A5021297392- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- RNA Research and Splicing
- Photosynthetic Processes and Mechanisms
- Sulfur Compounds in Biology
- Wnt/β-catenin signaling in development and cancer
- Cardiomyopathy and Myosin Studies
- Mitochondrial Function and Pathology
- Receptor Mechanisms and Signaling
- Phosphodiesterase function and regulation
- Porphyrin and Phthalocyanine Chemistry
- Peptidase Inhibition and Analysis
- Metabolism and Genetic Disorders
- Molecular Sensors and Ion Detection
- Cancer-related gene regulation
- Magnetism in coordination complexes
- Cardiac Fibrosis and Remodeling
- Cardiac Arrhythmias and Treatments
- Amino Acid Enzymes and Metabolism
- RNA and protein synthesis mechanisms
- Luminescence and Fluorescent Materials
Imperial College London
2019-2023
University of Bath
2018
A novel fluorescence-based scaffold was developed enabling the production of ‘AND’ based fluorescence probes – ROS/RNS and a second analyte.
Abstract The Popeye domain containing (POPDC) genes encode sarcolemma-localized cAMP effector proteins. Mutations in blood vessel epicardial substance ( BVES ) also known as POPDC1 and POPDC2 have been associated with limb-girdle muscular dystrophy cardiac arrhythmia. Muscle biopsies of affected patients display impaired membrane trafficking both POPDC isoforms. Biopsy material carrying mutations were immunostained antibodies. interaction proteins was investigated by co-precipitation,...
A novel approach to axially induce chirality on silicon phthalocyanines via a microwave-assisted route is reported. CD analysis provides spectroscopic evidence that transferred onto both Soret and Q-bands of the phthalocyanine core. chiral naphthalenediimide ligand was found largest Cotton effect macrocycle absorptions.
Abstract Background The Popeye domain containing (POPDC) genes encode sarcolemma-localised cAMP effector proteins. Mutations in BVES (POPDC1) and POPDC2 have been associated with limb-girdle muscular dystrophy cardiac arrhythmia. Muscle biopsies of affected patients display impaired membrane trafficking both POPDC isoforms. Methods Biopsy material carrying mutations were immunostained antibodies. interaction proteins was investigated by co-precipitation, proximity ligation, bioluminescence...