A5101490218- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Frailty in Older Adults
- SARS-CoV-2 detection and testing
- COVID-19 and healthcare impacts
- Hip and Femur Fractures
- Nutrition and Health in Aging
- Helicobacter pylori-related gastroenterology studies
- Acute Myocardial Infarction Research
- Lymphoma Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Renal Transplantation Outcomes and Treatments
- Cardiac electrophysiology and arrhythmias
- Chronic Lymphocytic Leukemia Research
- Dialysis and Renal Disease Management
- Childhood Cancer Survivors' Quality of Life
- Eosinophilic Esophagitis
- Heart Failure Treatment and Management
- Global Cancer Incidence and Screening
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare cost, quality, practices
- Organ Transplantation Techniques and Outcomes
- Transplantation: Methods and Outcomes
- Long-Term Effects of COVID-19
- Pharmaceutical Practices and Patient Outcomes
Hospital Universitario de La Princesa
1989-2025
University of O'Higgins
2024
Pontificia Universidad Católica de Chile
2021-2022
Hospital General Universitario Gregorio Marañón
2007-2021
Universidad de Colima
2021
Hospital Clínico de la Universidad de Chile
2021
Universidad Autónoma de Madrid
2019
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2019
Biomechanics Institute of Valencia
2016
Madrid Health Service
2014
Objectives: To evaluate whether an early multidisciplinary geriatric intervention in elderly patients with hip fracture reduced length of stay, morbidity, and mortality improved functional evolution. Design: Randomized, controlled trial. Setting: Orthopedic ward a university hospital. Participants: Three hundred nineteen aged 65 older hospitalized for surgery. Intervention: Participants were randomly assigned to daily (n=155) or usual care (n=164) during hospitalization the acute phase...
Abstract Background Patients with cancer have been shown to a higher risk of clinical severity and mortality compared non-cancer patients COVID-19. hematologic malignancies typically are known levels immunosuppression may develop more severe respiratory viral infections than solid tumors. Data on COVID-19 in limited. Here we characterize disease evaluate potential prognostic factors for mortality. Methods In this population-based registry study, collected de-identified data characteristics,...
OBJECTIVES: To analyze the effectiveness of a multicomponent intervention integrated into daily practice for prevention in‐hospital delirium in elderly patients. DESIGN: Controlled study comparing an geriatric unit (GI) with usual care two internal medicine services (UC). SETTING: University hospital Madrid, Spain. PARTICIPANTS: Five hundred forty‐two consecutive patients (170 GI, 372 UC), aged 70 and older, any risk criteria (cognitive impairment, visual acute disease severity,...
The clinical scenario of heart failure (HF) in older hospitalized patients is complex and influenced by acute chronic comorbidities, coexistent geriatric syndromes, the patient's ability for self-care after discharge, degree social support. impact all these factors on outcomes or disability evolution not sufficiently known. FRAIL-HF a prospective observational cohort study designed to evaluate (mortality readmission), functional evolution, quality life, use resources at 1, 3, 6, 12 months...
INTRODUCCIÓNLa fractura de la extremidad proximal del fémur o cadera (FC) es complicación más importante osteoporosis en términos mortalidad, morbilidad y costes (1).Puede producirse a cualquier edad pero aproximadamente el 90% los casos ocurren personas 64 años (2) teniendo cuenta las tendencias demográficas prever un aumento número fracturas próximos (3).Existen multitud trabajos que analizan incidencia FC tanto España (4-8) como resto Europa (9-11), Estados Unidos América (12), Asia...
The LIS2T study was an open-label, multicenter in which recipients of a primary liver transplant were randomized to cyclosporine microemulsion (CsA-ME) (Neoral) (n = 250) (monitoring blood concentration at 2 hours postdose) C2 or tacrolimus 245) trough drug level [predose]) C0 compare efficacy and safety 3 6 months evaluate patient status 12 months. All patients received steroids with without azathioprine. At months, 85% CsA-ME 86% survived functioning graft (P not significant). Efficacy...
