over a decade. These devices are useful prediction single event upsets in microelectronics and protection spacecraft crew. The latest silicon microdosimetry is family large-area n-SOI real-time dosimetry environments. response 2 MeV H 5.5 He ions has studied investigate their charge collection characteristics....
The responses of two silicon on insulator (SOI) 3-D microdosimeters developed by the Centre for Medical Radiation Physics were investigated with a range different low energy ions, high linear transfer (LET). n-SOI and p-SOI able to measure LET ions including <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">7</sup> Li, xmlns:xlink="http://www.w3.org/1999/xlink">12</sup> C, xmlns:xlink="http://www.w3.org/1999/xlink">16</sup> O,...
This study aims to investigate the 2D monolithic silicon diode array size of 52 × mm2 (MP512) angular response. An correction method has been developed that improves accuracy dose measurement in a small field.The MP512 was placed at center cylindrical phantom, irradiated using 6 MV and 10 photons incrementing incidence beam angle 15° steps from 0° 180°, then 1° between 85° 95°. The response characterized for square field sizes varying 1 cm2 . factor obtained as ratio EBT3 film measured doses...
The metal-oxide-semiconductor field-effect transistor (MOSFET) can be used as a dosimeter. It is robust, lightweight, cost-effective, able to operate in real time with and without external bias, also has very small sensitive volume. Therefore, it particularly suitable for vivo dosimetry modern radiation therapy patient dosimeter diagnostic radiology. MOSFET sensitivity ionizing tailored specific application or dose range. This done by fabricating the radiation-sensitive volume of different...