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Sarah K. Read

ORCID: 0000-0003-2185-0082
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About
Contact & Profiles
A5101594253
Research Areas
  • Abdominal vascular conditions and treatments
  • Hypertrophic osteoarthropathy and related conditions
  • Dermatological and Skeletal Disorders
  • Pluripotent Stem Cells Research
  • Renal and related cancers
  • Tissue Engineering and Regenerative Medicine

Biogen (United States)
 2017

 Hyperactive FOXO1 results in lack of tip stalk identity and deficient microvascular regeneration during kidney injury
OPENALEX - Publications 
Lan Dang Takahide Aburatani Graham Marsh Bryce G. Johnson Stella Alimperti and 13 more Christine Yoon Angela Huang Suzanne Szak Naoki Nakagawa Ivan G. Gomez Shuyu Ren Sarah K. Read Christopher Sparages Alfred C. Aplin Roberto F. Nicosia Christopher S. Chen Giovanni Ligresti Jeremy S. Duffield

Loss of the microvascular (MV) network results in tissue ischemia, loss function, and is a hallmark chronic diseases. The incorporation functional vascular with that host remains challenge to utilizing engineered tissues clinically relevant therapies. We showed vascular-bed-specific endothelial cells (ECs) exhibit differing angiogenic capacities, kidney (MVECs) being most deficient, sought explore underlying mechanism. Constitutive activation phosphatase PTEN MVECs resulted impaired PI3K/AKT...

10.1016/j.biomaterials.2017.07.010 article EN cc-by-nc-nd Biomaterials 2017-07-07
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