A5046769956- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Hepatitis C virus research
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis B Virus Studies
- Antibiotic Use and Resistance
- HIV/AIDS drug development and treatment
- SARS-CoV-2 and COVID-19 Research
- Liver Disease Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- HIV Research and Treatment
- HIV-related health complications and treatments
- Emergency and Acute Care Studies
- HIV/AIDS oral health manifestations
- Antifungal resistance and susceptibility
- SARS-CoV-2 detection and testing
- Antimicrobial Resistance in Staphylococcus
- Hospital Admissions and Outcomes
- COVID-19 epidemiological studies
- Venous Thromboembolism Diagnosis and Management
- Pneumonia and Respiratory Infections
- Streptococcal Infections and Treatments
- Frailty in Older Adults
- Respiratory viral infections research
- Healthcare Policy and Management
Hospital Universitario Fundación Alcorcón
2016-2025
Hospital General Universitario Gregorio Marañón
2021-2024
Universidad Rey Juan Carlos
2011-2023
Hospital Universitari i Politècnic La Fe
2022
Hospital Clínic de Barcelona
2022
Universitat de Barcelona
2022
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2022
Hospital Universitario Ramón y Cajal
2022
Universidad de Navarra
2022
Hospital Clínico San Carlos
2021-2022
In patients with Candida parapsilosis candidemia, the use of an echinocandin-based regimen for first 72 hours therapy had no impact on odds clinical failure, despite lower in vitro activity this class antifungals.
Abstract Evidence shows that engaging in sexualized drug use (SDU) can be associated with sexual health problems and poor mental health. However, the prevalence of drug-related SDU remains unclear. Our study aimed to examine factors dependence a sample gay, bisexual, other men who have sex living HIV (HIV + GBMSM). We included 101 GBMSM had engaged last year. Participants completed an online survey featuring validated questionnaire (the DUDIT test) assess risk dependence. Univariate...
We evaluated treatment outcomes in a prospective registry of human immunodeficiency virus/hepatitis C virus (HCV)–coinfected patients treated with interferon‐free direct‐acting antiviral agent–based therapy hospitals from the region Madrid between November 2014 and August 2016. assessed sustained viral response at 12 weeks after completion used multivariable logistic regression to identify predictors failure. 2,369 patients, whom 59.5% did not have cirrhosis, 33.9% had compensated 6.6%...
The high transmissibility of SARS-CoV-2 before and shortly after the onset symptoms suggests that only diagnosing isolating symptomatic patients may not be sufficient to interrupt spread infection; therefore, public health measures such as personal distancing are also necessary. Additionally, it will important detect newly infected individuals who remain asymptomatic, which account for 50% or more cases. Molecular techniques “gold standard” diagnosis infection. However, massive use these has...
The present study aimed to assess the association of obesity and malnutrition with mortality hospitalised patients acute exacerbation chronic obstructive pulmonary disease (COPD) risk readmission in <30 days.A retrospective chart review consecutive admitted COPD as primary reason for discharge Spain between 1 January 2006 31 December 2007 was performed. Patients a diagnosis or hospital clinical report were identified. in-hospital re-admittance 30 days after indices obese malnourished...
ObjectiveParadoxical growth (PG) and trailing effect (TE) are frequently observed during antifungal susceptibility testing (AFST). These two phenomena interfere with the determination of minimal inhibitory concentration (MIC). The aim this study was to assess clinical impact TE PG.MethodsWe analysed frequency PG 690 Candida isolates collected from a population-based performed in Spain (CANDIPOP) correlated results outcome patients.ResultsAround 70% (484/690) exhibited azoles. tropicalis...
We analysed hepatitis C virus (HCV) reinfection among participants in a prospective registry of HIV/HCV-coinfected patients treated with all-oral direct-acting antiretroviral (DAA)-based therapy the region Madrid.An observational cohort study.The study period started on date sustained viral response (SVR) was confirmed. The censoring 31 December 2017. SVR defined as negative HCV-RNA 12 weeks after completion treatment. Reinfection positive test result achievement SVR.Reinfections were...
The management of patients admitted during weekends may be compromised because the level staffing in hospital is often lower then. This study was conducted to assess what independent influence, if any, weekend admission might have on inhospital mortality. authors analyzed clinical data 429,880 adults >14 years age who were internal medicine wards Spain after having presented hospitals' emergency departments. Overall mortality and early (occurring first 48 hours) examined, taking into account...
Aging societies worldwide propose a significant challenge to the model and organisation of delivery healthcare services. In developing countries, communicable non-communicable diseases are affecting how ageing population access healthcare; this could be due varying reasons such as geographical barriers, limited financial support poor literacy. New information communication technology, eHealth have potential improve healthcare, exchange improving public personalised medicine for elderly...
micro-elimination has been recently proposed as an efficient strategy to achieve global hepatitis C virus (HCV) elimination. The Spanish Health Ministry Strategic Plan for infection highlighted intervention in prisons a priority action. However, there are important barriers associated with the specialized care provision penitentiary population.to assess contribution of telemedicine HCV elimination correctional facility Spain.an open label program via was started on February 3rd, 2015 large...
ABSTRACT Background Health-care workers (HCW) are at increased risk for SARS-CoV-2 infection, but few studies have evaluated prevalence of antibodies against among them. Objective To determine the seroprevalence in all HCW. Methods Cross-sectional study (April 14 th - 27 , 2020) HCW Hospital Universitario Fundación Alcorcón, a second level teaching hospital Madrid, Spain. IgG was measured by ELISA. were classified professional category, working area, and exposure. Results Among 2919 HCW,...
Abstract Objectives We assessed the prevalence of anti‐hepatitis C virus (HCV) antibodies and active HCV infection (HCV‐RNA‐positive) in people living with HIV (PLWH) Spain 2019 compared results those four similar studies performed during 2015–2018. Methods The study was 41 centres. Sample size estimated for an accuracy 1%. Patients were selected by random sampling proportional allocation. Results reference population comprised 973 PLWH, sample 1325. serostatus known 1316 PLWH (99.3%), whom...
The prevalence of comorbid anemia in patients with COPD ranges from 7.5% to 34%. aim this study is determine if a risk factor for readmission patients.This analyzed the hospital data 289,077 adults acute exacerbations admitted at any public center Spain, 2006 and 2007. We calculated compared readmissions between without anemia. Multiple regression analyses were carried out determining attributable anemia, after correction possible confounding variables.Of COPD, 9.8% (n = 26,899) had...
The purpose of this study was to determine among patients with candidemia the real rate ophthalmoscopy and impact performing ocular assessment on outcome disease. We performed a post hoc analysis prospective, multicenter, population-based surveillance program implemented in Spain during 2010–2011 (CANDIPOP). Ophthalmoscopy only 168 365 (46%). Ocular lesions related were found 13/168 (7.7%), whom 1 reported symptoms (incidence symptomatic disease whole population, 0.27% [1/365])....