Kaci DeJarnette

ORCID: 0000-0003-2218-996X
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About
Contact & Profiles
Research Areas
  • Antifungal resistance and susceptibility
  • Tracheal and airway disorders
  • Fungal Infections and Studies
  • Peptidase Inhibition and Analysis
  • Neuroscience of respiration and sleep
  • Health Literacy and Information Accessibility
  • Obstructive Sleep Apnea Research

University of Tennessee Health Science Center
2019-2022

Protein prenylation is a crucial post-translational modification largely mediated by two heterodimeric enzyme complexes, farnesyltransferase and geranylgeranyltransferase type-I (GGTase-I), each composed of shared α-subunit unique β-subunit. GGTase-I enzymes are validated drug targets that contribute to virulence in Cryptococcus neoformans the yeast-to-hyphal transition Candida albicans. Therefore, we sought investigate importance α-subunit, RamB, β-subunit, Cdc43, A. fumigatus complex...

10.1080/21505594.2019.1620063 article EN cc-by Virulence 2019-01-01
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