Abstract Learning Objectives After completing this course, the reader will be able to: Use patient age as only one consideration, along with tumor status and comorbidities, in deciding on treatment strategies for elderly colorectal cancer patients.Obtain apply information regarding medical, functional, mental, social of patients order to make appropriate therapeutic decisions. CME This article is available continuing medical education credit at CME.TheOncologist.com Purpose. To analyze...
COVID-19 has overloaded national health services worldwide. Thus, early identification of patients at risk poor outcomes is critical. Our objective was to analyse SARS-CoV-2 RNA detection in serum as a severity biomarker COVID-19. Retrospective observational study including 193 admitted for Detection (viremia) performed with samples collected 48-72 h admission by two techniques from Roche and Thermo Fischer Scientific (TFS). Main outcome variables were mortality need ICU during...
Mortality rates for COVID-19 have declined over time in the general population, but data patients with hematologic malignancies are contradictory. We identified independent prognostic factors severity and survival unvaccinated malignancies, compared mortality versus non-cancer inpatients, investigated post condition. Data were analyzed from 1166 consecutive, eligible population-based HEMATO-MADRID registry, Spain, prior to vaccination roll-out, stratified into early (February-June 2020; n =...
Early kinetics of SARS-CoV-2 viral load (VL) in plasma determined by quantitative reverse-transcription polymerase chain reaction (RT-PCR) was evaluated as a predictor poor clinical outcome prospective study and assessed retrospective validation cohort. Prospective observational single-center including consecutive adult patients hospitalized with COVID-19 between November 2020 January 2021. Serial samples were obtained until discharge. Quantitative RT-PCR performed to assess VL. The main...
Helicobacter pylori (HP) infection has frequently been found in dialysis patients. Chronic infections induce overproduction of pro-inflammatory substances. Inflammation associated with cachexia and anorexia. We explored the relationship between HP infection, anorexia, malnutrition peritoneal (PD) patients.The study included 48 clinically stable PD patients divided into four groups: HP+ anorexia (group I, n = 12); without II, 4); HP- III, 5); IV, 27). Infection was diagnosed by breath test....
A greater understanding of clinical trends in COVID-19 outcomes among patients with hematologic malignancies (HM) over the course pandemic, particularly Omicron era, is needed. This ongoing, observational, and registry-based study prospective data collection evaluated severity mortality 1818 adult HM diagnosed between 27 February 2020 1 October 2022, at 31 centers Madrid region Spain. Of these, 1281 (70.5%) 537 (29.5%) were reported pre-Omicron periods, respectively. Overall, aged ≥70 years...
Human peritoneal function on commencing dialysis (PD) is not yet adequately understood. The objective of this study was to determine functional patterns PD.367 end-stage renal disease (ESRD) patients PD for the first time were studied between their initial second sixth weeks PD. Urea and creatinine mass transfer area coefficients (MTAC) standardized ultrafiltration (UF) capacity determined.Mean parametric values MTAC urea 22.9 +/- 7.04 mL/min, 10.31 4.68 UF 896 344 mL. Gender, patient size,...
Abstract Background The incorporation of genetic variables into risk scores for predicting venous thromboembolic events (VTE) could improve their capacity to identify those patients whom thromboprophylaxis would be most beneficial. Proof‐of‐concept this is provided by the TiC‐ONCO score VTE in with solid tumours. Our aim was develop a similarly improved tool—the TiC‐LYMPHO score—for lymphoma. Methods In retrospective observational study 208 lymphoma, 31 (14.9%) were found have experienced an...
Background: Interleukin 6 (IL6) levels and SARS-CoV-2 viremia have been correlated with COVID-19 severity. The association over time between them has not assessed in a prospective cohort. Our aim was to evaluate the relationship evolution of IL6 Methods: Secondary analysis from cohort including hospitalized patients Hospital Universitario La Princesa November 2020 January 2021. Serial plasma samples were collected admission until discharge. Viral load quantified by Real-Time Polymerase Chain...