- Congenital Heart Disease Studies
- Mechanical Circulatory Support Devices
- Cardiac Arrhythmias and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Central Venous Catheters and Hemodialysis
- Cardiac Valve Diseases and Treatments
- Pleural and Pulmonary Diseases
- Aortic Disease and Treatment Approaches
- Vascular Procedures and Complications
- Colorectal Cancer Screening and Detection
- Trauma Management and Diagnosis
- Cardiac, Anesthesia and Surgical Outcomes
- Infant Development and Preterm Care
- Analytical Methods in Pharmaceuticals
- Genetic factors in colorectal cancer
- Tracheal and airway disorders
- Childhood Cancer Survivors' Quality of Life
- Ultrasound in Clinical Applications
- Cardiovascular Function and Risk Factors
- Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Colorectal Cancer Treatments and Studies
- Pharmacogenetics and Drug Metabolism
- Hemodynamic Monitoring and Therapy
Prince of Songkla University
2014-2025
Background: Oxidative stress and systemic inflammation during cardiac surgery can lead to postoperative complications. Although vitamin C thiamine (vitamin B1) have individually demonstrated protective effects, their combined effects remain underexplored. This study aimed evaluate the efficacy of B1 therapy versus that alone in reducing inflammatory biomarkers improving outcomes patients undergoing surgery. Methods: In this prospective, double-blind, randomized controlled trial, 64 scheduled...
Background: The study aimed to determine the incidence of K-ras and BRAF mutations in colorectal cancers (CRCs) Thai patients evaluate association with clinicopathological parameters including treatment outcomes terms event free survival (EFS). Materials Methods: Two-hundred cancer specimens were collected for studies K-Ras codon 12, 13 61, 600 by polymerase chain reaction direct nucleotide sequencing. Results: overall our was 23%. mutation frequencies CRC stages (AJCC) I, II, III IV 6.7%,...
To determine the association between several perioperative variables and in-hospital shunt thrombosis mortality in patients weighing less than 3 kg with functional univentricular heart (UVH) who underwent modified Blalock-Taussig shunt.Between January 2006 February 2016, 85 weighed UVH were reviewed. In-hospital primary outcomes. The associations outcomes assessed univariate multivariate analyses.In-hospital was 14% (12 of 85). Hospital 18% (15 85), which resulted an 82% discharge survival...
Objective To determine risk factors affecting time-to-death ≤90 and >90 days in children who underwent a modified Blalock-Taussig shunt (MBTS). Methods Data from retrospective cohort study were obtained aged 0–3 years experienced MBTS between 2005 2016. Time-to-death (prior to Glenn/repair), time-to-alive up until December 2017 without repair, time-to-progression Glenn/repair following presented using competing risks survival analysis. Demographic, surgical anesthesia-related recorded....
Background: Many cases of chronic thoracic central vein occlusion (CVO) fail to recanalize using the standard conventional guidewire technique. This study aims present outcomes sharp recanalization with a transseptal needle in CVO. Methods: retrospective involved 22 hemodialysis patients who developed clinical signs and symptoms CVO, had unsuccessful endovascular treatment guidewire, underwent from January 2018 December 2021. Demographic information patients, technical success rate,...
Post-pneumonectomy bronchopleural fistula (PPBPF) is a devastating complication in thoracic surgery, with reported incidences varying from 3.1% to 20% (1-3). The diversity of incidence depends on number factors including malignancy or benign conditions and the extent resection technique used (4).
Background: Pharmacodynamics of warfarin are influenced by genetic polymorphisms its metabolic enzymes. Objectives: To determine CYP2C9 and VKORC1 genotypes in a population southern Thailand, their association with maintenance doses. Methods: We genotyped CYP2C9*2 (rs1799853), CYP2C9*3 (rs1057910), (rs9923231 rs9934438) from the blood DNA 210 healthy controls, determined 2 polymorphic markers (CYP2C9*3 rs9923231) 154 patients aortic valve protheses, dose coagulopathy. Results: was detected...
Background: Transcatheter aortic valve implantation (TAVI) has been shown to be effective in treating patients with severe symptomatic AS who are high-risk population for conventional surgical replacement (SAVR). This study aimed evaluate the cost–utility of TAVI compared SAVR stenosis high risk Thailand. Methods: Lifetime costs and quality-adjusted life years (QALYs) from societal healthcare perspectives were estimated using a two-part constructed model. The consisted 80-year-old risk....
Objectives: Post-pneumonectomy bronchopleural fistula (PPBPF) is a severe complication when it associated with empyema. Such complicated PPBPF usually results in prolonged hospital stay, high morbidity and mortality. The objective of the study was to report our early experience initiation autogenous corticocancellous bone graft treatment PPBPF. technique used an aim provide oeteoinduction tracheal mucosa, minimise risk infection. Methods: Between June 2011 September 2013, use initiated 4...
Background: Studies on predictors of health-related quality life (HRQOL) in pediatric patients with cyanotic heart disease who are waiting for the next stage and those have undergone total repair scarce. Therefore, we aimed to identify such children received modified Blalock–Taussig shunt (MBTS) underwent repair. Methods: In this historical cohort concurrent follow-up study, data MBTS at age 0–3 years between January 2005 December 2016 a super-tertiary care hospital Southern Thailand were...
Transcatheter Aortic Valve Implantation (TAVI) has been shown to provide comparable survival benefit and improvement in quality of life surgical aortic valve replacement (SAVR) for treating patients with severe stenosis (AS) at intermediate risk. This study aimed evaluate the cost-utility TAVI compared SAVR risk Thailand.A two-part constructed model was used analyze lifetime costs quality-adjusted life-years (QALYs) from societal healthcare perspectives. The cohort comprised AS an average...
Objective Extracorporeal membrane oxygenation (ECMO) is a relatively new technology used for life support in patients with cardiopulmonary failure from various causes. The objective of this study to review the first 5-year experience adopting teaching hospital southern Thailand. Methods data ECMO-supported Songklanagarind Hospital, years 2014 2018, were retrospectively reviewed. Data sources electronic medical records and database perfusion service. Parameters focus included prior conditions...
Background A few prognostic scoring systems have been developed for predicting mortality in patients with cardiogenic shock requiring veno-arterial extracorporeal membrane oxygenation (VA-ECMO), albeit variations performance. This study aimed to assess and compare various prediction models a cohort of receiving VA-ECMO following or arrest. Methods We retrospectively analyzed 77 who were placed on support between March 2014 August 2021. The APACHE II, SAPS SAVE, Modified ENCOURAGE,...