A5076200101- Gastroesophageal reflux and treatments
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Nanoparticles: synthesis and applications
- Bacterial biofilms and quorum sensing
- Cystic Fibrosis Research Advances
- Gut microbiota and health
- Medicinal Plants and Neuroprotection
- Tracheal and airway disorders
- Pneumonia and Respiratory Infections
- Mycobacterium research and diagnosis
- Influenza Virus Research Studies
- COVID-19 Impact on Reproduction
- Herpesvirus Infections and Treatments
- Helicobacter pylori-related gastroenterology studies
- Dysphagia Assessment and Management
- Viral-associated cancers and disorders
- COVID-19 and Mental Health
- Respiratory and Cough-Related Research
- Cholinesterase and Neurodegenerative Diseases
- Menstrual Health and Disorders
- Clostridium difficile and Clostridium perfringens research
- Acne and Rosacea Treatments and Effects
- Gastrointestinal Bleeding Diagnosis and Treatment
- Alzheimer's disease research and treatments
Hashemite University
2018-2025
Newcastle University
2016-2023
There is a limitation in the range of effectual antibiotics due to Pseudomonas aeruginosa (PA) infection its innate antimicrobial resistance. Researchers have therefore been concentrating their efforts discover advanced and cost effective antibacterial agents among ever-increasing PA bacterial resistance strains. It has discovered that various nanoparticles can be employed as agents. Here, we evaluated properties Zinc Oxide (ZnO NPs), which was biosynthesized, being examined on six hospital...
Abstract The high antibiotic resistance of Pseudomonas aeruginosa (PA) makes it critical to develop alternative antimicrobial agents that are effective and affordable. One the many applications silver nanoparticles (Ag NPs) is their use as an agent against bacteria resistant common antibiotics. key purpose this research was assess antibacterial antibiofilm effectiveness biosynthesized Ag NPs six biofilm-forming clinically isolated strains PA one reference strain (ATCC 27853). were using a...
Background and Objectives: The investigation of oncogenic viruses their potential association with breast cancer (BC) remains an intriguing area study. current work aims to assess evidence three specific viruses, human papillomavirus (HPV), cytomegalovirus (CMV), Epstein–Barr virus (EBV) in BC samples explore relationship relevant clinicopathological variables. Materials Methods: analysis involved from 110 Jordanian female patients diagnosed tissue 30 control no malignancy, investigated...
Abstract Gastro-Oesophageal Reflux (GOR) is a key problem in Cystic Fibrosis (CF), but the relationship between lung and gastric microbiomes not well understood. We hypothesised that CF are related. Gastric sputum cultures were obtained from fifteen patients receiving percutaneous endoscopic gastrostomy feeding. Non-CF juice data was through endoscopy 14 without disease. Bacterial fungal isolates identified by culture. Molecular bacterial profiling used next generation sequencing (NGS) of...
Propionibacterium acnes plays a critical role in the development of acne vulgaris. There has been rise number patients carrying P. strains that are resistant to antibiotics. Thus, alternative anti-microbial agents required. Zinc oxide (ZnO-NPs) and silver (Ag-NPs) nanoparticles can be used against several antibiotic-resistant bacteria. The impact Ag-NPs ZnO-NPs two clinical acnes, P1 P2, reference strain, NCTC747, were investigated this research. A chemical approach for green synthesis from...
Background: Influenza remains a global health challenge, causing significant morbidity and mortality. This study explores the epidemiology of influenza A (IAV) B (IBV) during 2021–2023 winter seasons within targeted Jordanian subpopulation to inform public strategies. Methods: Nasopharyngeal swabs from patients with acute respiratory tract infections (ARTIs) in three major cities were analyzed. RT-PCR was utilized detect common pathogens, specific primers identified IAV (H1N1) pdm09, H3N2,...
Background and objectives: Acute gastroenteritis (AGE) remains a significant cause of morbidity in children, particularly low- middle-income countries. Viral pathogens, including rotavirus (RoV), norovirus (NoV), adenovirus (HAdV), are among the leading causes AGE. This study aimed to determine prevalence viral, bacterial, parasitic enteric pathogens associated with AGE hospitalized children Northern Jordan. Materials Methods: A total 195 stool samples were collected from during winter...
The coronavirus disease 2019 pandemic has been an extraordinarily stressful situation in recent years. Stress is a physiological reaction to negative stimuli that regulated by different neuroendocrine pathways. female reproductive function maintained the menstrual cycle, which negatively affected hyperstimulation of stress signals.This study evaluates effect outbreak on and mental health, exploring relationship between them.The current uses cross-sectional, survey-based design.During this...
Acute respiratory tract infections (ARTIs) during the winter months are associated with higher morbidity and mortality compared to other seasons of year, children below five, elderly, immunocompromised patients being most susceptible. Influenza A B viruses, rhinovirus, coronaviruses, syncytial virus, adenovirus, parainfluenza frequently identified causes viral ARTIs. In addition, emergence SARS-CoV-2 in 2019 provided an additional cause The aim this study was provide overview epidemiological...
