A5060281268- Management of metastatic bone disease
- Spine and Intervertebral Disc Pathology
- Advanced Radiotherapy Techniques
- Brain Metastases and Treatment
- Spinal Fractures and Fixation Techniques
- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Colorectal Cancer Screening and Detection
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Surgical Treatments
- Lung Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Treatments and Studies
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Cancer Treatment and Pharmacology
- Prostate Cancer Diagnosis and Treatment
World Health Organization - Pakistan
2024
Tbilisi State Medical University
2019-2024
Abstract Background Patients with metastatic spinal cord compression (MSCC) and favorable survival prognoses can benefit from radiation doses greater than 30Gy in 10 fractions terms of improved local progression-free (LPFS) overall (OS). Methods/design This prospective study mainly investigates LPFS after precision radiotherapy (volumetric modulated arc therapy or stereotactic body radiotherapy) 18 × 2.33Gy 3.5 weeks. is defined as freedom progression motor deficits during an in-field...
Patients with metastatic epidural spinal cord compression (MESCC) and favorable survival prognoses may benefit from radiation doses exceeding 10 x 3.0 Gy. In a multi-center phase 2 trial, patients receiving 15 2.633 Gy (41.6 Gy10) or 18 2.333 (43.2 were evaluated for local progression-free (LPFS), motor/sensory functions, ambulatory status, pain, distress, toxicity, overall (OS). They compared (propensity score adjusted Cox regression) to historical control group (N=266) (32.5 Gy10). the...
Patients with metastatic epidural spinal cord compression (MESCC) and favorable survival prognoses may benefit from radiation doses exceeding 10 × 3.0 Gy. In a multi-center phase 2 trial, patients receiving 15 2.633 Gy (41.6 Gy10) or 18 2.333 (43.2 were evaluated for local progression-free (LPFS), motor/sensory functions, ambulatory status, pain, distress, toxicity, overall (OS). They compared (propensity score-adjusted Cox regression) to historical control group (n = 266) (32.5 Gy10). the...
Introduction: The national burden of gastric cancer (GC) is high in Georgia, which determined by its mortality and low survival. study aimed to estimate the effect age at diagnosis on prognosis GC patients diagnosed between 2015 2020 Georgia. Materials methods: We obtained data for from population-based registry. All 15 years or older, during 2015-2020 with invasive (site codes C16.0 C16.9, International Classification Diseases Oncology), were eligible inclusion analysis. produced survival...
Many patients with malignant spinal cord compression (MSCC) who are not candidates for neurosurgery receive radiotherapy alone. This study compared 15 × 2.633 Gy over three weeks to 20 2.0 four in favorable survival prognoses. The outcomes of 34 treated (equivalent dose 41.6
Estimating post-treatment ambulatory status can improve treatment personalization of patients irradiated for malignant spinal cord compression (MSCC). A new clinical score was developed from data 283 treated with radiotherapy alone in prospective trials. Radiotherapy regimen, age, gender, tumor type, interval diagnosis to MSCC, number affected vertebrae, other bone metastases, visceral time developing motor deficits, status, performance score, sensory and sphincter dysfunction were...
Background/aim: The present study aimed to examine whether the combination of neoadjuvant volumetric modulated arc radiotherapy (VMAT) using simultaneous integrated boost (SIB-VMAT) techniques and chemotherapy with capecitabine is associated better clinical dosimetric outcomes compared standard treatment.Materials methods: included 59 patients cT2?T4 rectal cancer. In arm, (n = 37) were treated preoperatively image-guided VMAT plus capecitabine. SIB 22) SIB-VMAT technique All underwent...
Background Gastric cancer (GC) remains a significant public health issue in many countries globally due to its high morbidity and mortality rates. In Georgia, the incidence of GC reflects prevalence patterns established risk factors. To develop appropriate prevention treatment strategies, requires comprehensive approach research. This study aims review describe epidemiologic characteristics country. Methodology We conducted descriptive analysis utilizing data from national population-based...
Esophageal carcinoma is the seventh most common cancer and sixth lethal worldwide. There are two main histological types of esophageal carcinoma: adenocarcinoma (AC) squamous cell (SCC). Both more in males than females. Menopause an independent risk factor for while usage hormonal therapy (estrogen plus progesterone) associated with a lower SCC postmenopausal women. Gender differences have impact on incidence, however, it unclear if gender has prognostic value survival. The present case...
Locally advanced rectal cancer includes cancers which are extending through the wall and/or regional lymph nodes involved. Preoperative chemoradiotherapy with radiation doses up to 45-50 Gy and radical transabdominal surgery considered as best treatment options in such cases, but dose escalation gross tumor using simultaneous integrated boost technique has been introduced recently. We present a case of locally treated boost, capecitabine surgical intervention.