A5101701980- Atrial Fibrillation Management and Outcomes
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Neuropeptides and Animal Physiology
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular and Diving-Related Complications
- Pain Mechanisms and Treatments
- PARP inhibition in cancer therapy
- Mitochondrial Function and Pathology
- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Vitamin K Research Studies
- Astrophysics and Star Formation Studies
- Stellar, planetary, and galactic studies
- Liver physiology and pathology
- Rheumatoid Arthritis Research and Therapies
- Gamma-ray bursts and supernovae
- Lung Cancer Diagnosis and Treatment
- Electrolyte and hormonal disorders
- Medical Image Segmentation Techniques
- Immunotherapy and Immune Responses
- Cancer, Hypoxia, and Metabolism
First Affiliated Hospital of Kunming Medical University
2014-2025
Kunming Medical University
2014-2025
Sana Klinikum Lichtenberg
2019-2022
Laboratory of Molecular Genetics
2014
University of Rochester
2014
Nanjing University
2014
Peking University
2012
California Pacific Medical Center
2010
First Bethune Hospital of Jilin University
2010
Tsinghua University
2002-2005
The histological manifestation of growth-regulating and differentiation-inducing signals in cancer cells is considered as a key component for clinical outcome prediction commonly defined tumor differentiation grade. However, the molecular functional framework underlying this parameter remains poorly understood. Our correlative data display significant association (P>0.001) between mitochondrial uncoupling protein 2 (UCP2) grade primary breast (n=234). Through mechanistic analyses, we show...
The heart, responsible for circulating blood throughout our body, contains four chambers. Existing analysis methods primarily focus on one single ventricle. Transthoracic echocardiography provides real-time estimations of cardiac function and enables comprehensive observations the entire especially through apical 4-chamber view. However, no current clinical indices evaluate considering all chambers simultaneously. Manual estimation is laborious, inefficient, complicated by anatomical...
Abstract Background Inflammation is a major cause of temporomandibular disorder‐related pain. The N v 1.7 sodium channel has critical function in pain perceptions. However, whether and how the trigeminal ganglion involved joint ( TMJ ) inflammatory remains to be examined. Methods inflammation was induced by complete F reund's adjuvant female rats. expression ganglionic other channels examined using real‐time polymerase chain reaction or W estern blotting. Immunohistofluorescence with...
Rheumatic heart disease (RHD) is an autoimmune triggered by acute rheumatic fever (ARF). Matrix metalloproteinases (MMPs) play important role in the modulation of immune responses. The purpose this study was to evaluate association MMP1, 3, and 12 promoter polymorphisms with RHD a Han population Southern China since 3 genes are localized on same chromosome have combined effect. DNA samples were obtained from 90 adult patients control subjects. Polymorphisms MMP1 (rs1799750), MMP3...
To report long-term safety and efficacy of combined percutaneous LAA PFO/ASD closure.A retrospective study 370 consecutive patients undergoing LAAC procedures using the Watchman (WM) device. Data were compared between 330 cases only with procedure (Group I) 25/5 (PFO/ASD) sequential closure II).Compared to Group I, II had more males (86.7% vs. 65.8%, p < 0.05) a higher rate stroke (33.3% 10.6%, 0.01), but there no statistical differences in remaining patient characteristics. During follow-up...
We searched the light curves of over 40 000 stars in Two Micron All Sky Survey (2MASS) calibration data base, spanning approximately 4 yr, for objects that have significant day-long dimming events. also multi-colour red-dimming events could be due to transient extinction. In colour-independent sigma-limited search, we found 46 previously unrecognized eclipsing binaries, 6 periodic variable likely intrinsic pulsators and 21 young stellar ρ Ophiuchus star formation region studied by Parks et...
Introduction Percutaneous coronary intervention (PCI) guided by angiography-derived fractional flow reserve (FFR) or intravascular ultrasound (IVUS) has shown improved clinical outcomes compared with angiography-only-guided PCI. In patients intermediate stenoses, FFR resulted in fewer interventions and was non-inferior to IVUS respect outcomes. However, whether this finding can be applied significant artery disease (CAD) remains unclear. Method analysis The comparison of FFR-guided...
Introduction: Patients with non-valvular atrial fibrillation (NVAF) and previous stroke are at significantly higher risk of recurrence. Data on the efficacy left appendage closure (LAAC) these patients is limited. The aim this study was to investigate differences LAAC long-term cardio- cerebrovascular outcomes in NVAF vs. without prior stroke. Methods: Three hundred seventy consecutive who underwent were enrolled divided into non-stroke groups based history Endpoints, such as...
Higher CHA2DS2-VASc score is associated with an increased risk of adverse cardio-cerebrovascular events in patients non-valvular atrial fibrillation (NVAF), regardless oral anticoagulation (OAC) status. However, whether this association still exists undergoing left appendage closure (LAAC) unknown. We evaluated the impact on LAAC efficacy and outcomes.A total 401 consecutive were included divided into 3 groups based (0-2, 3-4, ≥5). Baseline characteristics, periprocedural complications,...
In China, hypertension has become a dangerous factor to public health in recent years. To study its impact on status, exercise testing was developed examine the changes of physiological parameters. 107 patients and 68 healthy persons were volunteers for this testing. During testing, ECG, pulse wave, respiratory wave blood pressure recorded. According parameters measured, WHOQOL-BERF results completed by all subjects, evaluation based physical function, statistical analysis carried out using...
Li, W.1; Bakthavatsalam, R.2; Meng, Z.3; Perkins, J. D.4; Reyes, D.4 Author Information
Abstract Purpose: Left atrial appendage closure (LAAC) may present an alternative to anticoagulation in patients with non-valvular fibrillation (NVAF). However, evidence regarding benefit of LAAC prior major bleeding is limited. We evaluate whether a previous factor influences the safety and effectiveness LAAC. Methods: A total 377 consecutive scheduled for were categorized into group (n=137) non-bleeding (n=240). The implantation success prevalence severe peri-procedural complications,...