A5032307504- Infectious Diseases and Tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Hematological disorders and diagnostics
- Streptococcal Infections and Treatments
- HIV/AIDS Research and Interventions
- Viral-associated cancers and disorders
- Hepatitis C virus research
- Fungal Infections and Studies
- HIV/AIDS drug development and treatment
- Bacterial Infections and Vaccines
- Schizophrenia research and treatment
- Tuberculosis Research and Epidemiology
- Orthopedic Infections and Treatments
- Pleural and Pulmonary Diseases
- Amoebic Infections and Treatments
- Pneumonia and Respiratory Infections
- Liver Disease Diagnosis and Treatment
- Autoimmune Neurological Disorders and Treatments
- Antifungal resistance and susceptibility
- Drug-Induced Adverse Reactions
- Infective Endocarditis Diagnosis and Management
- Psychoanalysis and Psychopathology Research
- Dermatological and Skeletal Disorders
- Esophageal and GI Pathology
- Myasthenia Gravis and Thymoma
Universitat de Miguel Hernández d'Elx
2023-2025
Hospital General Universitario Gregorio Marañón
2024
Hospital Universitari Sant Joan D'Alacant
2009-2024
Organización Nacional de Trasplantes
2023
TIE Kinetix (Germany)
2023
Hospital Universitario 12 De Octubre
2023
Hospital Clínico San Carlos
2017
Centre Hospitalier Universitaire de Nice
2013-2015
Hôpital Pasteur
2012-2015
Hospital Clínico Universitario Lozano Blesa
1999-2015
Background. To report the clinical and epidemiological characteristics of hepatocellular carcinoma (HCC) diagnosed in a cohort human immunodeficiency virus (HIV)–infected patients Spain.
Aim: This study aims to evaluate the utility of fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) test for various infectious indications, analyze its diagnostic value, and assess correlation with suspected diagnoses. Additionally, secondary endpoints include evaluating test's usefulness in clinical management identifying predictors PET/CT positivity. Methods: A retrospective descriptive observational was conducted on in-hospital patients who...
Abstract Background Triple or quadruple drug regimens (3 4DR) remain the gold standard for HIV treatment. However, there is currently a trend towards therapy simplification from 3 4DR to double-drug (2DR) based on Integrase Strand Transfer Inhibitors (INSTIs). Switching 2DR not increased efficacy, as studies suggest non-inferiority of 2DR, but aims reduce adverse events and long-term toxicity associated with prolonged exposure current antiretroviral drugs. date, neither clinical trials nor...
BACKGROUND: Although a priority for tuberculosis control is to achieve the maximum cure rate, compliance with chemotherapy in specific high risk groups (homeless, intravenous drug abusers, chronic alcoholics) usually poor. METHODS: From January 1990 December 1994 102 patients (96 pulmonary, six extrapulmonary) who were poorly compliant treatment treated month fully intermittent (twice weekly) directly observed regimen. They comprised 71 homeless subjects, 50 alcoholics, 23 nine infected HIV,...
To describe the frequency and characteristics of hepatocellular carcinoma (HCC) cases that appeared in HIV/hepatitis C virus (HCV)-coinfected patients with previous sustained virological response (SVR) to compare these those diagnosed without SVR.All HIV/HCV-coinfected HCC 26 hospitals Spain before 31 December 2012 were analyzed. Comparisons between SVR made.One hundred sixty-seven participant hospitals. Sixty-five (39%) them had been previously treated against HCV. In 13 cases, was after...
Determination of plasma cotinine concentration is the predominant assay employed to quantify smoking and exposure environmental tobacco smoke in epidemiological studies. However, biotransformed into secondary metabolites. This pilot study determined concentrations cotinine, glucuronide, 3-hydroxycotinine, 3-hydroxycotinine glucuronide. Total was by summation all four The goals this were (1) explore stability validity total as a measure nonsmokers, (2) each nicotine metabolites smokers...
Medications that act on the central nervous system are frequently used in people infected with human immunodeficiency virus (HIV). Actually, drug interactions an important factor treatment of patients (HIV) infection and because complexity current regimens, clinicians should be trained order to recognize manage interactions. Herein, we present HIV male admitted for manic behavior treated risperidone who developed a profound coma secondary increased levels possible interaction ritonavir...
Darkening of the tongue and oral mucosa is a reaction pattern that can be related to number physiologic, metabolic, toxic disorders, medications exogenous substances. Black discoloration should distinguished from black "hairy" tongue, which characterized by hypertrophy filiform papillae. We report case 42-year-old man presented with his during treatment linezolid for spondylodiscitis. So in conclusion, benign reversible condition probable adverse event associated linezolid. present this...
Recently, there has been an increase in the number of patients with Chagas disease outside areas that are generally considered endemic. The aim this investigation is to describe clinical profile a series Alicante, Spain, which province located on coast Mediterranean Sea. This study was performed at four general hospitals Alicante between January 2002 and May 2011. A total 128 from seven countries were diagnosed Trypanosoma cruzi. main country origin these Bolivia (n5101; 78.9%), median age...
Background: Although the pathogenic role of Coxiella burnetii infection during pregnancy is controversial, some cases stillbirth and abortion occurring after an acute or chronic have been mentioned in literature. Recently, Q fever has advocated as a significant cause morbidity mortality Case: We describe 18‐year‐old primipara woman admitted to our hospital for high pancytopenia C. infection. She was successfully treated with clarithromycin, overcoming pancytopenia. Finally, she gave birth...
To report a case of persistent hiccups associated by azithromycin therapy.A 76-year-old man presented with after beginning for the treatment pharyngitis. Hiccups were and exhausting. Discontinuation therapy baclofen finally resolved hiccups. No organic cause was identified despite extensive investigation.Pharmacotherapeutic agents have been uncommonly Corticosteroids (dexamethasone methylprednisolone), benzodiazepines (midazolam) general anaesthesia specific mentioned most frequently in...
Abstract. Objectives: Patients with prosthetic joint infections (PJIs) not suitable for curative surgery may benefit from suppressive antibiotic therapy (SAT). However, the usefulness of SAT in cases a draining sinus has never been investigated. Methods: A multicentre, retrospective observational cohort study was performed which patients PJI and tract were eligible inclusion if managed conservatively sufficient follow-up data available (i.e. at least 2 years). defined as period > 6 months...
Empyema necessitatis is a collection of inflammatory tissue that ruptures spontaneously through weakness in the chest wail into surrounding soft tissues. Although empyema can be caused by number infectious agents, mycobacteria are most frequently implicated. was much more common complication pulmonary tuberculosis preantibiotic era than it today. We describe 22-year-old man with human immunodeficiency virus (HIV) infection who had tuberculous and successfully treated surgical debridement...
Switching therapy studies are usually designed as second-line antiretroviral treatment (ART) in patients without previous virologic failures. Combined ART (cART) with DRV/r and ETR has a good pharmacokinetic profile, high genetic barrier been proved rescue therapy. The aim of our study was to analyze efficacy safety plus experienced HIV-patients therapeutic failures that need switch ART. We present results at first 24 weeks.Multicentre retrospective observational study.adult on HIV-VL <1000...
Myeloradiculitis is a rare neurological complication of herpes simplex type 2 (HSV-2) infection, frequently associated with fatal outcome. Among patients HIV HSV-2 myeloradiculitis has occasionally been reported, always advanced immunosuppression and AIDS. We report patient infection but no history previous opportunistic infections, who developed sacral immediately after an episode genital herpes. Magnetic resonance imaging gadolinium showed necrotizing myelitis in the conus medullaris...