Mathilde Del

ORCID: 0000-0003-2199-6188
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About
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Research Areas
  • Ovarian cancer diagnosis and treatment
  • Intraperitoneal and Appendiceal Malignancies
  • Endometrial and Cervical Cancer Treatments
  • Cancer Immunotherapy and Biomarkers
  • Appendicitis Diagnosis and Management
  • Colorectal Cancer Surgical Treatments
  • Endometriosis Research and Treatment
  • Venous Thromboembolism Diagnosis and Management
  • Respiratory Support and Mechanisms
  • Uterine Myomas and Treatments
  • Cytomegalovirus and herpesvirus research
  • Mechanical Circulatory Support Devices
  • Hernia repair and management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Renal cell carcinoma treatment
  • Aortic aneurysm repair treatments
  • Bladder and Urothelial Cancer Treatments
  • MRI in cancer diagnosis
  • Ureteral procedures and complications
  • Esophageal Cancer Research and Treatment
  • CNS Lymphoma Diagnosis and Treatment
  • Cutaneous Melanoma Detection and Management
  • Peripheral Artery Disease Management
  • Metastasis and carcinoma case studies
  • Lung Cancer Diagnosis and Treatment

Institut Claudius Regaud
2019-2025

University of Iowa Hospitals and Clinics
2024

Institut universitaire du cancer de Toulouse Oncopole
2022-2024

Society of Surgical Oncology
2019

10.1016/j.ijgc.2024.100624 article EN International Journal of Gynecological Cancer 2025-02-01

10.1016/j.ijgc.2024.101612 article EN International Journal of Gynecological Cancer 2025-02-01

10.1016/j.ijgc.2024.100179 article EN International Journal of Gynecological Cancer 2025-02-01

Acute limb ischemia following pelvic exenteration with laterally extended endopelvic resection is a rare yet severe complication. Prompt diagnosis essential for optimal treatment and recovery. This condition should be suspected if the patient presents rest pain, paresthesia, motor deficit or sensory loss. We report case of patient, diagnosed an acute right at day one sidewall recurrent cervical cancer after radiotherapy. Through collaboration multidisciplinary team, was successfully treated...

10.1016/j.gore.2025.101750 article EN cc-by Gynecologic Oncology Reports 2025-04-01

Primary lymphoma of the uterine cervix is a very infrequent disease, usually affecting perimenopausal women. Symptoms are similar to other gynecological malignancies, but treatment and prognosis completely differ, as most these patients have better survival. This condition has be suspected in women with recent normal Pap smear test, rapidly growing tumor initially non-contributory biopsies. We report case primary diffuse large-B-cell mimicking locally advanced cervical cancer right ureter...

10.1016/j.gore.2020.100639 article EN cc-by-nc-nd Gynecologic Oncology Reports 2020-09-11

Abstract Epithelial ovarian cancer is the most lethal gynecologic malignancy, with 5-year survival rates of 46%. High grade serous carcinoma (HGSC) frequent subtype epithelial cancer. Approximately 50% cases are homologous recombination deficient (HRD). Whereas maintenance treatment by PARP inhibitors has significantly improved prognosis patients HRD tumors, clinical outcome in this malignancy still poor. Despite immunogenic nature HGSC, which T-cell infiltration correlates to following...

10.1158/1538-7445.ovarian23-a076 article EN Cancer Research 2024-03-04

Data suggest an association between positron emission tomography/CT (PET/CT) metabolic metrics and tumor microenvironment in several malignancies, a potential role of PET/CT to monitor response immunotherapy. To evaluate the correlation loco-regional extension tumor-infiltrating lymphocyte infiltration locally advanced cervical cancer prior concurrent chemo-radiotherapy. The secondary objective was assess lymphocytes metrics. Patients with negative para-aortic extensions on were included....

