A5026698516- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical studies and practices
- Antibiotic Use and Resistance
- Medication Adherence and Compliance
- Patient Safety and Medication Errors
- Pharmacovigilance and Adverse Drug Reactions
- Patient Satisfaction in Healthcare
- Primary Care and Health Outcomes
- Blood Pressure and Hypertension Studies
- Healthcare cost, quality, practices
- Health Policy Implementation Science
- Interprofessional Education and Collaboration
- Schizophrenia research and treatment
- Heart Failure Treatment and Management
- Geriatric Care and Nursing Homes
- Chronic Disease Management Strategies
- Atrial Fibrillation Management and Outcomes
- Healthcare Quality and Management
- Dementia and Cognitive Impairment Research
- Healthcare Policy and Management
- Healthcare professionals’ stress and burnout
- Pharmacy and Medical Practices
- Palliative Care and End-of-Life Issues
- Pharmaceutical Economics and Policy
University College Cork
2016-2025
Shionogi (Japan)
2025
Cork University Hospital
2008-2023
National University of Ireland
2018-2023
Transport Infrastructure Ireland
2020-2023
University of Limerick
2023
Mater Private Hospital
2021
University Hospitals Bristol NHS Foundation Trust
2020
Shannon Applied Biotechnology Centre
2020
Intel (United Kingdom)
2020
<h3>Background</h3> Previous studies have not demonstrated a consistent association between potentially inappropriate medicines (PIMs) in older patients as defined by Beers criteria and avoidable adverse drug events (ADEs). This study aimed to assess whether PIMs new STOPP (Screening Tool of Older Persons' Prescriptions) are significantly associated with ADEs people acute illness. <h3>Methods</h3> We prospectively studied 600 consecutive 65 years or who were admitted illness university...
The use of levothyroxine to treat subclinical hypothyroidism is controversial. We aimed determine whether provided clinical benefits in older persons with this condition.
* Potentially inappropriate prescribing in older people is a well-documented problem and has been associated with adverse drug reactions hospitalization. Beers' criteria, Screening Tool of Older Persons' potentially Prescriptions (STOPP) to Alert doctors Right Treatment (START) are screening tools that have formulated help physicians pharmacists identify potential omissions. The prevalence omissions the elderly population presenting hospital acute illness high according STOPP START...
Abstract Objective To examine the effect of optimising drug treatment on related hospital admissions in older adults with multimorbidity and polypharmacy admitted to hospital. Design Cluster randomised controlled trial. Setting 110 clusters inpatient wards within university based hospitals four European countries (Switzerland, Netherlands, Belgium, Republic Ireland) defined by attending doctors. Participants 2008 (≥70 years) (≥3 chronic conditions) (≥5 drugs used long term). Intervention...
Objectives To determine whether use of the Screening Tool Older Persons' Prescriptions ( STOPP ) and to Alert Right Treatment START criteria reduces incident hospital‐acquired adverse drug reactions ADR s), 28‐day medication costs, median length hospital stay in older adults admitted with acute illness. Design Single‐blind cluster randomized controlled trial RCT unselected hospitalized over a 13‐month period. Setting Tertiary referral southern Ireland. Participants Consecutively individuals...
To explore healthcare professionals' views of antibiotic prescribing in long-term care facilities (LTCFs). use the findings to recommend intervention strategies for antimicrobial stewardship LTCFs.Qualitative semistructured interviews were conducted. The data analysed by thematic content analysis. After interviews, emerging mapped theoretical domains framework (TDF), and behaviour change wheel technique (BCT) taxonomy used future strategies.Interviews conducted with 37 professionals who work...
Multi-morbidity and polypharmacy increase the risk of non-trivial adverse drug reactions (ADRs) in older people during hospitalization. Despite this, there are no established interventions for hospital-acquired ADR prevention.We undertook a pragmatic, multi-national, parallel arm prospective randomized open-label, blinded endpoint (PROBE) controlled trial enrolling patients at six European medical centres. We 1,537 surgical with multi-morbidity on admission 1:1 ratio to SENATOR...
Background: adverse drug reactions (ADRs) are a major cause of morbidity and healthcare utilisation in older people. The GerontoNet ADR risk score aims to identify people at ADRs during hospitalisation. We aimed assess the clinical applicability this other variables that predict hospitalised Methods: we prospectively studied 513 acutely ill patients aged ≥65 years. was calculated for all patients. were identified through patient physician consultation together with analysis case notes....
Pharmacist interventions are one of the pivotal parts a clinical pharmacy service within hospital. This study estimates cost avoidance generated by pharmacist due to prevention adverse drug events (ADE). The types identified also analysed. Interventions recorded team hospital pharmacists over year time period were included in study. assigned rating score, determined probability that an ADE would have occurred absence intervention. These scores then used calculate avoidance. Net benefit and...
Information about antibiotic prescribing practice in primary care is not available for Ireland, unlike other European countries. The study aimed to ascertain the types of antibiotics and corresponding conditions seen whether general practitioners (GPs) felt that an was necessary at time consultation. This information will be vital inform future initiatives prudent care.Participating GPs gathered data on all prescribed by them 100 consecutive patients' consultations as well being treated they...
potentially inappropriate prescribing (PIP) is a significant problem in health care today. We hypothesise that if doctors were given single indicator of PIP and adverse drug reaction (ADR) risk on patient's prescription, it might stimulate them to review the medicines. suggest frailty index (FI) score may be such suitable indicator.to determine whether positive relationship exists between status, appropriateness their medications propensity develop ADRs. Compare this just using number...
Background: STOPP/START was formulated to identify potentially inappropriate prescribing (PIP) and potential omissions (PPOs) in older people. The purpose of this study determine the prevalence PIP PPO Irish patients residential care using STOPP/START. Methods: data were collected prospectively from seven publicly funded nursing homes within Munster Region Ireland over 3 weeks. Data recorded included: current medication, medical conditions, previous biochemistry, sex age. applied each...