A5031740612- Spectroscopy and Quantum Chemical Studies
- DNA and Nucleic Acid Chemistry
- Photochemistry and Electron Transfer Studies
- Advanced biosensing and bioanalysis techniques
- Advanced Fluorescence Microscopy Techniques
- Quantum Information and Cryptography
- DNA Repair Mechanisms
- Photosynthetic Processes and Mechanisms
- Quantum optics and atomic interactions
- Photoreceptor and optogenetics research
- Material Dynamics and Properties
- Mechanical and Optical Resonators
- Bacterial Genetics and Biotechnology
- Spectroscopy and Laser Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Protein Structure and Dynamics
- Mitochondrial Function and Pathology
- RNA Interference and Gene Delivery
- Thermodynamic properties of mixtures
- Porphyrin and Phthalocyanine Chemistry
- RNA and protein synthesis mechanisms
- Nonlinear Optical Materials Studies
- Pickering emulsions and particle stabilization
- Protein Interaction Studies and Fluorescence Analysis
- Electrochemical Analysis and Applications
University of Oregon
2016-2025
Optica
2016-2025
Eugene Research Institute
2019
Institut de Pharmacologie et de Biologie Structurale
2011
Université Toulouse III - Paul Sabatier
2011
Centre National de la Recherche Scientifique
2011
Université de Toulouse
2011
Omega Optics (United States)
2009
University of California, San Diego
1986-2009
Monash University
2007
Two-dimensional electronic coherence spectroscopy (ECS) is an important method to study the coupling between distinct optical modes of a material system. Such studies often involve excitation using sequence phased ultrashort laser pulses. In conventional approaches, delays pulse temporal envelopes must be precisely monitored or maintained. Here, we introduce new experimental scheme for phase-selective nonlinear ECS, which combines acousto-optic phase modulation with produce intensity...
Conventional spectroscopy uses classical light to detect matter properties through the variation of its response with frequencies or time delays.Quantum opens up new avenues for by utilizing parameters quantum state as novel control knobs and photon statistics coupling matter.This Roadmap article focuses on using a powerful sensing spectroscopic tool reveal information about complex molecules that is not accessible light.It aims at bridging optics communities which normally have opposite...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTJaspamide, a modified peptide from Jaspis sponge, with insecticidal and antifungal activityT. Mark. Zabriskie, James A. Klocke, Chris M. Ireland, Andrew H. Marcus, Tadeusz F. Molinski, D. John. Faulkner, Changfu. Xu, Jon. ClardyCite this: J. Am. Chem. Soc. 1986, 108, 11, 3123–3124Publication Date (Print):May 1, 1986Publication History Published online1 May 2002Published inissue 1...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDynamics of ionic lipophilic probes in micelles: picosecond fluorescence depolarization measurementsEdward L. Quitevis, Andrew H. Marcus, and Michael D. FayerCite this: J. Phys. Chem. 1993, 97, 21, 5762–5769Publication Date (Print):May 1, 1993Publication History Published online1 May 2002Published inissue 1 1993https://pubs.acs.org/doi/10.1021/j100123a049https://doi.org/10.1021/j100123a049research-articleACS PublicationsRequest reuse...
We introduce a new method, called entangled photon-pair two-dimensional fluorescence spectroscopy (EPP-2DFS), to sensitively probe the nonlinear electronic response of molecular systems. The method incorporates separated two-photon ('Franson') interferometer, which generates time-frequency-entangled photon pairs, into framework fluorescence-detected 2D optical spectroscopic experiment. photons are temporally shaped and phase-modulated in used excite two-photon-absorbing (TPA) sample, whose...
By applying a phase-modulation fluorescence approach to 2D electronic spectroscopy, we studied the conformation-dependent exciton coupling of porphyrin dimer embedded in phospholipid bilayer membrane. Our measurements specify relative angle and separation between interacting transition dipole moments thus provide detailed characterization conformation. Phase-modulation spectroscopy (PM-2D FS) produces spectra with distinct optical features, similar those obtained using photon-echo...
Two-photon absorption (TPA) and other nonlinear interactions of molecules with time-frequency-entangled photon pairs (EPP) has been predicted to display a variety fascinating effects. Therefore, their potential use in practical quantum-enhanced molecular spectroscopy requires close examination. This paper presents tutorial style detailed theoretical study one- two-photon by molecules, focusing on how treat the quantum nature light. We review some basic optics theory, then we density-matrix...
Entangled photon pairs have been promised to deliver a substantial quantum advantage for two-photon absorption spectroscopy. However, recent work has challenged the previously reported magnitude of enhancement in absorption. Here, we present an experimental comparison sum-frequency generation and molecular absorption, each driven by isolated pairs. We establish upper bound on entangled-two-photon Rhodamine-6G, which lies well below values.
We present a theoretical proof that the “quantum enhancement” of two-photon absorption, thought to be means improve molecular spectroscopy and imaging, is tightly bounded by physics photonic entanglement nonlinear response.
