- Plasma Applications and Diagnostics
- Plasma Diagnostics and Applications
- Aerosol Filtration and Electrostatic Precipitation
- Electrostatic Discharge in Electronics
- Advanced ceramic materials synthesis
- Electrohydrodynamics and Fluid Dynamics
- Pancreatic function and diabetes
- Glycosylation and Glycoproteins Research
- Endometriosis Research and Treatment
- Escherichia coli research studies
- Mitochondrial Function and Pathology
- ATP Synthase and ATPases Research
- S100 Proteins and Annexins
- Toxin Mechanisms and Immunotoxins
- Catalytic Processes in Materials Science
- High-Temperature Coating Behaviors
- Thyroid Disorders and Treatments
- Acute Myeloid Leukemia Research
- Microbial bioremediation and biosurfactants
- Pulsed Power Technology Applications
- Cytokine Signaling Pathways and Interactions
- Organ and Tissue Transplantation Research
- Magnesium Oxide Properties and Applications
- Electron Spin Resonance Studies
- Male Breast Health Studies
University of Zurich
1981-2022
Forschungszentrum Jülich
2020-2021
Ruhr University Bochum
2021
University Hospital Münster
2008-2011
Klinik für Schlafmedizin
2009-2011
University of Münster
2008-2009
Soreq Nuclear Research Center
2004-2006
Israel Atomic Energy Commission
2004-2006
Institute of Environmental Engineering
2004
Philipps University of Marburg
1993-2001
Adult stem cells are thought to be responsible for the high regenerative capacity of human endometrium, and have been implicated in pathology endometriosis endometrial carcinoma. The RNA-binding protein Musashi-1 is associated with maintenance asymmetric cell division neural epithelial progenitor cells. We investigated expression localization endometrial, endometriotic carcinoma tissue specimens 46 patients. qPCR revealed significantly increased mRNA endometrium compared myometrium....
Abstract Rare earth silicate environmental barrier coatings (EBCs) are state of the art for protecting SiC ceramic matrix composites (CMCs) against corrosive media. The interaction four pure rare EBC materials Yb 2 SiO 5 , Si O 7 Y and three ytterbium mixtures with molten calcium‐magnesium‐aluminosilicate (CMAS) were studied at high temperature (1400°C). samples characterized by SEM XRD in order to evaluate recession different after a reaction time 8 hours. Additionally, coefficient thermal...
Solute quenching of the tryptophan fluorescence cholera toxin and its A B protomers has been investigated in prsence absence monosialoganglioside, galactosyl-N-acetylgalactosaminyl-[N-acetylneuraminyl]galactosylglucosylceramide (GM~), or oligosaccharide moiety GMI.Quenching constants obtained with a negatively charged quencher, iodide ion, conjunction positively N-methyl-4-picolinium indicate that residues protomer are exposed to solvent quencher.Fluorescence by ion protomer, but not is...
Abstract Bovine thyroid membranes possess both ADP ribosyltransferase and NAD glycohydrolase activities with the same Km values for pH optima. In intact membranes, is limited in its extent by amount of available membrane acceptor which can be ADP-ribosylated; solubilized lithium diiodosalicylate, an artificial acceptor, L-arginine methyl ester, substituted to eliminate this limitation. The product a mono-ADP-ribosylated whether or provides enzyme activity exogenous utilized. preparation also...
A technical overview of a European project on pulsed corona (PC) treatment polluted streams is presented. Versatile high-power systems that are capable cleaning both aqueous and gaseous in heterogeneous media, either above water reactor or an aerosol reactor, have been developed. Both reactors high-phenol removal yields from increase the biochemical oxygen demand/chemical demand ratio for several nonbiodegradable wastewaters to such degree further biodegradation becomes possible. The PC...
The tryptophan residues on cholera toxin and its A B protomers have been modified by reaction with 2-nitrophenylsulfenyl chloride 2,4-dinitrophenylsulfenyl chloride. Modification of the results in complete loss toxicity measured a skin permeability assay. protomer binding activity toward membrane receptors, ganglioside galactosyl-N-acetylgalactosaminyl-[N-acetylneuraminyl]-galactosylceramide (GM1), oligosaccharide moiety GM1. ADP-ribosylation exhibited their native counterparts. no apparent...
The system comprises an all solid-state compact nanosecond pulser and a plasma reactor. makes use of magnetic compression techniques. Owing to fast switching at the feed HV transformer provided by ABB GCT switch, one stage suffices for forming 45-kV, 100-ns pulses across 120-/spl Omega/ resistive load PRF up 1 kHz; risetime is 15 ns. Plasma reactor capable handling both gases liquids adding small amounts atomized water gas discharge, in case gas, or atomizing polluted liquid itself. In...
Thyrotropin increases the ADP-ribosylation activity of bovine thyroid membranes. Rapid membrane components is followed by increasing in supernatant reaction mixture. One major proteins ADP-ribosylated thyrotropin-stimulated has an approximate molecular weight 40,000; this same protein also a product A promoter cholera toxin and appears to be related G regulatory subunit adenylate cyclase complex. The products appearing solution comigrate with thyrotropin preparations 125I-labeled alpha...
