- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Escherichia coli research studies
- Vibrio bacteria research studies
- Streptococcal Infections and Treatments
- Infective Endocarditis Diagnosis and Management
- Gut microbiota and health
- Enterobacteriaceae and Cronobacter Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotics Pharmacokinetics and Efficacy
- Clostridium difficile and Clostridium perfringens research
- Neonatal and Maternal Infections
- Mycobacterium research and diagnosis
- Probiotics and Fermented Foods
- Urinary Tract Infections Management
- Antibiotic Use and Resistance
- Tuberculosis Research and Epidemiology
- CRISPR and Genetic Engineering
- Pneumonia and Respiratory Infections
- Oral microbiology and periodontitis research
- Infections and bacterial resistance
- Antimicrobial agents and applications
- Viral gastroenteritis research and epidemiology
Tabriz University of Medical Sciences
2016-2025
Czech Academy of Sciences, Institute of Microbiology
2022
Nuclear Science and Technology Research Institute
2020
Université de Tours
2019-2020
Baku State University
2019-2020
Atomic Energy Organization of Iran
2020
Institute of Immunology
2018-2019
Tarbiat Modares University
2005-2015
Purpose: Many antimicrobial medications are available to combat infections. However, the indiscriminate use of antibiotics has produced antibiotic resistance in case many bacterial pathogens. This study focuses on development nanoparticles (NPs) that enhance vitro activity vancomycin against multi-drug resistant (MDR) organisms. Methods: Spherical shaped thioglycolic acid-stabilized silver (TGA-AgNPs) were prepared by using a simple chemical reduction method. Then, was conjugated terminal...
Abstract Background and objective(s) CRISPR-Cas is a prokaryotic adaptive immune system that protects bacteria archaea against mobile genetic elements (MGEs) such as bacteriophages plasmids, transposons. In this study, we aimed to assess the prevalence of systems their association with antibiotic resistance in one most challenging bacterial pathogens, Klebsiella pneumoniae . Materials methods A total 105 K. isolates were collected from various clinical infections. Extended-spectrum...
The aim of this study was to characterize virulence determinants and antibiotic resistance profiles in enterococci obtained from various clinical sources the northwest Iran. A total 160 enterococcal isolates wards University Teaching Hospitals were collected specified by biochemical test, September 2014 July 2015. Identification confirmed multiplex PCR genus species level. Antibiotic properties examined phenotypic molecular methods. Of isolates, 125 (78.12%) 35 (21.88%) identified as...
The aim of this study was to examine mutations in the quinolone-resistance-determining region (QRDR) gyrA and parC genes Pseudomonas aeruginosa isolates. A total 100 clinical P. isolates were collected from different university-affiliated hospitals Tabriz, Iran. Minimum inhibitory concentrations (MICs) ciprofloxacin levofloxacin evaluated by agar dilution assay. DNA sequences QRDR determined dideoxy chain termination method. Of isolates, 64 resistant ciprofloxacin. No amino acid alterations...
Background: Carbapenem-resistant Enterobacteriaceae (CRE) is a major concern leading to morbidity and mortality in the world. CRE often becoming cause of therapeutic failure both hospital community-acquired infections. Aim: This study aimed investigate resistance mechanisms by phenotypic molecular methods. Materials Methods: Sixty (50 Klebsiella pneumoniae , 6 Escherichia coli 4 Enterobacter spp.) were isolated from October 2018 June 2019. Antimicrobial susceptibility testing was carried out...
Abstract Colorectal cancer (CRC) involves uncontrolled cell growth in the colon and rectum. This study aims to explore prevalence of key pathogenic bacteria their role progression CRC, focusing on microbial dysbiosis. analyzed 52 stool tissue samples through polymerase chain reaction (PCR), real-time PCR, bioinformatics identify associations between CRC progression. PCR results revealed a significant association B.fragilis toxin (bft) gene (P = 0.001, r 0.570). Furthermore, Real-time showed...
Carbapenems have been considered as last line antibiotics for treatment of multidrug-resistant (MDR) Acinetobacter baumannii but carbapenem resistant A. has increased during the decade in many parts world. OXA-type β-lactamase enzymes are most common cause resistance and presence ISAba1 upstream these genes may increase expression OXA genes. The aim this study was to determine, first time, antibiotic pattern prevalence type β-lactamases among nosocomial isolates from northwest Iran. A total...
The purpose of the present study was to investigate diversity genes encoding aminoglycoside-modifying enzymes (AMEs) and their associations with resistance phenotypes clonality in Acinetobacter baumannii Pseudomonas aeruginosa isolates.Seventy six P. 75 A. isolates were collected from three University affiliated hospitals Tehran. MIC determination amikacin gentamicin as well disk diffusion method for tobramycin, netilmicin, kanamycin carried out. Nine AMEs RNA methylases investigated all...
Klebsiella pneumoniae, one of the clinical superbugs, causes diverse infections because its variable capsular antigens. This study focused on K. pneumoniae and aimed to assess any correlation between serotype, capsule-associated virulence genes, evaluate resistance conventional antibiotics in order gain insight into regional differences.A total 61 collected from various specimens were confirmed genotypically. Clinical demographic data for all patients reviewed. All isolates subjected...