This study aimed to purify and partially characterize a keratinolytic protease produced by Bacillus sp. P45 through bioconversion of feather meal. Crude extract was purified using sequence an aqueous two-phase system (ATPS) in large volume systems (10, 50, 500 g) increase obtaining enzyme, followed diafiltration (DF) step. Purified characterized terms protein profile analysis SDS-PAGE, optimum temperature pH, thermal deactivation kinetics at different temperatures performance the presence...

Continuous-flow tubular crystallization in which seed crystals are continuously generated is of interest due to its enabling tighter control crystal properties. This article the most detailed simulation study on design and operation continuous-flow crystallizers using radial mixers, have potential for inducing rapid intense turbulent mixing having easy construction, high reliability, low operating costs. A multiscale model employed that couples computational fluid dynamics (CFD), micromixing...

In this work the fluid dynamics behavior of a draft tube continuous spouted bed with particle bottom feed was studied through experimental data static pressure, fountain height, and mass flow in annulus, as well using computational dynamics. Experiments glass beads solid phase were carried out two different velocity inlet conditions, 20 22 m/s. The rate 0.087 kg/s for first case 0.097 second one. Static pressure measurements done axial radial coordinates entire equipment. height annulus also...

The open-source software, called openCrys, is provided for the multiscale simulation of antisolvent and combined antisolvent-cooling crystallization. It simulates macro- micromixing scales, complete energy population balance equations during crystal nucleation growth. model based on Reynolds-Averaged-Navier–Stokes equation, coupled with a three-environment presumed probability density function model, spatially varying equation semidiscretized using high resolution finite-volume method....

Using a semicylindrical spouted bed to obtain experimental data of cylindrical vessels is an old technique and it has already been widely studied by procedures. In the mathematical modeling beds, specularity coefficient one ways including effect shear stress in solid phase promoted flat wall. This parameter can be included boundary condition represent this friction effect. The main purpose paper discuss numerical influence on fluid dynamics vessel. Several simulations were performed using...

Abstract Glycerol is one of the main byproducts transesterification reaction involved in biodiesel production. Due to its low added value, several efforts have been made make it more economically valuable, including catalytic processes convert into products higher economic benefit, such as acrolein and allyl alcohol. This research work presents synthesis two zeolites with different superficial acid strengths, HZSM-5 NaZSM-5. The performance both materials was evaluated dehydration glycerol...

A cristalização, em muitos processos, é a forma mais comum de produzir compostos químicos alto valor agregado. Na indústria farmacêutica, o método cristalização utilizado consiste na antissolvente, que tem vantagem induzir são facilmente degradados com aumento da temperatura, sem necessitar uma variação brusca mesma. fluidodinâmica computacional (CFD) excelente ferramenta para simular, analisar e projetar sistemas escoamentos complexos, como fenômenos micromistura, ocorrem cristalizadores....

This work investigates how the configuration of geometric parameters a radial crystallizer influences results crystallization lovastatin by antisolvent and using multi-scale computational fluid dynamics (CFD) model. The OPENFOAM open-source software uses macro micromixing expressions for flow, complete energy population equilibrium equations during nucleation crystal growth. model is based on Reynolds-Averaged-Navier-Stokes (RANS) equation, along with multi-environment probability density...

O glicerol é o principal subproduto da produção de biodiesel. A partir desidratação catalítica do possível a obtenção acroleína, qual consiste em um composto utilizado na síntese produtos com alto valor agregado como ácido acrílico. Neste trabalho, zeólita tipo ZSM-5 razão Si/Al 25 foi sintetizada forma sódica (NaZSM-5). catalisador caracterizado por meio das técnicas DRX, MEV e FTIR. Essa convertida para ácida (HZSM-5) troca iônica NH4Cl. As zeólitas nas formas foram aplicadas reação...