10.1136/ijgc-2023-004677 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2024-03-12

<h3>Introduction/Background</h3> Vulvovaginal melanoma is a rare form of cancer, accounting for 1–2% melanomas in women. Prognosis poor, with high frequency metastatic forms at diagnosis and median survival rate 9 to 53 months. Immunotherapy has shown promising results cutaneous melanoma, but response rates vulvovaginal are much lower, indicating different immune microenvironment. Aim this study was assess the relation between microenvironment, survival, clinico-pathological characteristics...

10.1136/ijgc-2024-esgo.1056 article EN 2024-03-01

<h3>Introduction/Background</h3> Homologous recombination deficiency (HRD) exhibit distinct immune characteristics compared to HR Proficient (HRP) ovarian cancers. Tumor infiltrating lymphocytes (TILs) are enriched in HRD tumors, both through innate and adaptive mechanisms. However, there mechanisms for evading recognition the group, is a subset of HRP tumors with enhanced CD8 T cell response better survival. It likely that infiltration alone may not be sufficient characterize tumor...

10.1136/ijgc-2024-esgo.991 article EN 2024-03-01

<h3>Introduction/Background</h3> To perform surgical staging of early stage ovarian cancer (EOC), conventionnal laparoscopy (LS) and robot-assisted (RLS) appear to be reliable procedures compared open surgery. But oncologicals results with long-term follow up are limited in the literature. The objective this study is evaluate survival for patients managed by minimally invasive surgery (MIS). <h3>Methodology</h3> We conducted a multicentric retrospective 6 institutions. All refered epithelial...

10.1136/ijgc-2024-esgo.560 article EN 2024-03-01

Introduction: Bystander cardiopulmonary resuscitation (CPR) and automated external defibrillator (AED) use are interventions that can increase survival rates of out-of-hospital cardiac arrests (OHCA). However, willingness comfort levels such amongst laypersons vary greatly, especially in racial ethnic minoritized groups including African Americans Hispanics. Research Question: To assess the level perceived barriers participants before after community-based CPR AED education. Methods: We...

10.1161/circ.150.suppl_1.su1101 article EN Circulation 2024-11-12

Gastric perforation after cytoreductive surgery (CRS) is an infrequent complication. There lack of evidence regarding the risk factors for this postoperative The aim study was to assess prevalence gastric in patients undergoing CRS peritoneal carcinomatosis (PC) and evaluate predisposing complication.We designed a unicentric retrospective identify all who underwent open upfront or interval primary diagnosis PC different origins between March 2007 December 2018 at French Comprehensive Cancer...

10.1371/journal.pone.0248205 article EN cc-by PLoS ONE 2021-03-04

•Acute aortic abdominal dissection is a rare complication of retroperitoneal laparoscopic paraaortic lymph node dissection.•Aortic may be part differential diagnoses in patients with groin and pain after staging.•Uncomplicated type B should managed during the subacute phase.•Early contrast-enhanced computed tomography performed case lymphadenectomy.•Retroperitoneal at referral cancer centers.

10.1016/j.gore.2019.05.001 article EN cc-by-nc-nd Gynecologic Oncology Reports 2019-05-09

<h3>Introduction/Background</h3> The aim of our study was to assess concordance the staging laparoscopy and cytoreductive surgery peritoneal cancer index (PCI) when applying a two-step surgical protocol. We also aimed evaluate accuracy diagnostic triage patients for complete cytoreduction, define optimal time between surgery. <h3>Methodology</h3> designed retrospective review prospectively collected data from with advanced ovarian who underwent followed by few weeks later (two-step...

10.1136/ijgc-2019-esgo.1281 article EN 2019-11-01

<h3>Introduction/Background</h3> Cytoreductive surgery (CRS) is the mainstay of some peritoneal malignancies. To obtain complete cytoreduction, extensive with multiple visceral resections may be required. Gastric perforation an infrequent complication and it has been associated to hyperthermic intraperitoneal chemotherapy (HIPEC), mainly explained by a multifactorial etiology. <h3>Methodology</h3> We designed retrospective unicentric study identifying all patients who presented gastric after...

10.1136/ijgc-2019-esgo.789 article EN 2019-11-01
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