- Animal Disease Management and Epidemiology
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Microbial infections and disease research
- Influenza Virus Research Studies
- Diabetes and associated disorders
- Malaria Research and Control
- Immune Cell Function and Interaction
- Zoonotic diseases and public health
- Vector-Borne Animal Diseases
- Pancreatic function and diabetes
- Animal Virus Infections Studies
- Salmonella and Campylobacter epidemiology
- COVID-19 epidemiological studies
- Animal Behavior and Welfare Studies
- Tuberculosis Research and Epidemiology
- Animal Nutrition and Physiology
- Viral gastroenteritis research and epidemiology
- Milk Quality and Mastitis in Dairy Cows
- Data-Driven Disease Surveillance
- HIV Research and Treatment
- COVID-19 Digital Contact Tracing
- Health Systems, Economic Evaluations, Quality of Life
- Poisoning and overdose treatments
- Agriculture and Farm Safety
Centre de Recerca en Sanitat Animal
2011-2022
Universitat Autònoma de Barcelona
2006-2020
University of Minnesota
2015-2020
Banc de Sang i Teixits
2006-2008
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2008
Hospital Universitari Germans Trias i Pujol
2003-2006
CD14, a GPI-linked membrane protein, is component of the lipopolysaccharide (LPS) receptor complex, one pattern-recognizing receptors (PRR) expressed by myeloid lineage cells. Here we report that functionally linked toll-like molecules, TLR2 and TLR4, associated molecule MD-2 are in endocrine cells human pancreatic islets. CD14 expression islets was determined immunofluorescence staining tissue sections primary cultures, confirmed flow cytometry dispersed normal SV40-transformed islet...
ABSTRACT Identifying patterns and drivers of infectious disease dynamics across multiple scales is a fundamental challenge for modern science. There growing awareness that it necessary to incorporate multi‐host and/or multi‐parasite interactions understand predict current future threats better, new tools are needed help address this task. Eco‐phylogenetics (phylogenetic community ecology) provides one avenue exploring systems, yet the incorporation eco‐phylogenetic concepts methods into...
Flaviviruses of the Japanese encephalitis virus (JEV) antigenic complex, including West Nile (WNV), are recognized as emerging and reemerging pathogens. Circulation flaviviruses has been recently detected in different mosquito vertebrate species several European countries. A serosurvey study was carried out to evaluate circulation WNV other JEV complex wild bird Spain between 2006 2009. Seropositiviy against using a competitive enzyme-linked immunosorbent assay found common coot, Montagu's...
Summary To enhance early detection of W est N ile virus ( WNV ) transmission, an integrated ecological surveillance system was implemented in C atalonia (north‐eastern S pain) from 2007 to 2011. This incorporated passive and active equine surveillance, periodical testing chicken sentinels wetland areas, serosurveillance wild birds adult mosquitoes. Samples 298 equines, 100 sentinel chickens, 1086 39 599 mosquitoes were analysed. During these 5 years, no acute infection detected humans or...
Influenza is a costly disease for pig producers and understanding its epidemiology critical to control it. In this study, we aimed estimate the herd-level prevalence seasonality of influenza in breed-to-wean farms, evaluate correlation between meteorological conditions, characterize genetic diversity over time. A cohort 34 farms with monthly status obtained 5 year period piglets prior wean were selected. farm was considered positive given month if at least one oral fluid tested by RT-PCR....
Summary The destruction of β cells by the islet infiltrating lymphocytes causes type 1 diabetes. Transgenic mice models expressing interferon (IFN)-β in cells, non-obese diabetic (NOD) strain and a diabetes-free, major histocompatibility complex-matched, homologous strain, resistant (NOR) mice, developed accelerated diabetes after 3 weeks age. Our aim was to determine if natural killer (NK) could affect acceleration disease. We determined amount NK pancreas, spleen lymph nodes from NOD rat...
Between the years 2001 and 2005, a total of 72,895 female mosquitoes were trapped during their season abundance, analyzed. They sorted into 4,723 pools belonging to 20 Culicidae species from Anopheles, Aedes, Ochlerotatus, Culex, Culiseta, Coquillettidia, Uranotaenia genera. The aim was detect arboviral RNA directly mosquito homogenates for genera Alphavirus, Flavivirus, Phlebovirus. study formed part general arbovirus transmission research in four most important wetlands Spain; provinces...
Selection of an ideal sample is a vital element in early detection influenza infection. Rapid identification infectious individuals or animals crucial not only for avian virus (AIV) surveillance programmes, but also treatment and containment strategies. This study used combination quantitative real-time RT-PCR with internal positive control cell-titration system to examine the presence different samples during active experimental AIV infection its persistence infected carcasses....
Dolphin morbillivirus (DMV) has caused 2 epizootics with high mortality rates on the Spanish Mediterranean coast, in 1990 and 2006-07, mainly affecting striped dolphins Stenella coeruleoalba. Following first epizootic unusual DMV infections only central nervous system of were found, histological features similar to subacute sclerosing panencephalitis old dog encephalitis, chronic latent localised by defective forms measles virus canine distemper virus, respectively. Between 2008 2010,...
The importation of infected hosts and the arrival windborne Culicoides (Diptera: Ceratopogonidae) were considered unlikely mechanisms for bluetongue virus (BTV) incursion into a BTV-free area during recent BTV serotype 8 (BTV-8) epidemic in northern Europe. Therefore, alternative need to be considered. Air, sea land transport networks continue expand, an important consequence this is vector-borne pathogen importation. One aspect (BT) epidemiology not yet addressed potential movement via...
West Nile fever (WNF) is a viral zoonotic infection caused by mosquito-borne flavivirus of the Flaviviridae family. According to comparative study, passive surveillance horses equine veterinarians appeared be most cost-effective system in European context WNF. Clinical data issued from epidemiosurveillance network September 2010 December 2011 on Spain were statistically compared and used develop predictive diagnostic decision tree, both with aim improve early clinical detection WNF horses....
In Spain, the eradication of tuberculosis (TB) in cattle has had some setbacks and therefore we need to re-evaluate current surveillance strategies. The Spanish TB system consists three components: a) routine skin testing, b) slaughterhouse surveillance, c) pre-movement controls. Our objectives were assess effectiveness whole evaluate relative contribution each those components, both at national province level. was estimated based on sensitivity detection per year time until detection....
Wildlife rehabilitation centers routinely gather health-related data from diverse species. Their capability to signal the occurrence of emerging pathogens and improve traditional surveillance remains largely unexplored. This paper assessed utility for syndromic raptors admitted The Raptor Center (TRC) circulation West Nile Virus (WNV) in Minnesota between 1990 2014. An exhaustive descriptive analysis using grouping time series structures models interrupted times was conducted indicator...
Abstract Middle East respiratory syndrome coronavirus (MERS-CoV) remains a notable disease and poses significant threat to global public health. The Arabian Peninsula is considered major epicentre for the virus has crossed regional continental boundaries since 2012. In this study, we focused on exploring temporal dynamics of MERS-CoV in human populations between 2012 2017, using publicly available data case counts combining two analytical methods. Disease progression was assessed by...
Countries typically collect disease data in a way that is best suited for their specific needs.Therefore, differences exist the sampling schemes and diagnostic methods, which produce noncomparable and, subsequently, non-comparable estimates of prevalence disease.The objective HOTLINE project was to make information comparable interpretable across different testing settings.To serve this series Bayesian tools were developed applied.Reporting guidelines aimed at promoting more consistent...