A5003398492- Vasculitis and related conditions
- Cerebrovascular and Carotid Artery Diseases
- Hematological disorders and diagnostics
- Sarcoidosis and Beryllium Toxicity Research
- Cardiac Imaging and Diagnostics
- Atherosclerosis and Cardiovascular Diseases
- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Orthopedic Infections and Treatments
- Infectious Diseases and Tuberculosis
- Otitis Media and Relapsing Polychondritis
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Streptococcal Infections and Treatments
- Venous Thromboembolism Diagnosis and Management
- Immune responses and vaccinations
- Diabetes and associated disorders
- Blood properties and coagulation
- Aortic aneurysm repair treatments
- Infective Endocarditis Diagnosis and Management
- Vaccine Coverage and Hesitancy
- Medical Imaging Techniques and Applications
- Orthopaedic implants and arthroplasty
- Systemic Sclerosis and Related Diseases
- Dermatological and COVID-19 studies
University Medical Center Groningen
2020-2021
University of Groningen
2020-2021
Amsterdam University Medical Centers
2020
Amsterdam UMC Location Vrije Universiteit Amsterdam
2012-2017
General Department of Preventive Medicine
2012-2014
ObjectivesTo test whether Bacillus Calmette-Guérin (BCG) vaccination would reduce the incidence of COVID-19 and other respiratory tract infections (RTIs) in older adults with one or more comorbidities.MethodsCommunity-dwelling aged 60 years underlying comorbidities no contraindications to BCG were randomized 1:1 placebo followed for 6 months. The primary endpoint was a self-reported, test-confirmed incidence. Secondary endpoints included hospital admissions clinically relevant RTIs (i.e....
(18)F-FDG-PET visualises inflammation. Both atherosclerosis and giant cell arteritis cause vascular inflammation, but distinguishing the two may be difficult. The goal of this study was to assess interobserver agreement diagnostic accuracy for detection large artery involvement in (GCA).31 (18)F-FDG-PET/CT scans were selected from 2 databases. Four observers assessed wall (18)F-FDG uptake, initially without subsequently with predefined observer criteria (i.e., uptake compared liver or...
Patients with an elevated erythrocyte sedimentation rate (ESR) and non-specific symptoms often pose a diagnostic dilemma. PET/CT visualises infection, inflammation malignancy, all of which may cause ESR. The objective this study was to determine the contribution 18F-fluorodeoxglucose positron emission tomography (PET/CT) in work-up referred patients ESR, whom initial routine evaluation did not reveal diagnosis. We conducted combined retrospective (A) prospective (B) elderly (>50 years)...
Background 18F-FDG-PET(/CT) is increasingly used in studies aiming at quantifying atherosclerotic plaque inflammation. Considerable methodological variability exists. The effect of data acquisition and image analysis parameters on quantitative uptake measures, such as standardized value (SUV) target-to-background ratio (TBR) has not been investigated extensively. Objective goal this study was to explore the several quantification vascular wall 18F-FDG order increase awareness potential...
Abstract. Objectives: Patients with prosthetic joint infections (PJIs) not suitable for curative surgery may benefit from suppressive antibiotic therapy (SAT). However, the usefulness of SAT in cases a draining sinus has never been investigated. Methods: A multicentre, retrospective observational cohort study was performed which patients PJI and tract were eligible inclusion if managed conservatively sufficient follow-up data available (i.e. at least 2 years). defined as period > 6 months...
The benefit of suppressive antibiotic treatment in inoperable patients with a chronic periprosthetic joint infection and sinus tract is unknown. Some physicians prefer to just let the drain, while others treatment. In this viewpoint article we discuss advantages disadvantages particular patient group.
<h3>Background</h3> Patients with rheumatoid arthritis (RA) have an elevated risk of developing cardiovascular disease (CVD). Like active RA, atherosclerosis is inflammatory process. There are indications that aortic inflammation in can be detected on <sup>18</sup>F-Fluorodeoxyglucose-positron emission tomography/computed tomography (<sup>18</sup>F-FDG-PET/CT). <h3>Objectives</h3> To quantify <sup>18</sup>F-FDG uptake large arteries RA patients using PET/CT, as potential reflection vascular...
<h3>Background</h3> Patients with an elevated erythrocyte sedimentation rate (ESR) and non-specific symptoms often pose a diagnostic dilemma. PET/CT visualises infection, inflammation malignancy, all of which may cause ESR. <h3>Objectives</h3> To determine the contribution 18F-fluorodeoxglucose positron emission tomography (PET/CT) in work-up referred patients ESR, whom initial routine evaluation did not reveal diagnosis, order to detect large vessel vasculitis, among other diseases....