A5101635664- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- ECG Monitoring and Analysis
- Venous Thromboembolism Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood Pressure and Hypertension Studies
- Cardiovascular Disease and Adiposity
- Cardiac Valve Diseases and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Heart Rate Variability and Autonomic Control
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Nutritional Studies and Diet
- Cerebrovascular and Carotid Artery Diseases
- Diabetes Treatment and Management
- Hormonal Regulation and Hypertension
- Diet and metabolism studies
- Long-Term Effects of COVID-19
- Cardiovascular Health and Disease Prevention
- Soybean genetics and cultivation
- Acute Ischemic Stroke Management
Ewha Womans University
2016-2025
Kyungpook National University
2022-2025
Ewha Womans University Medical Center
2015-2024
Emory University
2024
Seoul National University
2024
Yonsei University
2011-2023
Baewha Women's University
2023
Dalian Medical University
2023
Chongqing Medical University
2023
Second Affiliated Hospital of Chongqing Medical University
2023
For healthy populations without comorbidities, whether prehypertension and impaired fasting glucose (IFG) are associated with new onset atrial fibrillation (AF) is not well known. We included 366 507 subjects (age ≥20 years) diagnosed non-valvular AF from the Korean National Health Insurance Service-National Sample Cohort (NHIS-NSC) 2003 to 2008. In total, 139 306 AF-related comorbidities were excluded, a 227 102 population was followed up until 2013. The body mass index (BMI), blood...
Background Higher height and weight are known to be associated with higher risk of atrial fibrillation ( AF ); however, whether the is related abdominal obesity unclear. Methods Results We studied 501 690 adults (mean age: 47.6±14.3 years; 250 664 women [50.0%]) without baseline in National Sample Cohort released by Health Insurance Service Korea. Body mass index (underweight defined as <18.5; normal, 18.5 <25.0; overweight, 25.0 <30.0; obese, ≥30.0) waist circumference (abdominal...
Importance Discontinuation of oral anticoagulant treatment is common in clinical practice due to concerns about bleeding, even for procedures with minimal low bleeding risk. Objective To explore whether perioperative discontinuation factor Xa inhibitors associated major and thromboembolic events patients atrial fibrillation (AF) undergoing Design, Setting, Participants This prospective, multicenter, single-arm cohort study conducted Korea included AF who planned undergo a procedure risk...
AimsWe hypothesized that P-wave amplitude in lead I is related to left atrial (LA) remodelling and inter-atrial conduction pattern, has a predictive value for recurrence after radiofrequency catheter ablation (RFCA) among patients with paroxysmal fibrillation (PAF).
Purpose: Label adherence for non-vitamin K antagonist oral anticoagulants (NOACs) has not been well evaluated in Asian patients with non-valvular atrial fibrillation (AF).The present study aimed to assess label NOACs a Korean AF population and determine risk factors of off-label prescriptions NOACs. Materials Methods:In this COmparison Drugs symptom control complication prEvention (CODE-AF) registry, who were prescribed between June 2016 May 2017 included.Four NOAC doses categorized as on-or...
Although electrically reconnected pulmonary veins (PV) are the main mechanism of atrial fibrillation (AF) recurrence, PV isolation (PVI) is well-preserved in certain patients who undergo a repeat procedure. We explored association between reconnection and clinical outcomes after second ablation.This observational cohort study included 143 (79.0% male, 56.1 ± 10.0 years old, 65.0% paroxysmal AF) underwent Pulmonary vein was well-maintained 52 (PVP- group, 36.4%), although remaining 91 showed...
Machine learning (ML) and large-scale big data are key factors in developing an accurate prediction model for cardiovascular disease (CVD). Although the CVD risk often depends on race ethnicity, most previous studies considered only US or European populations prediction. In this work, to complement researches, we analyzed Korean National Health Insurance Service-National Sample Cohort (KNHSC) studied characteristics of ML predicting risk. More specifically, assessed effectiveness various...
Background A prolonged PR interval is known to be a poor prognostic factor in cardiovascular disease. The aim of this study was investigate the association between and clinical outcome patients undergoing radiofrequency catheter ablation ( RFCA ) atrial fibrillation AF ). Methods Results We prospectively included 576 with (75.5% male, 57.8±11.6 years old, 68.8% paroxysmal who underwent . analyzed preprocedural sinus rhythm ECG s obtained absence antiarrhythmic drug, all enrolled were...
Atrial fibrillation (AF) type can vary depending on condition and timing, some patients who initially present with persistent AF may be changed to paroxysmal after antiarrhythmic drug medication cardioversion. We investigated whether circumferential pulmonary vein isolation (CPVI) alone is an effective rhythm control strategy in AF.We enrolled 113 (male 75%, 60.4±10.1 years old) underwent catheter ablation for nonvalvular at 3 tertiary hospitals. The participants were randomly assigned 2...
