José Antonio Serra Rexach

ORCID: 0000-0003-1698-0624
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About
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Research Areas
  • Frailty in Older Adults
  • Nutrition and Health in Aging
  • Hip and Femur Fractures
  • Cardiac, Anesthesia and Surgical Outcomes
  • Health Systems, Economic Evaluations, Quality of Life
  • Intensive Care Unit Cognitive Disorders
  • Aging, Health, and Disability
  • Body Composition Measurement Techniques
  • Geriatric Care and Nursing Homes
  • Physical Activity and Health
  • Chronic Disease Management Strategies
  • Cardiac Health and Mental Health
  • Pelvic and Acetabular Injuries
  • Emergency and Acute Care Studies
  • Bone health and osteoporosis research
  • Infectious Diseases and Tuberculosis
  • Cardiovascular and exercise physiology
  • Balance, Gait, and Falls Prevention
  • Nursing care and research
  • Dementia and Cognitive Impairment Research
  • Tracheal and airway disorders
  • Dysphagia Assessment and Management
  • Heart Failure Treatment and Management
  • COVID-19 Clinical Research Studies
  • HIV-related health complications and treatments

Pontificia Universidad Católica de Chile
2025

Hospital General Universitario Gregorio Marañón
2015-2024

Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable
2017-2024

Universidad Complutense de Madrid
2012-2024

Instituto de Salud Carlos III
2019-2024

Centro de Investigación Biomédica en Red
2017-2021

Madrid Health Service
2011-2014

Universidad Europea
2011

Karolinska Institutet
2011

Universidad de Granada
2011

Objectives: To evaluate whether an early multidisciplinary geriatric intervention in elderly patients with hip fracture reduced length of stay, morbidity, and mortality improved functional evolution. Design: Randomized, controlled trial. Setting: Orthopedic ward a university hospital. Participants: Three hundred nineteen aged 65 older hospitalized for surgery. Intervention: Participants were randomly assigned to daily (n=155) or usual care (n=164) during hospitalization the acute phase...

10.1111/j.1532-5415.2005.53466.x article EN Journal of the American Geriatrics Society 2005-09-01

<b><i>Objective:</i></b> To evaluate the efficacy of a cognitive-motor program in patients with early Alzheimer disease (AD) who are treated cholinesterase inhibitor (ChEI). <b><i>Methods:</i></b> Patients mild cognitive impairment (MCI) (12), AD (48), and moderate (24) (Global Deterioration Scale stages 3, 4, 5) were randomized to receive psychosocial support plus intervention (experimental group) or alone (control group). Cognitive-motor (CMI) consisted 1-year structured 103 sessions...

10.1212/01.wnl.0000147478.03911.28 article EN Neurology 2004-12-28

The clinical effect of surgical delay in older patients with hip fracture is controversial. Discrepancies among study findings may be due to confounding that caused by the reason for or a differential on patient risk subgroups.To assess hospital outcomes according cause delay.Prospective cohort study.A unit university Spain.2250 consecutive elderly fracture.Time surgery, reasons delay, adjusted in-hospital death, and complications.Median time surgery was 72 hours. Lack operating room...

10.7326/0003-4819-155-4-201108160-00006 article EN Annals of Internal Medicine 2011-08-16

OBJECTIVES: To analyze the effectiveness of a multicomponent intervention integrated into daily practice for prevention in‐hospital delirium in elderly patients. DESIGN: Controlled study comparing an geriatric unit (GI) with usual care two internal medicine services (UC). SETTING: University hospital Madrid, Spain. PARTICIPANTS: Five hundred forty‐two consecutive patients (170 GI, 372 UC), aged 70 and older, any risk criteria (cognitive impairment, visual acute disease severity,...

10.1111/j.1532-5415.2009.02485.x article EN Journal of the American Geriatrics Society 2009-09-15

To assess the effects of an 8-week exercise training program with a special focus on light- to moderate-intensity resistance exercises (30-70% one repetition maximum, 1RM) and subsequent 4-week cessation period (detraining) muscle strength functional capacity in participants aged 90 older.Randomized controlled trial performed during March September 2009.Geriatric nursing home.Forty nonagenarians (90-97) were randomly assigned intervention or control group (16 women 4 men per...

