Sonia González
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Viral-associated cancers and disorders
- SARS-CoV-2 detection and testing
- Chronic Lymphocytic Leukemia Research
- Pancreatitis Pathology and Treatment
- Renal function and acid-base balance
- Heart Failure Treatment and Management
- Lymphoma Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Amoebic Infections and Treatments
- Long-Term Effects of COVID-19
Instituto de Investigación Marqués de Valdecilla
2025
Hospital Universitario de Guadalajara
2022
Hospital Universitario de La Princesa
2020-2021
BackgroundPatients with coronavirus disaese 2019 (COVID-19) can develop a cytokine release syndrome that eventually leads to acute respiratory distress requiring invasive mechanical ventilation (IMV). Because IL-6 is relevant in syndrome, the blockade of its receptor tocilizumab (TCZ) could reduce mortality and/or morbidity severe COVID-19.ObjectiveWe sought determine whether baseline serum levels predict need for IMV and response TCZ.MethodsA retrospective observational study was performed...
COVID-19 has overloaded national health services worldwide. Thus, early identification of patients at risk poor outcomes is critical. Our objective was to analyse SARS-CoV-2 RNA detection in serum as a severity biomarker COVID-19. Retrospective observational study including 193 admitted for Detection (viremia) performed with samples collected 48-72 h admission by two techniques from Roche and Thermo Fischer Scientific (TFS). Main outcome variables were mortality need ICU during...
Diffuse Large B-Cell Lymphoma (DLBCL) is a heterogeneous disease characterized by limited number of molecularly defined subtypes. Recently, genomic-based algorithms have been proposed for the classification this disease. The whole exome sequencing was conducted on 108 diagnostic samples diffuse large B-cell lymphoma (DLBCL). Somatic variants, predicted copy alterations (CNAs), and available fusion data were utilized to classify cases. Additionally, enrichment mutations in TP53, MYC, MAPK/ERK...
<title>Resumen</title> En el presente manuscrito, se ha recogido un caso de absceso hepático posiblemente causado por una colecistitis evolucionada, en la que está implicado germen anaerobio, fusobacterium mortiferum, no descrito literatura como agente causal este tipo infecciones. Al tener infección presencia bacteria infrecuente paciente con diagnóstico COVID 19, podemos postular posibilidad estado inmunológico del al presentar enfermedad haya podido inducir o simplemente ser 2 hechos...