Background: Persistent atrial fibrillation (AF) can change to paroxysmal AF after antiarrhythmic drug medication and cardioversion. We investigated whether electrical posterior box isolation (POBI) may improve rhythm outcome of catheter ablation in those patient groups. Methods: prospectively randomized 114 patients with persistent (men, 75%; 59.8±9.9 years old) circumferential pulmonary vein (CPVI) alone group (n=57) additional POBI (n=57). Primary end point was recurrence a single...
Background: Acute respiratory viral infections can result in cardiovascular involvement, with such patients having a significantly higher mortality rate than those without involvement. Due to the ongoing coronavirus disease 2019 (COVID-19) pandemic, it is important determine whether risk factors are associated severity of COVID-19. Methods: These nationwide data were provided by Korea Disease Control and Prevention Agency. We defined patient as “critical illness” if they required more...
Background The purpose of the RAFAS (Risk and Benefits Urgent Rhythm Control Atrial Fibrillation in Patients With Acute Stroke) trial was to explore risks benefits early rhythm control patients with newly documented atrial fibrillation (AF) during an acute ischemic stroke (IS). Method Results An open‐label, randomized, multicenter design used. If AF diagnosed, group started within 2 months after occurrence IS, unlikely usual care. primary end points were recurrent IS 3 12 months. secondary a...
Although the concept of radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) was derived from maze surgery, it is unclear if linear in addition to circumferential pulmonary vein isolation (CPVI) reduces recurrence rate patients with paroxysmal AF. Therefore, we compared clinical outcomes CPVI additional ablations (Dallas lesion set) and a prospective randomized controlled study among This enrolled 100 AF (male 75.0%, 56.4 ± 11.6 years old) who underwent RFCA were randomly...
Background It is not clear whether bidirectional block ( BDB ) of linear ablations reduces atrial fibrillation AF recurrence after radiofrequency catheter ablation. We hypothesized that ablation has prognostic significance for persistent . Methods and Results Among 1793 consecutive patients in the Yonsei cohort, this observational cohort study included 398 with (75.6% male; age, 59.8±10.3 years) who underwent a consistent protocol Dallas lesion set: circumferential pulmonary vein isolation;...
Background/Objectives The relationship between body mass index (BMI) and mortality remains controversial. Furthermore, the association BMI cardiovascular events (CVE) is not conclusive may differ by ethnicity. We aimed to estimate associations or disease in a general Korean population. Subjects/Methods This study was based on sample cohort database released National Health Insurance Service. analyzed total of 415,796 adults older than 30 years age who had undergone national health...
Soybean is particularly known for accumulating saponins in its seeds. This study aimed to identify a causal gene control an increase Ab-γg saponin PE1607 from EMS-treated population of the soybean cultivar Pungsannamul. Segregation analysis F2 seeds verified that single recessive allele controlled increased PE1607. Bulk segregant and mutant individuals identified candidate region, containing previously reported Sg-3 (Glyma.10G104700) gene, encoding glucosyltransferase responsible conjugating...
Background and Objectives:The aging population is rapidly increasing, atrial fibrillation (AF) becoming a significant public health burden in Asia, including Korea.This study evaluated current treatment patterns guideline adherence of AF treatment.Methods: In prospective observational registry (COmparison Drugs for symptom control complication prEvention Atrial Fibrillation [CODE-AF] registry), 6,275 patients with nonvalvular were consecutively enrolled between June 2016 April 2017 from 10...
Abstract Aims Although a recent expert consensus statement has recommended periprocedural uninterrupted (UI) non-vitamin K antagonist oral anticoagulants (NOACs) during catheter ablation of atrial fibrillation (AF) as Class I indication, there have been no clear randomized trials. We investigated the safety and efficacy UI, procedure day single-dose skipped (SDS), 24-hour (24S) NOACs in patients undergoing AF ablation. Methods results In this prospective, open-label, multicentre trial, 326...
Introduction The presence of late gadolinium enhancement (LGE) at the right ventricular insertion point (RVIP) on cardiac magnetic resonance (CMR) is generally believed to be nonspecific, but clinical implication this unique LGE pattern in patients with non-ischemic dilated cardiomyopathy (NICM) has not been elucidated. Objectives We investigated prognostic significance RVIP-LGE NICM patients. Methods A total 360 consecutive referred for CMR (102 no LGE, 50 RVIP-LGE, 121 left [LV]-LGE, and...