This study examines the changes in gastroesophageal reflux disease (GERD) symptom frequency among patients with GERD throughout COVID-19 pandemic.A structured questionnaire was distributed 198 patients. The consisted of a demographic characteristic assessment, GerdQ questionnaire, and index (RSI) questionnaire.A statistically significant increase score identified participants during pandemic (t = 7.055, df 209, p < 0.001), who had experienced an positive predictors decrease negative GERD....
Background There is a need to establish the effectiveness of coronavirus disease 2019 (COVID-19) vaccines in reducing COVID-19-related hopitalization patients Jordan. As vaccination program accelerates, it important determine whether vaccines' (VE) has successfully reduced number acute cases admitted hospital. Methods To efficacy Pfizer-BioNTech and Sinopharm COVID-19 among Jordanian Prince Hamza hospital, single center case-control study was performed. The analyzed hospitalization rates...
Hormesis describes an inverse dose-response relationship, whereby a high dose of toxic compound is inhibitory, and low stimulatory. This study explores the hormetic response concentrations zinc oxide nanoparticles (ZnO NPs) toward Pseudomonas aeruginosa. Samples P. aeruginosa, i.e. reference strain, ATCC 27,853, together with six strains recovered from patients cystic fibrosis, were exposed to ten decreasing ZnO NPs doses (0.78–400 µg/mL). The manufactured Peganum harmala using chemical...
Background and clinical significance: Viral infections are typically considered contributing or secondary factors in the development of breast cancer. Case presentation: This case report presents three instances advanced cancer associated with triple viral infections. 1 involves a 78-year-old woman diagnosed grade 2 invasive ductal carcinoma positive for HPV-18, CMV, BLV. describes 39-year-old carcinoma, HPV-16, 3 is 52-year-old BLV, MMTV. These cases suggest possible correlation between...
This study examined the various manifestations of COVID-19 in people's gastro-intestinal system and how involvement relates to progression outcome disease.A questionnaire survey was used collect data from 561 patients between February 6 April 2022. Laboratory clinical outcomes were obtained patients' medical records.39.9% presented symptoms, mainly loss appetite, nausea, vomiting diarrhea. Gastro-intestinal symptoms not linked poorer such as mortality, ICU admission or length hospital...
Abstract Multi-drug resistant Mycobacterium abscessus complex (MABSC) is a form of Nontuberculous mycobacteria (NTM) special, international concern in Cystic Fibrosis (CF). We hypothesised that gastric juice and percutaneous endoscopic gastrostomy (PEG) feeding devices might yield MABSC isolates. Gastric sputa from sixteen adult PEG fed CF patients five replaced tubes were studied. Bacterial fungal isolates cultured. identified by rpoB, sodA hsp65 gene sequencing strain typed using variable...
The administration of proton pump inhibitors (PPIs) is anticipated to elevate an individual's susceptibility enteric infections as a result altering the gut flora. influence PPIs on clinical manifestation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) still uncertain. This study aims investigate impact PPI usage COVID-19, namely its gastrointestinal symptoms.
Introduction: The most prevalent neurodegenerative illness and kind of dementia is Alzheimer’s disease (AD). It shows up as a reduction in short-term memory cognitive function that affects day-to-day functioning. majority cases are idiopathic, but tiny percentage hereditary instances provide gene identification, which when combined with neuropathology provides crucial hints regarding the broader causes. development course influenced by metabolic environmental risk factors, such vascular...
Given the increasing frequency of drug-resistant bacteria and limited progress in developing new antibiotics, it is necessary to explore methods combating microbial infections. Nanoparticles, particularly silver nanoparticles (Ag-NPs), have shown exceptional antibacterial characteristics; however, elevated concentrations Ag-NPs can produce noticeable levels toxicity mammalian cells.
Human Respiratory Syncytial Virus (HRSV) is a primary cause of severe pediatric respiratory infections, particularly in infants and young children, often resulting hospitalization. The virus possesses high degree mutagenic potential, contributing to significant antigenic diversity, which complicates immune responses poses challenges for vaccine development disease management. This study was conducted Jordan from 2022 2023 epidemiologically determine the prevalence molecular characteristics...
Abstract Studies of microbiota reveal inter-relationships between the microbiomes gut and lungs. This relationship may influence progression lung disease, particularly in patients with cystic fibrosis (CF), who often experience extraoesophageal reflux (EOR). Despite identifying this relationship, it is not well characterised. Our hypothesis that gastric CF are related, potential for aerodigestive pathophysiology. We evaluated sputum bacterial communities by culture 16S rRNA gene sequencing...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung infection has represented a global challenge. Intriguingly, it been shown that the alveolar epithelium expresses little Angiotensin Converting Enzyme receptor protein (ACE2), entry for SARS-CoV-2. Upper airway establishment of and translocation to is well documented but other anatomical niches may be relevant potentially serious infection. ACE2 heavily expressed in gastrointestinal tract symptoms support clinical diagnosis...