The pulsed corona offers real promise for degradation of pollutants in gas and water streams. This paper presents a study NOx removal from diesel exhaust. Special emphasis is laid on the investigation dependence NO rate efficiency pulse repetition (PRR). A nanosecond solid state power supply (45 kV, 60 ns, up to 1 kHz) was used driving reactor. Mitsubishi 10 kW 3-cylinder diesel-generator engine with total volume 1300 cm3 as source exhaust gas. At an 35% 53 g kW−1h−1 PRR = 500 Hz initial...
The coupling factor AF 1 isolated from cells of the thermophilic blue‐green alga Mastigocladus laminosus grown at 40°C, 50°C and 60°C is investigated compared with chloroplast CF . It demonstrated that structure affected by growth temperature. shows a split α‐band in dodecylsulfate/polyacrylamide gel electrophoresis which not observed 40°C or 50°C. Only aggregates allophycocyanin. stable up to 85°C for 60 min whereas denture between 65°C 70°C. much less stable. In contrast structure, kinetic...
A combined mitochondrial and light fraction a microsomal were isolated from bovine thyroid gland fractionated further in B-XIV zonal rotor. density gradient ranging 20 to 50% (w/w) sucrose was used. The rotor operated for 3 h at 45 000 rev./min. All manipulations performed 4 degrees C pH 7.4. 2. Membranous material recovered two zones: zone I, containing derived both smooth endoplasmic reticulum plasma membranes probably also other membranes; II, rough reticulum. 3. Increasing the of medium...
Abstract Dense environmental barrier coatings (EBCs) are an essential prerequisite to exploit the advantages offered by SiC‐based fiber reinforced ceramic matrix composites (CMCs) increase efficiency in gas turbines. Today's state‐of‐the art materials for application as EBCs rare‐earth (RE) silicates which, however, form amorphous phases upon rapid quenching from melt. This makes their processing thermal spray a challenge. Recently, high velocity oxygen fuel (HVOF) spraying was proposed...
Enrichment cultures in a percolation apparatus with two different soil types supplemented bitumen, were used to follow growth on this complex substrate. Microscopic techniques allowed visualisation of bacteria solid surfaces bitumen and particles; quantification was only possible the fluid. In latter, changes pH amount organic material provided evidence for metabolic activities degradation substrate bitumen.
A concept and implementations of an innovative HV capacitor charger system based on resonant modular converter are described. This may function also as a DC power supply. The will be part pulsed supply in corona discharge for pollution control applications. comprises N identical modules fed parallel connected series at their outputs. They clocked by generator shifted pulses (for operation multi-phase mode), thus the ripple both input output is decreased dramatically. switching frequency...
This paper reports the ongoing effort on development of efficient, compact pulsed corona sources for pollution control applications. The system comprises an all-solid 4 kW average-power nanosecond pulser and a plasma reactor. is based single-stage magnetic compressor generating <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">~</sub> 50 kV, 1-5 J 50-100 ns pulses across multi-wire reactor having impedance approximately 100 Omega, at pulse...
The system comprises an all-solid state compact nanosecond pulser and a plasma reactor. makes use of magnetic compression techniques. Owing to fast switching at the feed HV transformer provided by ABB A-Z switch, one stage suffices for forming 45 kV, 100 ns pulses across 120 /spl Omega/ load; risetime is 20 ns. Plasma reactor capable handling both gases liquids adding small amounts atomized water gas discharge, in case gas, or atomizing polluted liquid itself. In cases, treatment conducted...
This paper presents a semi-empirical model for wire-wire corona reactor driven by capacitive storage solid-state pulse generator. The electrode system is configured as checker mesh of potential and grounded threaded electrodes, the generator based on modern magnetic compression topology. presentation considers effect geometrical parameters (the total length high-voltage surrounded its counterparts gap between electrodes) operation atmospheric pressure streamer plasma system. analyzes...
Abstract Direct metal laser deposition (DMLD) is commonly used for improving the surface quality of parts and additive manufacturing components. It can achieve faster throughput, better‐quality cladding, very low dilution levels, reduced heat input, minimal distortion, extremely porosity, improved uniformity. Taken together, these properties substantially reduce need time‐consuming costly post‐processing. DMLD also offers a wide range design options. Software‐assisted approaches make it...
In the high temperature combustion atmosphere inside of aircraft turbines, currently used ceramic matrix composites require a protective environmental barrier coating (EBC) to mitigate corrosion turbine parts. Besides thermomechanical and thermochemical properties like matching thermal expansion coefficient (CTE) resistance against corrosive media, mechanical adhesion strength are also necessary for long lifetime EBC. present work, between an air plasma sprayed silicon bond coat vacuum...
This paper reports the ongoing effort on development of efficient, compact pulsed corona sources for pollution control applications 1. The system comprises an all-solid state 2-kW average power (it can be doubled without change size), (<130 kg) nanosecond pulser and a plasma reactor. makes use magnetic compression techniques. One stage suffices forming 60 kV, 100 ns, 3 J pulses across reactor having impedance approximately Omega, at PRF up to 500 Hz; risetime is 15 ns. implemented as checker...