A5082135679- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Delphi Technique in Research
- Cardiac, Anesthesia and Surgical Outcomes
- Patient Safety and Medication Errors
- Pharmacovigilance and Adverse Drug Reactions
- Dialysis and Renal Disease Management
- Pharmaceutical studies and practices
- Medication Adherence and Compliance
- Health, Medicine and Society
- Health Policy Implementation Science
- Electrolyte and hormonal disorders
- Chronic Disease Management Strategies
- Patient-Provider Communication in Healthcare
UCLouvain
2016-2022
Solvay (Belgium)
2022
AZ Sint-Lucas
2021
University College London
2015
Abstract Objective To examine the effect of optimising drug treatment on related hospital admissions in older adults with multimorbidity and polypharmacy admitted to hospital. Design Cluster randomised controlled trial. Setting 110 clusters inpatient wards within university based hospitals four European countries (Switzerland, Netherlands, Belgium, Republic Ireland) defined by attending doctors. Participants 2008 (≥70 years) (≥3 chronic conditions) (≥5 drugs used long term). Intervention...
Comparisons of clinical trial findings in systematic reviews can be hindered by the heterogeneity outcomes reported. Moreover, that matter most to patients might underreported. A core outcome set address these issues, as it defines a minimum should reported all trials particular area research. The objective this study was develop for medication review multi-morbid older with polypharmacy. Firstly, eligible were identified through (≥65 years) and interviews 15 patients. Secondly, an...
We aimed to develop a standardized chart review method identify drug-related hospital admissions (DRA) in older people caused by non-preventable adverse drug reactions and preventable medication errors including overuse, underuse misuse of medications: the DRA adjudication guide.The guide was developed based on design test iterations with international multidisciplinary input four subsequent steps: literature review; evaluation content validity using Delphi consensus technique; pilot test;...
Background A patient-centred approach to medicines optimisation is considered essential. The OPtimising thERapy prevent Avoidable hospital admissions in Multimorbid older people (OPERAM) trial evaluated the effectiveness of medication review with shared decision-making (SDM) multimorbidity. Beyond evaluating clinical effectiveness, exploring patient experience facilitates a better understanding contextual factors and mechanisms affecting effectiveness. Objective To explore experiences...
Abstract Background identifying drug-related hospital admissions (DRAs) in older people is difficult. A standardised chart review procedure has recently been developed. It includes an adjudication team (physician and pharmacist) screening using 26 triggers then performing causality assessment to determine whether adverse drug event (ADE) occurred (secondary reaction, overuse, misuse or underuse) the ADE contributed admission (DRA). Objective assess performance of those detecting DRA. Design...
Background: Medication review has been advocated to address the challenge of polypharmacy in older patients, yet there is no consensus on how best evaluate its efficacy. Heterogeneity outcomes reported clinical trials can hinder comparison trial findings systematic reviews. Moreover, that matter most patients might be under-reported or disregarded altogether. A core outcome set this issue as it defines a minimum should all any particular field research. As part European Commission-funded...
<h3>Background</h3> Intravenous (IV) fluid treatment is a routine but essential part of care for significant proportion hospitalised patients. However one in five patients suffer from fluid-related complications with associated morbidity and mortality. In 2013, NICE clinical guideline was published the aim improving IV management. A lack knowledge identified as key factor contributing to poor <h3>Purpose</h3> To assess among nurses, junior doctors pharmacists adults. Knowledge assessed daily...