Biquan Chen

ORCID: 0000-0003-2171-2122
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About
Contact & Profiles
Research Areas
  • Pneumonia and Respiratory Infections
  • Bacterial Infections and Vaccines
  • Viral-associated cancers and disorders
  • Text and Document Classification Technologies
  • Advanced Computational Techniques and Applications
  • Pediatric Urology and Nephrology Studies
  • Cytomegalovirus and herpesvirus research
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Viral Infections and Immunology Research
  • Parvovirus B19 Infection Studies
  • Kidney Stones and Urolithiasis Treatments
  • Immunodeficiency and Autoimmune Disorders
  • Urinary Tract Infections Management
  • Advanced Image and Video Retrieval Techniques
  • Coronary Artery Anomalies
  • SARS-CoV-2 and COVID-19 Research
  • Viral gastroenteritis research and epidemiology
  • Face recognition and analysis
  • Kawasaki Disease and Coronary Complications
  • S100 Proteins and Annexins
  • Respiratory viral infections research
  • Advanced Nanomaterials in Catalysis
  • Extracellular vesicles in disease
  • Neonatal and Maternal Infections
  • Image Retrieval and Classification Techniques

Anhui Provincial Children's Hospital
2022-2025

Guangxi Academy of Sciences
2024

To analyze the clinical manifestations of children with Kawasaki disease (KD), and risk factors coronary artery lesion (CAL). A total 223 patients admitted to Anhui Children Hospital from January 2017 December 2019 were enrolled. According data, KD divided into complete (CKD) incomplete (IKD) groups. results cardiac color ultrasound, CAL nCAL The symptoms compared between CKD IKD analyzed by univariate binary logistic regression analyses. incidence constituent ratio increased annually (P <...

10.1097/md.0000000000034939 article EN cc-by-nc Medicine 2023-09-15

To analyze the clinical epidemiological characteristics including features, disease prognosis of pneumococcal meningitis (PM), and drug sensitivity S. pneumoniae isolates in Chinese children. A retrospective analysis was performed on clinical, laboratory microbiological data 160 hospitalized children less than 15 years age with PM from January 2019 to December 2020 33 tertiary hospitals China. total patients were diagnosed, 103 males 57 females The onset days old, median 1 year 3 months....

10.3389/fcimb.2024.1353433 article EN cc-by Frontiers in Cellular and Infection Microbiology 2024-03-15

Background: Sepsis is a life-threatening disease caused by infection, and developing novel strategies against sepsis still required. Exosomes derived from mesenchymal stem cells (MSCs) have shown promising therapeutic potential for various diseases. In this study, we aimed to investigate the action mechanism of exosomes IL-1β-pre-conditioned bone marrow-derived stromal (BMSCs) in sepsis. Methods: were isolated BMSCs that pretreated with (IL-1β- BMSC/exos) or without IL-1β (BMSC/exos). vitro,...

10.2174/0115665240277763231206051401 article EN Current Molecular Medicine 2024-01-01

To explore the epidemiological and pathogenic characteristics of children with community-acquired bacterial meningitis.A multicenter, retrospective study was conducted among CABM patients under 15 years old from 33 hospitals in China 2019 to 2020. The medical record, laboratory, microbiological data were collected analyzed.A total 1610 identified presented at a median onset age 45 days whom 955 (59.3%) males. occurred mostly infants <1 year (84.0%, 1352/1610). In etiology-confirmed cases,...

10.2147/idr.s413147 article EN cc-by-nc Infection and Drug Resistance 2023-10-01

Enterovirus 71 (EV71) vaccine for hand-foot-and-mouth disease (HFMD) prevention has been available several years. However, as a new vaccine, the impact of EV71 vaccination on epidemiology and etiology HFMD is currently unclear. The purpose this study was to compare analyze changes epidemiological characteristics patients after introduction vaccine. data hospitalized children with from 2014 2020 were collected case record department tertiary hospital Anhui Province. characteristics, time...

10.1097/md.0000000000030356 article EN cc-by-nc Medicine 2022-09-16

Caroli’s disease is a rare congenital bile duct malformation characterized by intrahepatic dilatation. This kind of situation seldom encountered in clinical work. We report such case who presented to our emergency department with recurrent fever as initial symptom. According the manifestation and imaging examination, 13-year-old boy was diagnosed suppurative cholangitis sepsis caused disease. The symptoms were got relieved after antibiotic therapy upgraded from cephalosporins carbapenems....

10.3389/fped.2022.903285 article EN cc-by Frontiers in Pediatrics 2022-08-04

We attempt to investigate and study the effect of azithromycin combined with budesonide treatment regimen on inflammatory factors therapeutic in patients Mycoplasma pneumonia. 100 pneumonia were selected a hospital from January 2020 December 2022 as investigation subjects divided them into two parts according their admission time, control group consists 50 whose was orally acetyl cysteine nebulization, observation nebulization. Detected serum related index values, clinical efficacy...

10.36468/pharmaceutical-sciences.spl.710 article EN Indian Journal of Pharmaceutical Sciences 2023-01-01
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