A5044281244- Central Venous Catheters and Hemodialysis
- Nosocomial Infections in ICU
- Bacterial Identification and Susceptibility Testing
- Infective Endocarditis Diagnosis and Management
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Pneumonia and Respiratory Infections
- Infection Control in Healthcare
- Vascular Procedures and Complications
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Bacterial biofilms and quorum sensing
- Surgical site infection prevention
- Hemodynamic Monitoring and Therapy
- Urinary Tract Infections Management
- Healthcare Decision-Making and Restraints
- Patient Satisfaction in Healthcare
- Long-Term Effects of COVID-19
- Sepsis Diagnosis and Treatment
- SARS-CoV-2 detection and testing
- Antibiotic Resistance in Bacteria
- Antibiotics Pharmacokinetics and Efficacy
Hospital General Universitario Gregorio Marañón
2016-2025
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2016-2025
Hospital Universitario Doctor Peset
2025
Universidad Complutense de Madrid
2014-2024
Instituto de Investigación Biomédica de Salamanca
2024
Centro de Investigación Biomédica en Red de Cáncer
2024
Hospital Universitario Ramón y Cajal
1997-2023
Centro de Investigación Biomédica en Red
2014-2023
Instituto Ramón y Cajal de Investigación Sanitaria
2023
Hospital de Sant Pau
2021
Abstract Background There is a paucity of knowledge on the long-term outcome in patients diagnosed with COVID-19. We describe cohort constellation symptoms occurring four weeks after diagnosis causing different degrees reduced functional capacity. Although hypothesis have been proposed to explain this condition like persistent immune activation or immunological dysfunction, date, no physiopathological mechanism has identified. Consequently, there are therapeutic options besides symptomatic...
Suspicion of catheter-related bloodstream infection (CR-BSI) leads frequently to unnecessary catheter withdrawals, and many catheter-tip cultures yield negative results. The objective this study was compare the 3 microbiological procedures assess CR-BSI without withdrawal.The prospectively performed in a group patients neutropenia or blood disorders who were admitted intensive care unit during 37-month period with sepsis suspected on clinical grounds had central venous catheters inserted for...
Abstract Purpose. To assess the usefulness of sonographic measurement median nerve cross‐sectional area (CSA) in diagnosis carpal tunnel syndrome (CTS) and grading its severity using conduction (NC) studies as standard. Method. The CSA was measured at inlet outlet ellipse formula automatic tracing 72 hands with suspicion CTS. Result. lack inter‐reader reliability led to excluding measurements obtained outlet. Based on receiver operating characteristic curves, following cut‐off points for...
To determine the frequency, etiology, and risk factors of ventilator-associated pneumonia (VAP) purulent tracheobronchitis (TBX) in patients who have undergone heart surgery. study predictive role systematic surveillance cultures.Prospective study.Heart surgery intensive care unit.Intubated surgical patients.Systematic tracheal aspirate protected brush catheter cultures all intubated patients.Studied were frequency lower respiratory tract infection ventilated cultures. The VAP was 7.87%...
Background. Demonstration of catheter tip colonization is usually performed by use Maki's semiquantitative technique, although the superiority quantitative techniques has been claimed on basis their purported ability to detect both endoluminal and exoluminal microorganisms.
We assessed the potential role of T2Candida MR (T2MR) and serological biomarkers [β-d-glucan (BDG) or Candida albicans germ tube antibodies (CAGTA)], alone in combination with standard cultures, for identifying patients suspected invasive candidiasis (IC), who may benefit from maintaining antifungal therapy.Prospective observational multicentre study including all adult receiving empirical therapy IC, January to June 2017. CAGTA, BDG T2MR were determined at baseline +2 +4 days after...
Abstract Background At some point in their lives, many people will require major heart surgery (MHS). Patients are generally older adults with various risk factors for infection. However, the incidence of infection after MHS is poorly known, as reported data frequently biased due to different like surgical procedure, postoperative timing, and infectious syndromes or etiologic agents, among others. In addition, most patient retrospectively obtained. Purpose methods Data were prospectively...
Diagnosis of complicated candidaemia represents a challenge for clinicians since early clinical manifestations may be non-specific and difficult to identify, thus precluding an appropriate treatment.This was multicentre prospective study predicting episodes in patients with bloodstream infection caused by Candida species, while assessing the value follow-up blood cultures (BCs) persistence positive results T2Candida MR (T2MR) β-d-glucan (BDG) tests. Immediately after first BC yielding...
ABSTRACT The differential time to positivity (DTTP) technique is the recommended conservative procedure diagnose catheter-related bloodstream infection (C-RBSI). However, its reliability and accuracy remain under debate. Therefore, we aimed compare DTTP feasibility detect C-RBSI compared catheter culture (CC) method. We conducted a 9-month retrospective study including bacteremic episodes in which both blood cultures (BC) CC were obtained. analyzed diagnostic validity of for detecting gold...
Abstract Background Currently, medical therapy of Crohn’s disease (CD) can reduce the progression some forms structural bowel damage (SBD), but it does not prevent it. Once SBD has developed, is important to assess potential treatments reverse this damage. Aims To determine whether transmural healing (TH), assessed by intestinal ultrasonography (IUS), be achieved with treatment in CD patients compared those without. Methods A prospective, longitudinal, observational study was conducted...
After an educational intervention in 3 intensive care units, 34 central line-associated bloodstream infections occurred 11,582 venous catheter [CVC]-days, compared with 45 episodes 10,661 CVC-days before (4.22 vs 2.94 per 1,000 [30.9% reduction]; P = .03, Wilcoxon rank sum test; .11, Poisson regression analysis).