- COVID-19 epidemiological studies
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and healthcare impacts
- Vaccine Coverage and Hesitancy
- Hepatitis C virus research
- Pneumonia and Respiratory Infections
- Hepatitis B Virus Studies
- Influenza Virus Research Studies
- Mosquito-borne diseases and control
- Respiratory viral infections research
- Liver Disease Diagnosis and Treatment
- COVID-19 and Mental Health
- Healthcare Policy and Management
- Viral Infections and Vectors
- COVID-19 Clinical Research Studies
- Health disparities and outcomes
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Outbreaks Research
- Emergency and Acute Care Studies
- Vector-borne infectious diseases
- Healthcare cost, quality, practices
- Climate Change and Health Impacts
- Global Health Care Issues
- Bacterial Infections and Vaccines
- Long-Term Effects of COVID-19
University Health Network
2009-2025
University of Toronto
2016-2025
Public Health Ontario
2016-2025
Health Net
2018-2025
Institute for Clinical Evaluative Sciences
2015-2024
Toronto Public Health
2015-2024
Toronto General Hospital
2004-2024
Unity Health Toronto
2021-2023
Institute of Health Services and Policy Research
2018-2023
McMaster University
2023
Bloodstream infections (BSIs) represent a substantial mortality risk, yet most studies are limited to select pathogens or populations. The aim of this study was describe the population-wide prevalence BSIs and examine associated risk for responsible microorganisms. We conducted retrospective cohort in Ontario 2017. Blood culture data collected from almost all microbiology laboratories linked sets patient characteristics. For each organism, we determined crude using logistic regression...
To evaluate screening and treatment strategies, large-scale real-world data on liver disease-related outcomes are needed. We sought to validate health administrative for identification of cirrhosis, decompensated cirrhosis hepatocellular carcinoma among patients with known disease.Primary patient were abstracted from the Toronto Center Liver Disease viral hepatitis (2006-2014), all disease Kingston Health Sciences Centre Hepatology Clinic (2013). linked clinical information tested a range...
<h3>BACKGROUND:</h3> The global spread of coronavirus disease 2019 (COVID-19) continues in several jurisdictions, causing substantial strain to health care systems. purpose our study was predict the effect COVID-19 pandemic on patient outcomes and use hospital resources Ontario, Canada. <h3>METHODS:</h3> We developed an individual-level simulation model flow patients with through system Ontario. simulated different combined scenarios epidemic trajectory capacity. Our included number who...
<b>Background:</b> The 2009 influenza A (H1N1) pandemic has required decision-makers to act in the face of substantial uncertainties. Simulation models can be used project effectiveness mitigation strategies, but choice best scenario may change depending on model assumptions and <b>Methods:</b> We developed a simulation outbreak structured population using demographic data from medium-sized city Ontario epidemiologic data. projected attack rate under different combinations vaccination,...
Background: The orthopaedic unit at a university teaching hospital hired an osteoporosis coordinator to identify patients with fragility fracture and coordinate their education, assessment, referral, treatment of underlying osteoporosis. We report the results analysis cost-effectiveness use (in comparison no coordinator) in avoiding future costs subsequent hip fracture. Methods: A one-year decision-analysis model was developed. health outcome fracture; only direct were considered. With...
To design models of the spread coronavirus disease-2019 (COVID-19) in Wuhan and effect Fangcang shelter hospitals (rapidly-built temporary hospitals) on control epidemic.We used data daily reported confirmed cases COVID-19, recovered deaths from official website Municipal Health Commission to build compartmental for three phases COVID-19 epidemic. We incorporated hospital-bed capacity both designated hospitals. assess success strategy adopted epidemic.Based 13 348 beds practice, our show...
Shelter-in-place mandates and closure of nonessential businesses have been central to COVID19 response strategies including in Toronto, Canada. Approximately half the working population Canada are employed occupations that do not allow for remote work suggesting potentially limited impact some proposed mitigate COVID-19 acquisition onward transmission risks associated morbidity mortality. We compared per-capita rates cases deaths from January 23, 2020 24, 2021, across neighborhoods Toronto...
Inequities in the burden of COVID-19 were observed early Canada and around world, suggesting economically marginalized communities faced disproportionate risks. However, there has been limited systematic assessment how heterogeneity risks evolved large urban centers over time.To address this gap, we quantified magnitude risk Toronto, Ontario from January to November 2020 using a retrospective, population-based observational study surveillance data.We generated epidemic curves by social...
Background Type 2 diabetes mellitus (T2DM) and its treatment impact patients’ physical health as well emotional social wellbeing. This study aimed to assess health-related quality of life (HRQoL) associated factors among patients with T2DM at a tertiary care hospital in Ethiopia. Methods A face-to-face cross-sectional survey was conducted Tikur Anbessa Specialized Hospital Addis Ababa, We collected data using validated Amharic version the 5-level EuroQoL-5 dimensions (EQ-5D-5L)...
Introduction The aim of our study was to assess the initial impact COVID-19 on total publicly-funded direct healthcare costs and health services use in two Canadian provinces, Ontario British Columbia (BC). Methods This retrospective repeated cross-sectional used population-based administrative datasets, linked within each province, from January 1, 2018 December 27, 2020. Interrupted time series analysis estimate changes level trends weekly resource costs, with March 16–22, 2020 as first...
In July 2000, the province of Ontario, Canada, initiated a universal influenza immunization program (UIIP) to provide free seasonal vaccines for entire population. This is first large-scale its kind worldwide. The objective this study was conduct an economic appraisal Ontario's UIIP compared targeted (TIIP).A cost-utility analysis using Ontario health administrative data performed. informed by companion ecological comparing physician visits, emergency department hospitalizations, and deaths...
Abstract Background In 2009 and the early part of 2010, northern hemisphere had to cope with first waves new influenza A (H1N1) pandemic. Despite high-profile vaccination campaigns in many countries, delays administration programs were common, high coverage levels not achieved. This experience suggests need explore epidemiological economic effectiveness additional, reactive strategies for combating pandemic influenza. Methods We use a stochastic model investigate realistic that can be used...
Cancer of the cervix is most frequent cancer among women in Ethiopia. The disease burden and its treatment adversely affects patients' health-related quality life (HRQoL). We aimed to investigate HRQoL predictors cervical patients Ethiopia.A hospital-based cross-sectional study was conducted from January June 2018 at oncology unit Tikur Anbessa Specialized Hospital, Addis Ababa, A total 404 were interviewed using validated Amharic version European Organization for Research Treatment module...