A5027385857- Bone Tissue Engineering Materials
- melanin and skin pigmentation
- Metallic Glasses and Amorphous Alloys
- biodegradable polymer synthesis and properties
- Advanced Photocatalysis Techniques
- Photoacoustic and Ultrasonic Imaging
- Nanoplatforms for cancer theranostics
- Skin Protection and Aging
- TiO2 Photocatalysis and Solar Cells
- Catalytic Processes in Materials Science
- Advanced Nanomaterials in Catalysis
- Gold and Silver Nanoparticles Synthesis and Applications
- Chemical Looping and Thermochemical Processes
- Glass properties and applications
- Luminescence Properties of Advanced Materials
- Silk-based biomaterials and applications
- Dental materials and restorations
- Polymer Nanocomposites and Properties
- Catalysts for Methane Reforming
- Combustion and Detonation Processes
- Dyeing and Modifying Textile Fibers
- Polymer Surface Interaction Studies
- Nanocomposite Films for Food Packaging
- Mesoporous Materials and Catalysis
- Hydrogels: synthesis, properties, applications
University of Naples Federico II
2016-2025
Yale University
2025
Centro Interuniversitario di Ricerca sui Peptidi Bioattivi
2016
Center for Advanced Biomaterials for Healthcare
2015
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli
2015
Engineering (Italy)
2012
California Pacific Medical Center
2010
Istituto Nazionale per la Fisica della Materia
2002
Sustainable active food packaging is essential to reduce the use of plastics, preserve quality and minimize environmental impact. Humic substances (HS) are rich in redox-active compounds, such as quinones, phenols, carboxyl, hydroxyl moieties, making them functional additives for biopolymeric matrices, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV). Herein, composites made by incorporating different amounts HS into PHBV were developed using electrospinning technology converted...
Different spectroscopic techniques have been applied to fluorine doped ZnO powders prepared through hydrothermal synthesis, discern the effective capability of F atoms improve conductivity. From XRD analysis, no lattice distortion was observed up doping at 5 at. % concentration. Photoluminescence measurements and electron paramagnetic resonance data show that tend occupy oxygen vacancies, inducing onset luminescence centers. The resulting effect consists into increment localized charge, as...
Solar radiation is becoming increasingly appreciated because of its influence on living matter and the feasibility application for a variety purposes. It an available everlasting natural source energy, rapidly gaining ground as supplement alternative to nonrenewable energy feedstock. Actually, increasing interest involved in development efficient materials core photocatalytic photothermal processes, allowing solar harvesting conversion many technological applications, including hydrogen...
Following a waste-to-wealth approach, humic acid (HA) was exploited as flame retardant additive. The effect of its addition alone and in combination with urea (UR) ammonium polyphosphate (APP) on the thermal, fire, mechanical performances bisphenol A diglycidyl ether (DGEBA)-based epoxy resin modified (3-aminopropyl)-triethoxysilane (AP) cured aliphatic isophoronediamine (IDA) has been investigated. Unlike previous studies, UL 94-V-0 classification achieved for containing HA at 6 wt % APP...
Exploring opportunities for biowaste valorization, herein, humic substances (HS) were combined with gelatin, a hydrophilic biocompatible and bioavailable polymer, to obtain 3D hydrogels. Hybrid gels (Gel HS) prepared at different HS contents, exploiting physical or chemical cross-linking, through 1-ethyl-(3-3-dimethylaminopropyl)carbodiimide (EDC) chemistry, between gelatin. Physicochemical features assessed rheological measurements, X-ray diffraction, attenuated total reflectance (ATR)...
Sustainable packaging materials can play a key role in minimizing the environmental footprint of packaged food by preserving its quality and avoiding persistence plastic waste. Waste to wealth approach cope with these major challenges providing for bioavailable active compounds from waste residues. To this regard, humic substances (HS), derived biowaste oxidative processes, exhibit intrinsic antioxidant antimicrobial features, which be significantly boosted molecular combination an inorganic...
