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Jorge-Antonio Lopez

ORCID: 0000-0003-2109-0001
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About
Contact & Profiles
A5001136144
Research Areas
  • CRISPR and Genetic Engineering
  • DNA Repair Mechanisms
  • RNA modifications and cancer
  • Cancer Genomics and Diagnostics
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • RNA and protein synthesis mechanisms
  • PARP inhibition in cancer therapy
  • Fibroblast Growth Factor Research
  • Bladder and Urothelial Cancer Treatments
  • Epigenetics and DNA Methylation

Roche (Switzerland)
 2021-2022

 Pan-cancer Analysis of Homologous Recombination Repair–associated Gene Alterations and Genome-wide Loss-of-Heterozygosity Score
OPENALEX - Publications 
C. Benedikt Westphalen Alexander D. Fine Fabrice André Shridar Ganesan Volker Heinemann and 6 more Étienne Rouleau Clare Turnbull Luis Garcia Palacios Jorge-Antonio Lopez Ethan Sokol Joaquı́n Mateo

To study associations across tumor types between genome-wide loss of heterozygosity (gLOH) and alterations in homologous recombination repair (HRR)-associated genes beyond BRCA1 BRCA2.

10.1158/1078-0432.ccr-21-2096 article EN cc-by-nc-nd Clinical Cancer Research 2021-11-04
 Pan-tumor landscape of fibroblast growth factor receptor 1-4 genomic alterations
OPENALEX - Publications 
Karthikeyan Murugesan Andrea Necchi Timothy C. Burn Ole Gjoerup R. Greenstein and 9 more Melanie A. Krook Jorge-Antonio Lopez Meagan Montesion Halla Nimeiri A.R. Parikh Sameek Roychowdhury S. Schwemmers Ian M. Silverman Arndt Vogel

10.1016/j.esmoop.2022.100641 article EN cc-by ESMO Open 2022-11-30
 Data from Pan-cancer Analysis of Homologous Recombination Repair–associated Gene Alterations and Genome-wide Loss-of-Heterozygosity Score
OPENALEX - Publications 
C. Benedikt Westphalen Alexander D. Fine Fabrice André Shridar Ganesan Volker Heinemann and 6 more Étienne Rouleau Clare Turnbull Luis Garcia Palacios Jorge-Antonio Lopez Ethan S. Sokol Joaquı́n Mateo

<div>AbstractPurpose:<p>To study associations across tumor types between genome-wide loss of heterozygosity (gLOH) and alterations in homologous recombination repair (HRR)-associated genes beyond <i>BRCA1</i> <i>BRCA2</i>.</p>Experimental Design:<p>Genomic profiling using a targeted next-generation sequencing assay examining 324–465 (FoundationOne, FoundationOne Heme, CDx; Foundation Medicine, Inc.) was performed cohort 160,790 samples...

10.1158/1078-0432.c.6531128 preprint EN 2023-03-31
 Supplementary Data from Pan-cancer Analysis of Homologous Recombination Repair–associated Gene Alterations and Genome-wide Loss-of-Heterozygosity Score
OPENALEX - Publications 
C. Benedikt Westphalen Alexander D. Fine Fabrice André Shridar Ganesan Volker Heinemann and 6 more Étienne Rouleau Clare Turnbull Luis Garcia Palacios Jorge-Antonio Lopez Ethan S. Sokol Joaquı́n Mateo

Supplementary Data from Pan-cancer Analysis of Homologous Recombination Repair–associated Gene Alterations and Genome-wide Loss-of-Heterozygosity Score

10.1158/1078-0432.22483385 preprint EN cc-by 2023-03-31
 Data from Pan-cancer Analysis of Homologous Recombination Repair–associated Gene Alterations and Genome-wide Loss-of-Heterozygosity Score
OPENALEX - Publications 
C. Benedikt Westphalen Alexander D. Fine Fabrice André Shridar Ganesan Volker Heinemann and 6 more Étienne Rouleau Clare Turnbull Luis Garcia Palacios Jorge-Antonio Lopez Ethan S. Sokol Joaquı́n Mateo

<div>AbstractPurpose:<p>To study associations across tumor types between genome-wide loss of heterozygosity (gLOH) and alterations in homologous recombination repair (HRR)-associated genes beyond <i>BRCA1</i> <i>BRCA2</i>.</p>Experimental Design:<p>Genomic profiling using a targeted next-generation sequencing assay examining 324–465 (FoundationOne, FoundationOne Heme, CDx; Foundation Medicine, Inc.) was performed cohort 160,790 samples...

10.1158/1078-0432.c.6531128.v1 preprint EN 2023-03-31
 Supplementary Data from Pan-cancer Analysis of Homologous Recombination Repair–associated Gene Alterations and Genome-wide Loss-of-Heterozygosity Score
OPENALEX - Publications 
C. Benedikt Westphalen Alexander D. Fine Fabrice André Shridar Ganesan Volker Heinemann and 6 more Étienne Rouleau Clare Turnbull Luis Garcia Palacios Jorge-Antonio Lopez Ethan S. Sokol Joaquı́n Mateo

Supplementary Data from Pan-cancer Analysis of Homologous Recombination Repair–associated Gene Alterations and Genome-wide Loss-of-Heterozygosity Score

10.1158/1078-0432.22483385.v1 preprint EN cc-by 2023-03-31
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