Shalini Lynch

ORCID: 0000-0002-2569-7532
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About
Contact & Profiles
Research Areas
  • Pharmaceutical Practices and Patient Outcomes
  • Pharmaceutical industry and healthcare
  • Organ Transplantation Techniques and Outcomes
  • Pediatric health and respiratory diseases
  • Clostridium difficile and Clostridium perfringens research
  • Renal Transplantation Outcomes and Treatments
  • Ocular Diseases and Behçet’s Syndrome
  • Gut microbiota and health
  • Medical Research and Practices
  • Geriatric Care and Nursing Homes
  • Pharmaceutical Economics and Policy
  • Neonatal Respiratory Health Research
  • Probiotics and Fermented Foods
  • Pain Mechanisms and Treatments
  • Gastrointestinal motility and disorders
  • Reproductive Health and Contraception
  • Dementia and Cognitive Impairment Research
  • Hepatitis C virus research
  • Healthcare Systems and Technology
  • Advanced biosensing and bioanalysis techniques
  • Pharmaceutical studies and practices
  • Pain Management and Opioid Use
  • Asthma and respiratory diseases
  • Pediatric Pain Management Techniques
  • Health Systems, Economic Evaluations, Quality of Life

University of California, San Francisco
1995-2023

Alterations in the gut microbial community composition may be influential neurological disease. Microbial profiles were compared between early onset pediatric multiple sclerosis (MS) and control children similar for age sex.Children ≤18 years old within 2 of MS or controls without autoimmune disorders attending a University California, San Francisco, USA, clinic examined fecal bacterial predicted function by 16S ribosomal RNA sequencing phylogenetic reconstruction unobserved states (PICRUSt)...

10.1111/ene.13026 article EN European Journal of Neurology 2016-05-13

The LIS2T study was an open-label, multicenter in which recipients of a primary liver transplant were randomized to cyclosporine microemulsion (CsA-ME) (Neoral) (n = 250) (monitoring blood concentration at 2 hours postdose) C2 or tacrolimus 245) trough drug level [predose]) C0 compare efficacy and safety 3 6 months evaluate patient status 12 months. All patients received steroids with without azathioprine. At months, 85% CsA-ME 86% survived functioning graft (P not significant). Efficacy...

10.1002/lt.20802 article EN Liver Transplantation 2006-01-01

Abstract Introduction Potentially inappropriate medications (PIMs) cause adverse events and death. We evaluate the Care Ecosystem (CE) collaborative dementia care program on medication use among community‐dwelling persons living with (PLWD). Methods Secondary analysis of a randomized clinical trial (RCT) comparing CE to usual (UC) changes in PIMs, over 12 months between March 2015 May 2020. outcomes included change number medications, clinically relevant anti‐dementia medications. Results Of...

10.1002/alz.12808 article EN Alzheimer s & Dementia 2022-11-04

1. We studied the absorption of human calcitonin across colon juvenile female rats in vivo. Both pharmacokinetic and pharmacodynamic parameters were monitored to measure absorption. 2. Intracolonically administered at doses 0.1-5.0 mg/kg resulted a dose-dependent reduction plasma calcium levels. 3. The bioavailability intracolonically 5.0, 1.0 0.1 was 0.5%, 0.9% 0.2%, respectively. 4. Immunohistochemistry showed that transport rat rapid significant amount via transcellular pathway. 5....

10.1042/cs0820589 article EN Clinical Science 1992-05-01

Drug information (DI) services provided an avenue to expand the role of pharmacists as medication experts. The focus DI has shifted from general questions submitted centers patient-specific that optimize care. One method increase access pharmacist expertise is through pharmacy eConsults. Pharmacy eConsults provide specialist care for medically complex patients using a patient-centered, asynchronous approach. purpose this article describe evolution consults formal drug and one academic...

10.1177/87551225211049470 article EN Journal of Pharmacy Technology 2021-10-01

143 Vascular thrombosis represents the leading cause of non-immunologic pancreas graft loss with reported incidence ranging between 10-35%. Previously we had an 12% in our analysis from 1985-93, when CsA was mainstay immunosuppressive drug. Since then have changed to a tacrolimus (FK) based regimen and implemented prophylaxis using postoperative heparin ASA for majority recipients. To determine impact this, determined early (<3 months posttransplant) bleeding complication rates last 173...

10.1097/00007890-199810270-00173 article EN Transplantation 1998-10-01

The use of generic oral contraceptives (OCPs) can improve adherence and reduce healthcare costs, yet scepticism drugs remains a barrier to OCP discussion prescription. An educational web module was developed related OCPs, knowledge increase physician willingness discuss prescribe OCPs.A needs assessment completed using in-person focus groups at American College Physicians (ACP) Annual Meeting survey targeting baseline scepticism. Insights gained were used build an detailing barriers benefits...

10.1111/jcpt.12853 article EN Journal of Clinical Pharmacy and Therapeutics 2019-06-01

Although generic oral contraceptives (OCPs) can improve adherence and reduce health care expenditures, use of OCPs remains low, the factors that affect prescribing are not well understood. We aimed to understand barriers facilitators OCP potential solutions increase prescribing, as pilot an educational module address clinician misconceptions about OCPs. developed focus group scripts using 4D model appreciative inquiry. A total four groups occurred, two at American Association Nurse...

10.1097/jxx.0000000000000349 article EN Journal of the American Association of Nurse Practitioners 2019-12-06

TPS 631: Metals and health 1, Johan Friso Foyer, Floor August 27, 2019, 3:00 PM - 4:30 Background/Aim: The early life gut microbiome plays an essential role in throughout life, as it influences nutrient energy extraction, physiological growth, immune development. However, the impact of utero metal exposure on infant has not been well-characterized. aim this study was to assess association between fetal levels (manganese, lead, zinc) measured deciduous teeth bacterial microbiota at 1-...

10.1097/01.ee9.0000610136.89522.94 article EN cc-by-nc-nd Environmental Epidemiology 2019-10-01

Abstract Background The Care Ecosystem is a telephone‐based dementia care program that delivered by trained lay heath workers called Team Navigators (CTNs) who are supported and supervised clinical team with expertise in (Possin, et.al., 2019). We hypothesized health systems interested implementing the would benefit from an asynchronous online training course to help prepare dementia‐capable workforce. Method With grant Merck Foundation, faculty staff UCSF Memory Aging Center UC Hastings...

10.1002/alz.041596 article EN Alzheimer s & Dementia 2020-12-01
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