We have used digital video microscopy to study the equilibrium structure of quasi-two-dimensional suspensions sterically stabilized uncharged polymethylmethacrylate spheres. Our experiments reveal existence an hexatic phase as well strongly first-order liquid-to-hexatic and hexatic-to-solid transitions. These observations are in agreement with predictions Bladon Frenkel [Phys. Rev. Lett. 74, 2519 (1995)] for a confined colloid suspension which pair interaction potential between particles has...
We report, from direct observation of particle trajectories as a function time, the presence stringlike cooperative motion in quasi-two-dimensional liquid. have used digital video microscopy to study equilibrium dynamics suspensions sterically stabilized uncharged poly(methylmethacrylate) spheres confined thin glass cell. Our experiments reveal existence, semidilute and dense liquid states, transition qualitative dynamical behavior system. At short times particles undergo unhindered Brownian...
Two-dimensional fluorescence spectroscopy (2D FS) is applied to determine the conformation and femtosecond electronic population transfer in a dimer of magnesium meso tetraphenylporphyrin. The dimers are prepared by self-assembly monomer within amphiphilic regions 1,2-distearoyl-sn-glycero-3-phosphocholine liposomes. A theoretical framework describe 2D FS experiments presented, direct comparison made between observables this measurement those ES). sensitivity method varying explored. global...
DNA "breathing" is a thermally driven process in which base-paired sequences transiently adopt local conformations that depart from their most stable structures. Polymerases and other proteins of genome expression require access to single-stranded coding templates located the double-stranded "interior," it likely fluctuations sugar-phosphate backbones dsDNA result mechanistically useful base pair opening reactions can be exploited by such regulatory proteins. Such motions are difficult...
Compressed sensing is a processing method that significantly reduces the number of measurements needed to accurately resolve signals in many fields science and engineering. We develop two-dimensional variant compressed for multidimensional spectroscopy apply it experimental data. For model system atomic rubidium vapor, we find provides an order-of-magnitude (about 10-fold) improvement spectral resolution along each dimension, as compared conventional discrete Fourier transform, using same...
DNA constructs labeled with cyanine fluorescent dyes are important substrates for single-molecule (sm) studies of the functional activity protein–DNA complexes. We previously studied local backbone fluctuations replication fork and primer–template Cy3/Cy5 donor–acceptor Förster resonance energy transfer (FRET) chromophore pairs showed that, contrary to linked 'externally' bases flexible tethers, direct 'internal' (and rigid) insertion chromophores into sugar-phosphate backbones resulted in...
When a low flux of time-frequency-entangled photon pairs (EPP) illuminates two-photon transition, the rate absorption (TPA) can be enhanced considerably by quantum nature number correlations and frequency correlations. We use quantum-theoretic derivation entangled TPA (ETPA) calculate an upper bound on amount enhancement that is possible in such systems. The derived bounds indicate order to observe ETPA experiments would need operate at combination significantly higher rates EPP...
We have used digital video microscopy to study the equilibrium structure of quasi-two-dimensional suspensions sterically stabilized uncharged polymethylmethacrylate spheres. The spheres are confined between surfaces a very thin glass cell. Our experiments reveal existence an hexatic phase as well strongly first order liquid-to-hexatic and hexatic-to-solid transitions. These observations in agreement with predictions Bladon Frenkel [Phys. Rev. Lett. 74, 2519 (1995)] for colloid suspension...
Studies of wave packet dynamics often involve phase-selective measurements coherent optical signals generated from sequences ultrashort laser pulses. In interferometry (WPI), the separation between temporal envelopes pulses must be precisely monitored or maintained. Here we introduce a new (and easy to implement) experimental scheme for that combines acousto-optic phase modulation with excitation produce an intensity-modulated fluorescence signal. Synchronous detection, respect appropriately...
We have observed the conformation-dependent electronic coupling between monomeric subunits of a dinucleotide 2-aminopurine (2-AP), fluorescent analog nucleic acid base adenine. This was accomplished by extending two-dimensional fluorescence spectroscopy (2D FS) - fluorescence-detected variation 2D to excite molecular transitions in ultraviolet (UV) regime. A collinear sequence four ultrafast laser pulses centered at 323 nm used resonantly coupled 2-AP dinucleotide. The phases optical were...
Understanding the properties of electronically interacting molecular chromophores, which involve internally coupled electronic-vibrational motions, is important to spectroscopy many biologically relevant systems. Here we apply linear absorption, circular dichroism (CD), and two-dimensional fluorescence (2DFS) study polarized collective excitations excitonically cyanine dimers (Cy3)2 that are rigidly positioned within opposing sugar-phosphate backbones double-stranded region a (ss) -...
In this work, we use absorbance, circular dichroism (CD), and two-dimensional fluorescence spectroscopy (2DFS) to study the local conformations conformational disorder within chromophore-labeled DNA constructs.