A5034608679- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Plant Pathogens and Fungal Diseases
- Nail Diseases and Treatments
- Infectious Diseases and Mycology
- Antibiotics Pharmacokinetics and Efficacy
- Antimicrobial Resistance in Staphylococcus
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Neutropenia and Cancer Infections
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Mycotoxins in Agriculture and Food
- Nosocomial Infections in ICU
- Fungal Biology and Applications
- Advanced biosensing and bioanalysis techniques
- Antibiotic Resistance in Bacteria
- Probiotics and Fermented Foods
- Cystic Fibrosis Research Advances
- Oral microbiology and periodontitis research
- Bacterial biofilms and quorum sensing
- Helminth infection and control
- Pharmaceutical studies and practices
- Insects and Parasite Interactions
- SARS-CoV-2 detection and testing
Hospital Universitari i Politècnic La Fe
2016-2025
Instituto de Investigación Sanitaria La Fe
2013-2024
Leitat Technological Center
2017-2024
Hospital General Universitario Gregorio Marañón
2013-2024
Organización Nacional de Trasplantes
2023
TIE Kinetix (Germany)
2023
Hospital Universitario 12 De Octubre
2023
Hospital Clínic de Barcelona
2022
Universitat de Barcelona
2022
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2022
Summary Multidrug‐resistant Candida auris has emerged as a cause of insidious hospital outbreaks and complicated infections. We present the analysis an ongoing C. outbreak including largest published series bloodstream infection. All auris‐ positive patients from April‐2016 to January‐2017 were included. Environmental, clinical microbiological data recorded. Definitive isolate identification was performed by ITS ‐ rDNA sequencing, typing amplified fragment length polymorphism fingerprinting....
A population-based survey was conducted to investigate the epidemiology of and antifungal resistance in Spanish clinical strains filamentous fungi isolated from deep tissue samples, blood cultures, respiratory samples. The study two different periods (October 2010 May 2011) analyze seasonal variations. total 325 were 29 hospitals. average prevalence 0.016/1,000 inhabitants [corrected]. Strains identified by sequencing DNA targets susceptibility testing European Committee for Antimicrobial...
Clinical breakpoints (CBPs) and epidemiological cutoff values (ECVs) have been established for several Candida spp. the newer triazoles echinocandins but are not yet available older antifungal agents, such as amphotericin B, flucytosine, or itraconazole. We determined species-specific ECVs B (AMB), flucytosine (FC) itraconazole (ITR) eight (30,221 strains) using isolates from 16 different laboratories in Brazil, Canada, Europe, United States, all tested by CLSI reference microdilution...
To update the knowledge of epidemiology fungaemia episodes in Spain, species implicated and their vitro antifungal susceptibilities. Episodes were identified prospectively over 13 months at 44 hospitals. Molecular methods used to determine cryptic inside Candida parapsilosis glabrata complexes. Susceptibility amphotericin B, anidulafungin, caspofungin, fluconazole, flucytosine, itraconazole, micafungin, posaconazole voriconazole was determined by a microdilution colorimetric method. New...
A 13-month prospective multicenter study including 44 hospitals was carried out to evaluate the epidemiology of Candida parapsilosis complex candidemia in Spain. Susceptibility amphotericin B, flucytosine, fluconazole, itraconazole, voriconazole, posaconazole, anidulafungin, caspofungin, and micafungin tested by microdilution colorimetric method. total 364 C. isolates were identified molecular methods: (90.7%), orthopsilosis (8.2%), metapsilosis (1.1%). Most candidemias (C. parapsilosis,...
To determine the epidemiology of Candida bloodstream infections, variables influencing mortality, and antifungal resistance rates in ICUs Spain.Prospective, observational, multicenter population-based study.Medical surgical 29 hospitals distributed throughout five metropolitan areas Spain.Adult patients (≥ 18 yr) with an episode infection during admission to any surveillance area ICU from May 2010 April 2011.Candida isolates were sent a reference laboratory for species identification by DNA...
ABSTRACT We report the molecular identifications and antifungal susceptibilities of isolates causing fungemia collected in CANDIPOP population-based study conducted 29 Spanish hospitals. A total 781 (from 767 patients, 14 them having mixed fungemia) were collected. The species found most frequently Candida albicans (44.6%), parapsilosis (24.5%), glabrata (13.2%), tropicalis (7.6%), krusei (1.9%), guilliermondii (1.7%), lusitaniae (1.3%). Other non- accounted for approximately 5% isolates....
In patients with Candida parapsilosis candidemia, the use of an echinocandin-based regimen for first 72 hours therapy had no impact on odds clinical failure, despite lower in vitro activity this class antifungals.
Seventeen laboratories participated in a study of interlaboratory reproducibility with caspofungin microdilution susceptibility testing against panels comprising 30 isolates Candida spp. and 20 Aspergillus The used materials supplied from single source to determine the influence growth medium (RPMI 1640 or without glucose additions antibiotic 3 [AM3]), same incubation times (24 h 48 h), end point definition (partial complete inhibition growth) for MIC caspofungin. All tests were run...
Twenty-six cases of Blastoschizomyces capitatus infection were diagnosed in 25 patients at 7 tertiary care hematology units Spain over a 10-year period. Most (92%) had acute leukemia and developed during period severe prolonged neutropenia. Two esophagitis, the rest invasive infection. Fungemia (20 cases) was common finding, with frequent visceral dissemination. The 30-day mortality associated this 52%, compared 57% among systemic In univariate analysis, following 3 variables positive impact...