- Essential Oils and Antimicrobial Activity
- Toxin Mechanisms and Immunotoxins
- Arsenic contamination and mitigation
- Transgenic Plants and Applications
- Immune Response and Inflammation
- Stroke Rehabilitation and Recovery
- Heavy Metal Exposure and Toxicity
- Therapeutic Uses of Natural Elements
- Natural product bioactivities and synthesis
- Curcumin's Biomedical Applications
- Galectins and Cancer Biology
- Trace Elements in Health
- Andrographolide Research and Applications
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Inflammasome and immune disorders
- Computational Drug Discovery Methods
- Magnesium in Health and Disease
- vaccines and immunoinformatics approaches
- Wound Healing and Treatments
- Psychosomatic Disorders and Their Treatments
- Traditional Chinese Medicine Analysis
- Phytochemistry and Biological Activities
- Protein purification and stability
- Sirtuins and Resveratrol in Medicine
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Universidad Autónoma de Coahuila
2019-2024
Universidad Autónoma de La Laguna
2019-2023
Universidad Nacional Autónoma de México
2022
Universidad Juárez del Estado de Durango
2020
Abstract Chronic endemic regional hydroarsenicism (CERHA) is a global issue that affects over 200 million people exposed to arsenic (As) in drinking water. This includes 1.75 individuals residing La Comarca Lagunera, region north-central Mexico. Arsenic levels this typically exceeds the WHO guideline of 10 µg L −1 . Biochemical alterations related human As metabolism may increase risk overweight and obesity (O&O), type 2 diabetes (T2D), hypertension (AHT). In our study, we investigated...
ABSTRACT Chronic kidney disease (CKD) is characterized by progressive loss of function and irreversible structural changes. Both donation amikacin exhibit nephrotoxic effects; however, polyphenols like resveratrol are known for their nephroprotective properties due to antioxidant capabilities. This study investigates the protective effects in a renal injury model involving unilateral nephrectomy Wistar rats. Male rats ( n = 25) were divided into following five groups: (1) vehicle control,...
Background: The world's population is still growing, having an impact on the environment and economic growth of developing countries; so that, there a particular interest in development new fertility control methods, focused male contraception. Objective: objective this study was to evaluate effect methanolic extracts leaf fruit Azadirachta indica sperm quality testicular histology Long Evans rats. Methods: Antifertility effects A. 24 rats were investigated. animals randomly divided into two...
Background: Type 2 diabetes (T2DM) has been associated with deficiencies in serum magnesium level, decreasing insulin sensitivity and glucose metabolism. Glycosylated hemoglobin (Hb1Ac) is a biomarker of values within the half-life erythrocyte, that is, 3 months. Low circulating intracellular levels can modify metabolism sensitivity. Renal solute management parameter little used to estimate excreted concentrations elements such as magnesium. Objective: The purpose this study was assess...
Immunization or vaccination is the process of inducing artificial immunity against an antigen taking advantage mechanisms immunological memory. Current vaccines include substances known as adjuvants, which tend to improve immunogenicity antigen, reduce quantity employed, and boost immune response in weak responders. Unfortunately, only a few vaccine adjuvants are approved for human use.Thus, objective this study was investigate effect Tannic acid on humoral cell-mediated bovine serum albumin...
An antigen is a small foreign substance, such as microorganism structural protein, that may trigger an immune response once inside the body. Antigens are preferentially used rather than completely attenuated microorganisms to develop safe vaccines. Unfortunately, not all antigens able induce response. Thus, new adjuvants enhance antigen's ability stimulate immunity must be developed.Therefore, this work aimed evaluate molecular-structure adjuvant activity of tannic acid (TA) coupled protein...
Leptin levels and oxidative stress are implicated in obesity risk. Reports of association leptin gene (LEP) receptor (LEPR) polymorphisms with elevation contradictory a diverse population. Only few studies report the linkage biochemical markers genetic factors.The aim this study was to examine whether plasma lipid peroxidation, antioxidant capability, associate selected LEP -2548 A/G LEPR Q223R mestizo indigenous Mexican population.We identified characterized 50 overweight or obese subjects...
Una herida se define como corte o ruptura en la continuidad de cualquier tejido. El proceso curación heridas puede verse comprometido por infección, suministro inadecuado oxígeno, desnutrición y oxidativo, búsqueda alternativas que coadyuben los procesos cicatrización, evaluó actividad cicatrizante antioxidante del extracto etanólico propóleo (EEP). fue procesado obtuvo el EEP a diversas concentraciones µg/mL, cuantificó contenido polifenoles totales, capacidad diferentes métodos (ABTS, DPPH...
Mexico has the largest number of genus salvia plant species, whose main chemical compounds this are diterpenes, these have shown important biological activities such as: antimicrobial, anti-inflammatory and immunomodulatory.This study aimed to evaluate immunomodulatory activity three diterpenes: 1) icetexone, 2) anastomosine 3) 7,20-dihydroanastomosine, isolated from Salvia ballotiflora, over innate immunity cytokine production in a human alveolar epithelial cell line infected with...
Abstract Chronic endemic regional hydroarsenicism (CERHA) occurs worldwide, with millions of people exposed to arsenic (As) in drinking water. CERHA is present north-central Mexico, where As typically exceeds the WHO guideline (10 µg L − 1 ) and Mexican limits (25 ). Biochemical alterations related human metabolism may increase risk obesity, type 2 diabetes (T2D), hypertension (AHT). We conducted a case-control study address role water as factor for those metabolic diseases populations low...
Plants traditionally used for their antiviral activity could be an alternative against SARS-CoV-2. In this study, the efficacy of 10 bioactive plant compounds commonly in Mexico COVID-19 was evaluated by molecular docking with two online servers: Docking Server and DockThor. Remdesivir as a control. The results showed that Cypellocarpin B, C, Luteolin 7-glucoside Syringetin glucopyranoside highest affinity towards viral proteins Mpro RdRp respect to Remdesivir. Comparison servers differences...
Summary Streptococcus mutans has been associated with the development of dental caries. Semidesert bush Jatropha dioica Sessé, found in northern Mexico and widely used as traditional medicine, is known to inhibit pathogenic bacteria. The Folin–Ciocalteu method free radical capture by DPPH technique were determine total polyphenols (TP) antioxidant activity (AA) respectively. toxicity antimicrobial extract highest TP AA determined. value (46.06 mg GAE g −1 ) was determined dried root extract....
Background: The COVID-19 pandemic had infected more than 3.5M people around the world and 250K died in 187 countries by May 2020. causal agent of this disease is a coronavirus whose onset symptoms to death range from 6 41 days with median 14 days. This period dependent on several factors such as presence comorbidities, age efficiency innate or adaptive immune responses. Methods: effector mechanisms both types responses depend pathogen involved. In case viral infection, response may approach...