A5068454740- Cystic Fibrosis Research Advances
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Pediatric health and respiratory diseases
- Blood Coagulation and Thrombosis Mechanisms
- Atrial Fibrillation Management and Outcomes
- Efficiency Analysis Using DEA
- Healthcare Policy and Management
- Protease and Inhibitor Mechanisms
- ATP Synthase and ATPases Research
- Cardiac and Coronary Surgery Techniques
- Global Health Workforce Issues
- Medication Adherence and Compliance
- Bacterial biofilms and quorum sensing
- Pharmaceutical Economics and Policy
- Oral and gingival health research
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Peptidase Inhibition and Analysis
- Metabolism and Genetic Disorders
- Mitochondrial Function and Pathology
- Biomedical Ethics and Regulation
- Neonatal Respiratory Health Research
- Acute Ischemic Stroke Management
- Health Systems, Economic Evaluations, Quality of Life
Research Triangle Park Foundation
2014-2024
Grifols (United States)
2016-2023
Triangle
2018
Temple Street Children's University Hospital
2016
Michigan Public Health Institute
2002
John Carroll University
2002
Pseudomonas aeruginosa is responsible for chronic infection in many bronchiectasis patients but it not known whether associated with worse clinical outcomes independent of the underlying severity disease. This study analysed data from 2596 included 10 different centres across Europe and Israel, a 5-year follow-up period. Prevalence P. its impact on exacerbations, hospitalisations, quality life mortality was assessed. The prevalence 15.0% (n=389). higher univariate analysis (hazard ratio (HR)...
Non-cystic fibrosis bronchiectasis (NCFBE) is a rare, chronic lung disease characterized by bronchial inflammation and permanent airway dilation. Chronic infections with P. aeruginosa have been linked to higher morbidity mortality. To understand the impact of in NCFBE on health care costs burden, we assessed healthcare utilization before after diagnosis. Using data from 2007 2013 PharMetrics Plus administrative claims, included patients ≥2 claims for >1 claim aeruginosa; then excluded those...
Non-cystic fibrosis bronchiectasis (NCFBE) is a rare, chronic lung disease characterized by bronchial inflammation and permanent airway dilation. Chronic infections with Pseudomonas aeruginosa (PA) have been linked to higher morbidity mortality in NCFBE patients. We assessed healthcare cost utilization the year before after PA diagnosis among US commercially-insured
Introduction: Alpha-1 antitrypsin deficiency (AATD) is often not identified in patients with chronic obstructive pulmonary disease (COPD) until advanced stages of disease, despite the availability genetic testing. While clinical practice guidelines provide recommendations on who should be tested, more refined algorithms are needed to identify COPD likely candidates for AATD testing and prevent delays diagnosis treatment. The objective this study was comorbid associations among diagnosed...
Alpha 1-antitrypsin deficiency (AATD) is a genetic disorder which reduces serum alpha (AAT or alpha1-proteinase inhibitor, A1PI) and increases the risk of chronic obstructive pulmonary disease (COPD). Management strategies include intravenous A1PI augmentation, and, in some cases, health management program (Prolastin Direct®; PD). This study compared clinical economic outcomes between patients with without PD participation. retrospective included commercial Medicare Advantage insurance plan...
Patients with alpha-1 antitrypsin deficiency (AATD) often experience substantial delays from the onset of symptoms to a diagnosis. We explored impact delayed diagnosis AATD on healthcare costs and utilization by assessing costs/utilization before after Retrospective claims data was used conduct longitudinal analysis cohort patients follow-up over four years in commercial database conducted. at least between 2011 – 2017 were included this study. Outcome measures calculated for each year (Year...
<b>Introduction:</b> Chronic infection with Pseudomonas aeruginosa is recognised by bronchiectasis guidelines as a poor prognostic factor and trigger for consideration of prophylactic antibiotic treatment. The prevalence burden P. chronic in BE patients Europe has not been fully defined. <b>Methods:</b> Patients HRCT confirmed aged >18 years from 8 EU affiliated countries were enrolled. CF excluded. followed up to 5 years. Quality life (QoL) was measured using the St Georges Respiratory...
This paper uses health status outputs with Data Envelopment Analysis to assess the relative efficiency of use physician labor inputs. The trends in population growth are examined see if there is a link between ratios and communities they serve. Input scores analyzed for Michigan counties compar-able densities over 10-year period. Overall, approximately 47 percent operated input during decade. In addition assigning an rating, also identifies reference set. set can be used develop composite...
Non-cystic fibrosis bronchiectasis (NCFBE) is a rare, chronic lung disease characterized by bronchial inflammation and permanent airway dilation. Chronic infections with Pseudomonas aeruginosa (PA) have been linked to higher morbidity mortality in NCFBE patients. We assessed treatment patterns for PA among patients US commercially-insured database.
Non-cystic fibrosis bronchiectasis (NCFBE) is a rare, chronic lung disease characterized by bronchial inflammation and permanent airway dilation. Chronic infections with Pseudomonas aeruginosa (PA) have been linked to higher morbidity mortality in NCFBE patients. Prevalence of PA among reported epidemiologic studies be as high 30%, however there has not large nationwide assessment diagnostic patterns the US. This study assessed prevalence diagnosis US commercially insured
Heparin resistance is a common complication of surgical patients requiring anticoagulation, such as those undergoing cardiopulmonary bypass (CPB). Treatments to address heparin include supplementation antithrombin (AT) or fresh frozen plasma (FFP). This retrospective database analysis compared key outcomes in suspected heparin-resistant CPB treated with AT FFP.De-identified United States electronic health records (Cerner Health Facts®) were queried. International Classification Diseases...