Melanin is a multifunctional biological pigment that recently emerged as endowed with anti-inflammatory, antioxidant, and antimicrobial properties high potentialities in skin protection regenerative medicine. Here, biomimetic magnesium-doped nano-hydroxyapatite (MgHA) was synthesized decorated melanin molecules starting from two different monomeric precursors, i.e. 5,6-dihydroxyindole-2-carboxylic acid (DHICA) dopamine (DA), demonstrating to be able polymerize on the surface of MgHA...
It is largely documented that neurodegenerative diseases can be effectively treated only if early diagnosed. In this context, the structural changes of some biomolecules such as Tau, seem to play a key role in neurodegeneration mechanism becoming eligible targets for an diagnosis. Post-translational modifications are responsible drive Tau protein towards transition phase from native disorder conformation into preaggregation state, which then straight recruits final fibrillization process....
Exploring the chance to convert biowaste into a valuable resource, this study tests potential role of humic acids (HA), class multifunctional compounds obtained by oxidative decomposition biomass, as physical agents improve gelatin's mechanical and thermal properties. To purpose, gelatin-HA aqueous samples were prepared at increasing HA content. HA/gelatin concentrations changed in range 2.67-26.67 (wt/wt)%. Multiple techniques employed assess influence content on gel properties unveil...
Redox-active nano-biointerfaces are gaining weight in the field of regenerative medicine since they can act as enzymes regulating physiological processes and enabling cell homeostasis, well defense against pathogen aggression. In particular, cerium oxide nanoparticles (CeO2 NPs) stand intriguing enzyme-mimicking nanoplatforms, owing to reversible Ce+3/Ce+4 surface oxidation state. Moreover, functionalization leads higher catalytic activity selectivity, more tunable performances. Conjugation...
Here we demonstrate for the first time that an antibody-gold nanoparticles (AuNPs)-polymer conjugate thin-film biosensor can easily be fabricated to selectively capture Tau protein. Gold (AuNPs) are employed as sensing elements, thus capitalizing on their propensity undergo assembly or disassembly in response adsorption conjugation of various biomolecules surface, thereby forming robust interactions with target analyte. We show protein its different aggregation phases detected, by...
The histological manifestation of growth-regulating and differentiation-inducing signals in cancer cells is considered as a key component for clinical outcome prediction commonly defined tumor differentiation grade. However, the molecular functional framework underlying this parameter remains poorly understood. Our correlative data display significant association (P>0.001) between mitochondrial uncoupling protein 2 (UCP2) grade primary breast (n=234). Through mechanistic analyses, we show...
We disclose herein the first example of stable monodispersed hybrid nanoparticles (termed MelaSil-NPs) made up eumelanin biopolymer intimately integrated into a silica nanoscaffold matrix and endowed with high antioxidant cytoprotective effects associated specific subcellular localization. MelaSil-NPs have been fabricated by an optimized sol-gel methodology involving ammonia-induced oxidative polymerization covalent conjugate building block 5,6-dihydroxyindole-2-carboxylic acid (DHICA)...
Intrinsic biocide efficacy of eumelanins can be markedly enhanced through a templated formation in the presence TiO2-sol, leading to hybrid TiO2-melanin nanostructures. However, mechanisms and processes behind activity still remain poorly understood. This paper discloses fundamental mechanism action these systems providing mechanistic information on their peculiar interaction with Escherichia coli strains. To this purpose characterization is combined Electron Paramagnetic Resonance (EPR)...
Bioconjugation of a recently developed photoacoustic nanoprobe, based on silica-templated eumelanin-silver hybrid nanoparticles (MelaSil_Ag-NPs), with human serum albumin (HSA) is disclosed herein as an efficient and practical strategy to improve photostability perform SPARC mediated internalization in breast cancer cells. Modification NPs HSA induced slight viability decrease cells (HS578T) normal (MCF10a) when incubated HSA-NPs up 100 μg/mL concentration for 72h complete suppression...