10.1111/j.1532-5415.2011.03356.x article EN Journal of the American Geriatrics Society 2011-03-31

Societies are progressively aging, with the oldest old (i.e., those aged >80–85 years) being most rapidly expanding population segment. However, advanced aging comes at a price, as it is associated an increased incidence of so-called age-related conditions, including greater risk for loss functional independence. How to combat sarcopenia, frailty, and overall intrinsic capacity decline in elderly major challenge modern medicine, exercise appears be potential solution. In this article, we...

10.1002/cphy.c190002 article EN Comprehensive physiology 2019-09-19

To assess the prevalence of major geriatric syndromes (MGSs)-frailty, cognitive impairment, severe dependence and depression-and their influence on outcomes in unselected patients with acute cardiac diseases.Observational prospective study 12-month clinical functional follow-up.Clinical cardiology unit a university hospital Madrid, Spain.Consecutive ≥75 years old urgently admitted to unit.Systematic comprehensive assessment.12-month rates mortality, readmission, decline need for new social...

10.1136/hrt.2011.227504 article EN Heart 2011-07-27

The clinical scenario of heart failure (HF) in older hospitalized patients is complex and influenced by acute chronic comorbidities, coexistent geriatric syndromes, the patient's ability for self-care after discharge, degree social support. impact all these factors on outcomes or disability evolution not sufficiently known. FRAIL-HF a prospective observational cohort study designed to evaluate (mortality readmission), functional evolution, quality life, use resources at 1, 3, 6, 12 months...

10.1002/clc.22345 article EN Clinical Cardiology 2014-12-01

The high transmissibility of SARS-CoV-2 before and shortly after the onset symptoms suggests that only diagnosing isolating symptomatic patients may not be sufficient to interrupt spread infection; therefore, public health measures such as personal distancing are also necessary. Additionally, it will important detect newly infected individuals who remain asymptomatic, which account for 50% or more cases. Molecular techniques “gold standard” diagnosis infection. However, massive use these has...

10.37201/req/120.2020 article EN cc-by-nc Revista Española de Quimioterapia 2020-10-19

The aging of our societies leads to a higher prevalence multimorbidity and therefore polypharmacy, which often results in inappropriate drug treatment. To address this issue, numerous listing approaches, such as the Fit fOR Aged (FORTA) list have been developed. FORTA's positive impact on quality medications relevant clinical outcomes has shown. Based new emerging evidence experiences with existing FORTA lists, we aimed update lists several European countries/regions.Two-step Delphi...

10.1007/s40266-023-01024-6 article EN cc-by-nc Drugs & Aging 2023-05-01

INTRODUCCIÓNLa fractura de la extremidad proximal del fémur o cadera (FC) es complicación más importante osteoporosis en términos mortalidad, morbilidad y costes (1).Puede producirse a cualquier edad pero aproximadamente el 90% los casos ocurren personas 64 años (2) teniendo cuenta las tendencias demográficas prever un aumento número fracturas próximos (3).Existen multitud trabajos que analizan incidencia FC tanto España (4-8) como resto Europa (9-11), Estados Unidos América (12), Asia...

10.4321/s0212-71992002000800002 article ES Anales de Medicina Interna 2002-08-01

Abstract Learning Objectives After completing this course, the reader will be able to: Use patient age as only one consideration, along with tumor status and comorbidities, in deciding on treatment strategies for elderly colorectal cancer patients.Obtain apply information regarding medical, functional, mental, social of patients order to make appropriate therapeutic decisions. CME This article is available continuing medical education credit at CME.TheOncologist.com Purpose. To analyze...

10.1634/theoncologist.2012-0060 article EN The Oncologist 2012-08-23

Falling is a major clinical problem in elderly people, demanding effective solutions. At present, the only intervention motor training of balance and strength. Executive function-based (EFt) might be at preventing falls according to evidence showing relationship between executive functions gait abnormalities. The aim was assess effectiveness cognitive treatment developed within EU co-funded project I-DONT-FALL.In sample 481 people risk recruited this multicenter randomised controlled trial,...

10.3390/brainsci7020019 article EN cc-by Brain Sciences 2017-02-10

Background.The main objective of this study was to analyze the independent effect increasing age on recovery different areas functioning 1 year after hip fracture.

10.1093/gerona/glr231 article EN The Journals of Gerontology Series A 2012-01-04
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