A5014867752- Cancer-related molecular mechanisms research
- Sperm and Testicular Function
- MicroRNA in disease regulation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- RNA modifications and cancer
- Circular RNAs in diseases
- Reproductive Biology and Fertility
- Sexual Differentiation and Disorders
- Animal Genetics and Reproduction
- Ovarian function and disorders
- RNA Research and Splicing
- Chromosomal and Genetic Variations
University of Belgrade
2015-2023
University of Belgrade – Faculty of Biology
2015
Results of recent studies confirmed that oxidative stress negatively affects sperm motility and causes DNA damage. Produced by nitric oxide synthase 3 (NOS3), is considered to be one the important mediators in testis tissue. The aim this study was assess possible association three genetic variants (rs2070744, rs1799983 intron variant 4a/4b) NOS3 gene infertility occurrence two groups infertile men (idiopathic azoospermia oligoasthenozoospermia) fertile controls. Genotypes for...
PRMT6, PEX10 and SOX5 genetic variants were identified as male infertility-associated loci in a genome-wide association study further validated various populations. Still, the results of previous case-control studies varied, which could be due to differences participants? ethnic backgrounds. The main purpose present was evaluate supposed these with idiopathic infertility North Macedonian population. Furthermore, we aimed conduct systematic quantitative data synthesis includes on same issue...
Results of numerous studies gave contradictory conclusions when analysing associations between copy number variants (CNVs) within the azoospermia factor (AZF) locus Y chromosome and idiopathic male infertility. The aim this study was to identify presence possible association CNVs in AZF region with infertility Serbian population. Using multiplex ligation-dependent probe amplification technique, we were able detect 24 105 (22.86%) infertile men 11 112 (9.82%) fertile controls. results...