A5011239847- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Advanced biosensing and bioanalysis techniques
- Dendrimers and Hyperbranched Polymers
- DNA and Nucleic Acid Chemistry
- RNA Interference and Gene Delivery
- Inorganic Fluorides and Related Compounds
- Advanced Polymer Synthesis and Characterization
- Lanthanide and Transition Metal Complexes
- Crystallography and molecular interactions
- Ionic liquids properties and applications
- Supramolecular Self-Assembly in Materials
- Fluorine in Organic Chemistry
- Luminescence and Fluorescent Materials
Politecnico di Milano
2021-2025
Tuning the self-assembly of dendritic amphiphiles represents a major challenge for design advanced nanomaterials biomimetic applications. The morphology final aggregates, in fact, critically depends on primary structure building blocks as well environmental conditions. Here we report new family fluorinated Janus-type dendrimers (FJDs), based short-chain and branched synthon with 27 magnetically equivalent fluorine atoms, linked to bis-MPA polyester dendrons different generations. Increasing...
Abstract We report halogen‐bonded complexes between 1‐polyfluoroalkyl‐3‐alkylimidazolium iodides and mono‐iodoperfluoroalkanes of different chain lengths or di‐iodoperfluorooctane. 19 F NMR analyses revealed that the preferred stoichiometry donors acceptors is 1 : in cases mono‐iodoperfluoroalkanes, 2 with di‐iodoperfluorooctane, as a result monodentate behavior iodide anion (halogen bond acceptor). Single crystal X‐ray diffraction showed presence perfluorinated superanion, which...
Amphiphiles containing fluorinated segments tend to aggregate in the aqueous solution into structure of lower curvature than their hydrocarbon analogs due larger diameter. A benefit supramolecular structures incorporating fluorine moieties is high electron density, which can be viewed cryo-TEM with better contrast hydrogenated forms. modular approach has been developed for synthesis a new family nonionic branched amphiphiles consisting oligoglycerol units (G2) as hydrophilic part and (F27)...
Nucleic acids, used as therapeutics to silence disease‐related genes, offer significant advantages over small molecule drugs: they provide high specificity, the ability target "undruggable" molecules, and adaptability a wide range of disease phenotypes. However, their instability in biological media, well rapid clearance from organism limit applicability, necessitating use nanocarriers overcome these challenges. Among strategies, spherical nucleic acids (SNA) – composed densely packed corona...
Nucleic acids, used as therapeutics to silence disease‐related genes, offer significant advantages over small molecule drugs: they provide high specificity, the ability target "undruggable" molecules, and adaptability a wide range of disease phenotypes. However, their instability in biological media, well rapid clearance from organism limit applicability, necessitating use nanocarriers overcome these challenges. Among strategies, spherical nucleic acids (SNA) – composed densely packed corona...